Controlling a vancomycin-resistant enterococci outbreak in a Brazilian teaching hospital

The purpose of this article was to describe a 2.5-year interventional program designed to control the dissemination after a large hospital outbreak of vancomycin-resistant enterococci (VRE) in a tertiary-care university hospital. A VRE working group was designated to work specifically on controlling...

Full description

Saved in:

Bibliographic Details
Published in:	European journal of clinical microbiology & infectious diseases Vol. 30; no. 3; pp. 369 - 374
Main Authors:	Moretti, M. L, de Oliveira Cardoso, L. G, Levy, C. E, Von Nowakosky, A, Bachur, L. F, Bratfich, O, Leichsenring, M. L, Fagnani, R, Peres Evangelista Dantas, S. M, Resende, M. R, Trabasso, P
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Berlin/Heidelberg : Springer-Verlag 01-03-2011 Springer-Verlag Springer Springer Nature B.V
Subjects:	Antibiotic resistance Biological and medical sciences Biomedical and Life Sciences Biomedicine Brazil - epidemiology Cross Infection - epidemiology Cross Infection - microbiology Cross Infection - prevention & control Disease control Disease Outbreaks - prevention & control Electrophoresis, Gel, Pulsed-Field Enterococcus - drug effects Gastroenterology Gram-Positive Bacterial Infections - epidemiology Gram-Positive Bacterial Infections - microbiology Gram-Positive Bacterial Infections - prevention & control Hospitalization Hospitals, Teaching Humans Infection Control Infectious diseases Internal Medicine Medical Microbiology Medical sciences Nosocomial infections Outbreaks Population Surveillance Teaching hospitals Vancomycin Resistance Working groups South America Brazil America Infection Control Measure Rectal Swab Contact Precaution Colonization Pressure Antimicrobial Stewardship Program Enterococcus Epidemic Infection Streptococcaceae Teaching hospital Microbiology Bacteria Micrococcales
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The purpose of this article was to describe a 2.5-year interventional program designed to control the dissemination after a large hospital outbreak of vancomycin-resistant enterococci (VRE) in a tertiary-care university hospital. A VRE working group was designated to work specifically on controlling VRE intrahospital dissemination after the detection of the first VRE infection at in our hospital in June 2007. The intervention consisted in the interruption of new admissions during a period of 15 days and closure of the index case unit, microbiological surveillance of rectal swabs for VRE, cohorting patients and staff, immediate application of contact precautions, and continuous education. From July 2007 to December 2009, 8,692 rectal swabs were cultured for VRE and 321 (3.7%) were positive. An expressive reduction of the detection of new positive rectal swabs cultures was seen during the year 2009 (1.5%) when compared to 2008 (4.2%) and 2007 (7.2%) (p < 0.005). The annual ratio of VRE per 1,000 admissions reduced from 20.3 in 2007 to 10.07 and 3.82 in 2008 and 2009, respectively (p < 0.001). The continuous microbiologic surveillance for VRE and strict and prompt contact precautions for VRE patients were the fundamental aids in the control of VRE.
Bibliography:	http://dx.doi.org/10.1007/s10096-010-1095-8 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1
ISSN:	0934-9723 1435-4373
DOI:	10.1007/s10096-010-1095-8