Search Results - "Von Holle, Tarra"

Influenza and Antibody-Dependent Cellular Cytotoxicity by Von Holle, Tarra A, Moody, M Anthony

“…Despite the availability of yearly vaccinations, influenza continues to cause seasonal, and pandemic rises in illness and death. An error prone replication…”
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Infant Antibody Repertoires during the First Two Years of Influenza Vaccination by Kuraoka, Masayuki, Curtis, Nicholas C, Watanabe, Akiko, Tanno, Hidetaka, Shin, Seungmin, Ye, Kevin, Macdonald, Elizabeth, Lavidor, Olivia, Kong, Susan, Von Holle, Tarra, Windsor, Ian, Ippolito, Gregory C, Georgiou, George, Walter, Emmanuel B, Kelsoe, Garnett, Harrison, Stephen C, Moody, M Anthony, Bajic, Goran, Lee, Jiwon

“…The first encounter with influenza virus biases later immune responses. This "immune imprinting," formerly from infection within a few years of birth, is in…”
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Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth by Huang, Jinghe, Kang, Byong H., Ishida, Elise, Zhou, Tongqing, Griesman, Trevor, Sheng, Zizhang, Wu, Fan, Doria-Rose, Nicole A., Zhang, Baoshan, McKee, Krisha, O’Dell, Sijy, Chuang, Gwo-Yu, Druz, Aliaksandr, Georgiev, Ivelin S., Schramm, Chaim A., Zheng, Anqi, Joyce, M. Gordon, Asokan, Mangaiarkarasi, Ransier, Amy, Darko, Sam, Migueles, Stephen A., Bailer, Robert T., Louder, Mark K., Alam, S. Munir, Parks, Robert, Kelsoe, Garnett, Von Holle, Tarra, Haynes, Barton F., Douek, Daniel C., Hirsch, Vanessa, Seaman, Michael S., Shapiro, Lawrence, Mascola, John R., Kwong, Peter D., Connors, Mark

“…Detailed studies of the broadly neutralizing antibodies (bNAbs) that underlie the best available examples of the humoral immune response to HIV are providing…”
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Differential immune imprinting by influenza virus vaccination and infection in nonhuman primates by McCarthy, Kevin R., Von Holle, Tarra A., Sutherland, Laura L., Oguin, Thomas H., Sempowski, Gregory D., Harrison, Stephen C., Moody, M. Anthony

“…Immune memory of a first infection with influenza virus establishes a lasting imprint. Recall of that memory dominates the response to later infections or…”
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HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces gp41 Antibody Immunodominance in Rhesus Macaques by Han, Qifeng, Williams, Wilton B, Saunders, Kevin O, Seaton, Kelly E, Wiehe, Kevin J, Vandergrift, Nathan, Von Holle, Tarra A, Trama, Ashley M, Parks, Robert J, Luo, Kan, Gurley, Thaddeus C, Kepler, Thomas B, Marshall, Dawn J, Montefiori, David C, Sutherland, Laura L, Alam, Munir S, Whitesides, John F, Bowman, Cindy M, Permar, Sallie R, Graham, Barney S, Mascola, John R, Seed, Patrick C, Van Rompay, Koen K A, Tomaras, Georgia D, Moody, M Anthony, Haynes, Barton F

“…Dominant antibody responses in vaccinees who received the HIV-1 multiclade (A, B, and C) envelope (Env) DNA/recombinant adenovirus virus type 5 (rAd5) vaccine…”
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In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies by Li, Dapeng, Edwards, Robert J., Manne, Kartik, Martinez, David R., Schäfer, Alexandra, Alam, S. Munir, Wiehe, Kevin, Lu, Xiaozhi, Parks, Robert, Sutherland, Laura L., Oguin, Thomas H., McDanal, Charlene, Perez, Lautaro G., Mansouri, Katayoun, Gobeil, Sophie M.C., Janowska, Katarzyna, Stalls, Victoria, Kopp, Megan, Cai, Fangping, Lee, Esther, Foulger, Andrew, Hernandez, Giovanna E., Sanzone, Aja, Tilahun, Kedamawit, Jiang, Chuancang, Tse, Longping V., Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Cronin, Kenneth, Gee-Lai, Victoria, Deyton, Margaret, Barr, Maggie, Von Holle, Tarra, Macintyre, Andrew N., Stover, Erica, Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Scobey, Trevor D., Rountree, Wes, Wang, Yunfei, Moody, M. Anthony, Cain, Derek W., DeMarco, C. Todd, Denny, Thomas N., Woods, Christopher W., Petzold, Elizabeth W., Schmidt, Aaron G., Teng, I-Ting, Zhou, Tongqing, Kwong, Peter D., Mascola, John R., Graham, Barney S., Moore, Ian N., Seder, Robert, Andersen, Hanne, Lewis, Mark G., Montefiori, David C., Sempowski, Gregory D., Baric, Ralph S., Acharya, Priyamvada, Haynes, Barton F., Saunders, Kevin O.

“…SARS-CoV-2-neutralizing antibodies (NAbs) protect against COVID-19. A concern regarding SARS-CoV-2 antibodies is whether they mediate disease enhancement…”
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A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization by Singh, Tulika, Hwang, Kwan-Ki, Miller, Andrew S., Jones, Rebecca L., Lopez, Cesar A., Dulson, Sarah J., Giuberti, Camila, Gladden, Morgan A., Miller, Itzayana, Webster, Helen S., Eudailey, Joshua A., Luo, Kan, Von Holle, Tarra, Edwards, Robert J., Valencia, Sarah, Burgomaster, Katherine E., Zhang, Summer, Mangold, Jesse F., Tu, Joshua J., Dennis, Maria, Alam, S. Munir, Premkumar, Lakshmanane, Dietze, Reynaldo, Pierson, Theodore C., Ooi, Eng Eong, Lazear, Helen M., Kuhn, Richard J., Permar, Sallie R., Bonsignori, Mattia

“…Congenital Zika virus (ZIKV) infection results in neurodevelopmental deficits in up to 14% of infants born to ZIKV-infected mothers. Neutralizing antibodies…”
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Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide by Alam, S Munir, Aussedat, Baptiste, Vohra, Yusuf, Meyerhoff, R Ryan, Cale, Evan M, Walkowicz, William E, Radakovich, Nathan A, Anasti, Kara, Armand, Lawrence, Parks, Robert, Sutherland, Laura, Scearce, Richard, Joyce, M Gordon, Pancera, Marie, Druz, Aliaksandr, Georgiev, Ivelin S, Von Holle, Tarra, Eaton, Amanda, Fox, Christopher, Reed, Steven G, Louder, Mark, Bailer, Robert T, Morris, Lynn, Abdool-Karim, Salim S, Cohen, Myron, Liao, Hua-Xin, Montefiori, David C, Park, Peter K, Fernández-Tejada, Alberto, Wiehe, Kevin, Santra, Sampa, Kepler, Thomas B, Saunders, Kevin O, Sodroski, Joseph, Kwong, Peter D, Mascola, John R, Bonsignori, Mattia, Moody, M Anthony, Danishefsky, Samuel, Haynes, Barton F

“…A goal for an HIV-1 vaccine is to overcome virus variability by inducing broadly neutralizing antibodies (bnAbs). One key target of bnAbs is the…”
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Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission by Permar, Sallie R, Fong, Youyi, Vandergrift, Nathan, Fouda, Genevieve G, Gilbert, Peter, Parks, Robert, Jaeger, Frederick H, Pollara, Justin, Martelli, Amanda, Liebl, Brooke E, Lloyd, Krissey, Yates, Nicole L, Overman, R Glenn, Shen, Xiaoying, Whitaker, Kaylan, Chen, Haiyan, Pritchett, Jamie, Solomon, Erika, Friberg, Emma, Marshall, Dawn J, Whitesides, John F, Gurley, Thaddeus C, Von Holle, Tarra, Martinez, David R, Cai, Fangping, Kumar, Amit, Xia, Shi-Mao, Lu, Xiaozhi, Louzao, Raul, Wilkes, Samantha, Datta, Saheli, Sarzotti-Kelsoe, Marcella, Liao, Hua-Xin, Ferrari, Guido, Alam, S Munir, Montefiori, David C, Denny, Thomas N, Moody, M Anthony, Tomaras, Georgia D, Gao, Feng, Haynes, Barton F

“…Despite the wide availability of antiretroviral drugs, more than 250,000 infants are vertically infected with HIV-1 annually, emphasizing the need for…”
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Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates by Saunders, Kevin O., Nicely, Nathan I., Wiehe, Kevin, Bonsignori, Mattia, Meyerhoff, R. Ryan, Parks, Robert, Walkowicz, William E., Aussedat, Baptiste, Wu, Nelson R., Cai, Fangping, Vohra, Yusuf, Park, Peter K., Eaton, Amanda, Go, Eden P., Sutherland, Laura L., Scearce, Richard M., Barouch, Dan H., Zhang, Ruijun, Von Holle, Tarra, Overman, R. Glenn, Anasti, Kara, Sanders, Rogier W., Moody, M. Anthony, Kepler, Thomas B., Korber, Bette, Desaire, Heather, Santra, Sampa, Letvin, Norman L., Nabel, Gary J., Montefiori, David C., Tomaras, Georgia D., Liao, Hua-Xin, Alam, S. Munir, Danishefsky, Samuel J., Haynes, Barton F.

“…Induction of broadly neutralizing antibodies (bnAbs) that target HIV-1 envelope (Env) is a goal of HIV-1 vaccine development. A bnAb target is the Env third…”
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Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques by Luo, Kan, Liao, Hua-Xin, Zhang, Ruijun, Easterhoff, David, Wiehe, Kevin, Gurley, Thaddeus C, Armand, Lawrence C, Allen, Ashley A, Von Holle, Tarra A, Marshall, Dawn J, Whitesides, John F, Pritchett, Jamie, Foulger, Andrew, Hernandez, Giovanna, Parks, Robert, Lloyd, Krissey E, Stolarchuk, Christina, Sawant, Sheetal, Peel, Jessica, Yates, Nicole L, Dunford, Erika, Arora, Sabrina, Wang, Amy, Bowman, Cindy M, Sutherland, Laura L, Scearce, Richard M, Xia, Shi-Mao, Bonsignori, Mattia, Pollara, Justin, Edwards, R Whitney, Santra, Sampa, Letvin, Norman L, Tartaglia, James, Francis, Donald, Sinangil, Faruk, Lee, Carter, Kaewkungwal, Jaranit, Nitayaphan, Sorachai, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Michael, Nelson L, Kim, Jerome H, Alam, S Munir, Vandergrift, Nathan A, Ferrari, Guido, Montefiori, David C, Tomaras, Georgia D, Haynes, Barton F, Moody, M Anthony

“…The ALVAC prime/ALVAC + AIDSVAX B/E boost RV144 vaccine trial induced an estimated 31% efficacy in a low-risk cohort where HIV‑1 exposures were likely at…”
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Eliminating antibody polyreactivity through addition of N‐linked glycosylation by Chuang, Gwo‐Yu, Zhang, Baoshan, McKee, Krisha, O'Dell, Sijy, Kwon, Young Do, Zhou, Tongqing, Blinn, Julie, Lloyd, Krissey, Parks, Robert, Von Holle, Tarra, Ko, Sung‐Youl, Kong, Wing‐Pui, Pegu, Amarendra, Wang, Keyun, Baruah, Kavitha, Crispin, Max, Mascola, John R., Moody, M. Anthony, Haynes, Barton F., Georgiev, Ivelin S., Kwong, Peter D.

“…ABSTRACT Antibody polyreactivity can be an obstacle to translating a candidate antibody into a clinical product. Standard tests such as antibody binding to…”
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Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth by Huang, Jinghe, Kang, Byong H., Ishida, Elise, Zhou, Tongqing, Griesman, Trevor, Sheng, Zizhang, Wu, Fan, Doria-Rose, Nicole A., Zhang, Baoshan, McKee, Krisha, O’Dell, Sijy, Chuang, Gwo-Yu, Druz, Aliaksandr, Georgiev, Ivelin S., Schramm, Chaim A., Zheng, Anqi, Joyce, M. Gordon, Asokan, Mangaiarkarasi, Ransier, Amy, Darko, Sam, Migueles, Stephen A., Bailer, Robert T., Louder, Mark K., Alam, S. Munir, Parks, Robert, Kelsoe, Garnett, Von Holle, Tarra, Haynes, Barton F., Douek, Daniel C., Hirsch, Vanessa, Seaman, Michael S., Shapiro, Lawrence, Mascola, John R., Kwong, Peter D., Connors, Mark

“…Detailed studies of the broadly neutralizing antibodies (bNAbs) that underlie the best available examples of the humoral immune response to HIV are providing…”
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