Search Results - "Vondenhoff, Gaston H"

Aminoacyl-tRNA synthetase inhibitors as potential antibiotics by Vondenhoff, Gaston H.M., Van Aerschot, Arthur

“…Increasing resistance to antibiotics is a major problem worldwide and provides the stimulus for development of new bacterial inhibitors with preferably…”
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Synthetic Microcin C Analogs Targeting Different Aminoacyl-tRNA Synthetases by VAN DE VIJVER, Pieter, VONDENHOFF, Gaston H. M, KAZAKOV, Teymur S, SEMENOVA, Ekaterina, KUZNEDELOV, Konstantin, METLITSKAYA, Anastasia, VAN AERSCHOT, Arthur, SEVERINOV, Konstantin

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Characterization of Peptide Chain Length and Constituency Requirements for YejABEF-Mediated Uptake of Microcin C Analogues by VONDENHOFF, Gaston H. M, BLANCHAERT, Bart, GEBOERS, Sophie, KAZAKOV, Teymur, DATSENKO, Kirill A, WANNER, Barry L, ROZENSKI, Jef, SEVERINOV, Konstantin, AERSCHOT, Arthur Van

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N-alkylated aminoacyl sulfamoyladenosines as potential inhibitors of aminoacylation reactions and microcin C analogues containing D-amino acids by Vondenhoff, Gaston H, Pugach, Ksenia, Gadakh, Bharat, Carlier, Laurence, Rozenski, Jef, Froeyen, Mathy, Severinov, Konstantin, Van Aerschot, Arthur

“…Microcin C analogues were recently envisaged as important compounds for the development of novel antibiotics. Two issues that may pose problems to these…”
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Escherichia coli Peptidase A, B, or N Can Process Translation Inhibitor Microcin C by Kazakov, Teymur, Vondenhoff, Gaston H, Datsenko, Kirill A, Novikova, Maria, Metlitskaya, Anastasia, Wanner, Barry L, Severinov, Konstantin

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Maturation of the Translation Inhibitor Microcin C by Metlitskaya, Anastasia, Kazakov, Teymur, Vondenhoff, Gaston H, Novikova, Maria, Shashkov, Alexander, Zatsepin, Timofei, Semenova, Ekaterina, Zaitseva, Natalia, Ramensky, Vasily, Van Aerschot, Arthur, Severinov, Konstantin

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Extended targeting potential and improved synthesis of Microcin C analogs as antibacterials by Vondenhoff, Gaston H.M., Dubiley, Svetlana, Severinov, Konstantin, Lescrinier, Eveline, Rozenski, Jef, Van Aerschot, Arthur

“…Microcin C (McC) (1) is a potent antibacterial compound produced by some Escherichia coli strains. McC functions through a Trojan-Horse mechanism: it is…”
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Microcin C and Albomycin Analogues with Aryl-tetrazole Substituents as Nucleobase Isosters Are Selective Inhibitors of Bacterial Aminoacyl tRNA Synthetases but Lack Efficient Uptake by Vondenhoff, Gaston H., Gadakh, Bharat, Severinov, Konstantin, Van Aerschot, Arthur

“…In 1998, Cubist Pharmaceuticals patented a series of aminoacyl tRNA synthetase (aaRS) inhibitors based on aminoacyl sulfamoyladenosines (aaSAs), in which the…”
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RimL Transacetylase Provides Resistance to Translation Inhibitor Microcin C by Kazakov, Teymur, Kuznedelov, Konstantin, Semenova, Ekaterina, Mukhamedyarov, Damir, Datsenko, Kirill A, Metlitskaya, Anastasija, Vondenhoff, Gaston H, Tikhonov, Anton, Agarwal, Vinayak, Nair, Satish, Van Aerschot, Arthur, Severinov, Konstantin

“…Peptide-nucleotide antibiotic microcin C (McC) is produced by some Escherichia coli strains. Inside a sensitive cell, McC is processed, releasing a…”
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MccE Provides Resistance to Protein Synthesis Inhibitor Microcin C by Acetylating the Processed Form of the Antibiotic by Novikova, Maria, Kazakov, Teymur, Vondenhoff, Gaston H., Semenova, Ekaterina, Rozenski, Jef, Metlytskaya, Anastasija, Zukher, Inna, Tikhonov, Anton, Van Aerschot, Arthur, Severinov, Konstantin

“…The heptapeptide-nucleotide microcin C (McC) is a potent inhibitor of enteric bacteria growth. McC is excreted from producing cells by the MccC transporter…”
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Microcin C: Biosynthesis, Mode of Action, and Potential as a Lead in Antibiotics Development by Vondenhoff, Gaston H. M., Van Aerschot, Arthur

“…The natural compound Microcin C (McC) is a Trojan horse inhibitor of aspartyl tRNA synthetases endowed with strong antibacterial properties, in which a…”
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Microcin C and McC-like compounds are novel potential inhibitors of translation by Novikova, Maria, Metlitskaya, Anastasia, Kazakov, Teymur, Vondenhoff, Gaston H., Van Aerschot, Arthur, Severinov, Konstantin

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Extended targeting potential and improved synthesis of Microcin C analogs as antibacterials by VONDENHOFF, Gaston H. M, DUBILEY, Svetlana, SEVERINOV, Konstantin, LESCRINIER, Eveline, ROZENSKI, Jef, VAN AERSCHOT, Arthur

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Maturation of the Translation Inhibitor Microcin C by METLITSKAYA, Anastasia, KAZAKOV, Teymur, SEVERINOV, Konstantin, VONDENHOFF, Gaston H, NOVIKOVA, Maria, SHASHKOV, Alexander, ZATSEPIN, Timofei, SEMENOVA, Ekaterina, ZAITSEVA, Natalia, RAMENSKY, Vasily, VAN AERSCHOT, Arthur

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Escherichia coli Peptidase A, B, or N Can Process Translation Inhibitor Microcin C by KAZAKOV, Teymur, VONDENHOFF, Gaston H, DATSENKO, Kirill A, NOVIKOVA, Maria, METLITSKAYA, Anastasia, WANNER, Barry L, SEVERINOV, Konstantin

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