Search Results - "Von der Lieth, C W"
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GlycoMapsDB: a database of the accessible conformational space of glycosidic linkages
Published in Nucleic acids research (01-01-2007)“…Conformational energy maps of the glycosidic linkages are a valuable resource to gain information about preferred conformations and flexibility of…”
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SWEET - WWW-based rapid 3D construction of oligo- and polysaccharides
Published in Bioinformatics (01-09-1999)“…SWEET is a WWW-based tool which rapidly converts the commonly used carbohydrate sequence information directly into a preliminary but reliable 3D model which…”
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Identification of a Heparin-Binding Motif on Adeno-Associated Virus Type 2 Capsids
Published in Journal of Virology (01-10-2003)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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LOX-DB—a database on lipoxygenases
Published in Bioinformatics (12-12-2003)“…Lipoxygenases are a family of enzymes involved in a variety of human diseases like inflammation, asthma, artherosclerosis and cancer. The lipoxygenases…”
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Towards defining the role of glycans as hardware in information storage and transfer: basic principles, experimental approaches and recent progress
Published in Cells, tissues, organs (01-01-2001)“…The term 'code' in biological information transfer appears to be tightly and hitherto exclusively connected with the genetic code based on nucleotides and…”
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GlyProt: in silico glycosylation of proteins
Published in Nucleic acids research (01-07-2005)“…GlyProt (http://www.glycosciences.de/glyprot/) is a web-based tool that enables meaningful N-glycan conformations to be attached to all the spatially…”
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Medicinal chemistry based on the sugar code: fundamentals of lectinology and experimental strategies with lectins as targets
Published in Current medicinal chemistry (01-04-2000)“…Theoretical calculations reveal that oligosaccharides are second to no other class of biochemical oligomery in terms of coding capacity. As integral part of…”
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GlycoFragment and GlycoSearchMS: web tools to support the interpretation of mass spectra of complex carbohydrates
Published in Nucleic acids research (01-07-2004)“…In recent years, mass spectrometry has become the method of choice for high-sensitivity glycan identification. Currently, only a few tools assisting mass…”
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PubFinder: a tool for improving retrieval rate of relevant PubMed abstracts
Published in Nucleic acids research (01-07-2005)“…Since it is becoming increasingly laborious to manually extract useful information embedded in the ever-growing volumes of literature, automated intelligent…”
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10
Bioinformatics for glycomics: Status, methods, requirements and perspectives
Published in Briefings in bioinformatics (01-06-2004)“…The term 'glycomics' describes the scientific attempt to identify and study all the glycan molecules - the glycome - synthesised by an organism. The aim is to…”
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The structural basis for the mutagenicity of aristolochic acid
Published in Cancer letters (19-11-1990)“…Molecular orbital calculations with aristolochic acid I (AAI) and the model compounds 8-nitro-1-naphthoic acid (1,8NNA) and 3-nitro-2-naphthoic acid (2,3NNA)…”
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Solution conformations of GM3 gangliosides containing different sialic acid residues as revealed by NOE-based distance mapping, molecular mechanics, and molecular dynamics calculations
Published in Biochemistry (Easton) (04-08-1992)“…The conformation of the GM3 ganglioside, Neu5Ac alpha 2-3Gal beta 1-4Glc beta 1-1 Cer, and its analogs containing the Neu5Gc or Neu4Ac5Gc residues (Gc =…”
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Sharing of worldwide distributed carbohydrate-related digital resources: online connection of the Bacterial Carbohydrate Structure DataBase and GLYCOSCIENCES.de
Published in Nucleic acids research (01-01-2007)“…Functional glycomics, the scientific attempt to identify and assign functions to all glycan molecules synthesized by an organism, is an emerging field of…”
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Carbohydrate Structure Suite (CSS): analysis of carbohydrate 3D structures derived from the PDB
Published in Nucleic acids research (01-01-2005)“…Knowledge of the 3D structure of glycoproteins and protein–carbohydrate complexes is indispensable to fully understand the biological processes they are…”
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Translesional synthesis on DNA templates containing site-specifically placed deoxyadenosine and deoxyguanosine adducts formed by the plant carcinogen aristolochic acid
Published in Carcinogenesis (New York) (01-10-1994)“…Synthetic oligonucleotides (18-mers) containing either a single deoxyadenosine residue or a single deoxyguanosine residue were treated with aristolochic acid I…”
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16
Bispecific tandem diabody for tumor therapy with improved antigen binding and pharmacokinetics
Published in Journal of molecular biology (15-10-1999)“…To increase the valency, stability and therapeutic potential of bispecific antibodies, we designed a novel recombinant molecule that is bispecific and…”
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LINUCS: LInear Notation for Unique description of Carbohydrate Sequences
Published in Carbohydrate research (01-11-2001)“…The use of proteomics databases has become indispensable for daily work of molecular biologists, but this situation has not yet been achieved for carbohydrate…”
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SWEET-DB: an attempt to create annotated data collections for carbohydrates
Published in Nucleic acids research (01-01-2002)“…Complex carbohydrates are known as mediators of complex cellular events. Concerning their structural diversity, their potential of information content is…”
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Monosaccharide-linked inhibitors of O(6)-methylguanine-DNA methyltransferase (MGMT): synthesis, molecular modeling, and structure-activity relationships
Published in Journal of medicinal chemistry (22-11-2001)“…A series of potential inhibitors of the human DNA repair protein O(6)-methylguanine-DNA methyltransferase (MGMT) were synthesized, characterized in detail by…”
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GLYCO-FRAGMENT: A web tool to support the interpretation of mass spectra of complex carbohydrates
Published in Proteomics (Weinheim) (01-10-2003)“…Mass spectrometry is frequently used to analyze complex oligosaccharides and glycopeptides. The spectra of glycans can be complicated and difficult to…”
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