Search Results - "Von Feilitzen, Kalle"
-
1
A pathology atlas of the human cancer transcriptome
Published in Science (American Association for the Advancement of Science) (18-08-2017)“…Cancer is one of the leading causes of death, and there is great interest in understanding the underlying molecular mechanisms involved in the pathogenesis and…”
Get full text
Journal Article -
2
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells
Published in Science (American Association for the Advancement of Science) (20-12-2019)“…Blood is the predominant source for molecular analyses in humans, both in clinical and research settings. It is the target for many therapeutic strategies,…”
Get full text
Journal Article -
3
An atlas of the protein-coding genes in the human, pig, and mouse brain
Published in Science (American Association for the Advancement of Science) (06-03-2020)“…The brain, with its diverse physiology and intricate cellular organization, is the most complex organ of the mammalian body. To expand our basic understanding…”
Get full text
Journal Article -
4
A single-cell type transcriptomics map of human tissues
Published in Science advances (2021)“…Advances in molecular profiling have opened up the possibility to map the expression of genes in cells, tissues, and organs in the human body. Here, we…”
Get full text
Journal Article -
5
Enhanced validation of antibodies for research applications
Published in Nature communications (08-10-2018)“…There is a need for standardized validation methods for antibody specificity and selectivity. Recently, five alternative validation pillars were proposed to…”
Get full text
Journal Article -
6
The neuropeptide landscape of human prefrontal cortex
Published in Proceedings of the National Academy of Sciences - PNAS (16-08-2022)“…Human prefrontal cortex (hPFC) is a complex brain region involved in cognitive and emotional processes and several psychiatric disorders. Here, we present an…”
Get full text
Journal Article -
7
Systematic transcriptional analysis of human cell lines for gene expression landscape and tumor representation
Published in Nature communications (05-09-2023)“…Cell lines are valuable resources as model for human biology and translational medicine. It is thus important to explore the concordance between the expression…”
Get full text
Journal Article -
8
Next generation pan-cancer blood proteome profiling using proximity extension assay
Published in Nature communications (18-07-2023)“…A comprehensive characterization of blood proteome profiles in cancer patients can contribute to a better understanding of the disease etiology, resulting in…”
Get full text
Journal Article -
9
High throughput generation of a resource of the human secretome in mammalian cells
Published in New biotechnology (25-09-2020)“…•A high-throughput pipeline for production of the human secretome in mammalian cells has been set up.•Almost 1,300 proteins have successfully been produced and…”
Get full text
Journal Article -
10
Genome-wide annotation of protein-coding genes in pig
Published in BMC biology (25-01-2022)“…There is a need for functional genome-wide annotation of the protein-coding genes to get a deeper understanding of mammalian biology. Here, a new annotation…”
Get full text
Journal Article -
11
Contribution of Antibody-based Protein Profiling to the Human Chromosome-centric Proteome Project (C-HPP)
Published in Journal of proteome research (07-06-2013)“…A gene-centric Human Proteome Project has been proposed to characterize the human protein-coding genes in a chromosome-centered manner to understand human…”
Get full text
Journal Article -
12
Tissue-based map of the human proteome
Published in Science (American Association for the Advancement of Science) (23-01-2015)“…Sequencing the human genome gave new insights into human biology and disease. However, the ultimate goal is to understand the dynamic expression of each of the…”
Get full text
Journal Article -
13
Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics
Published in Molecular & cellular proteomics (01-02-2014)“…Global classification of the human proteins with regards to spatial expression patterns across organs and tissues is important for studies of human biology and…”
Get full text
Journal Article -
14
The ELIXIR Core Data Resources: fundamental infrastructure for the life sciences
Published in Bioinformatics (15-04-2020)“…Abstract Supplementary information Supplementary data are available at Bioinformatics online…”
Get full text
Journal Article -
15
A human adipose tissue cell-type transcriptome atlas
Published in Cell reports (Cambridge) (2022)“…The importance of defining cell-type-specific genes is well acknowledged. Technological advances facilitate high-resolution sequencing of single cells, but…”
Get full text
Journal Article -
16
Global compositional and functional states of the human gut microbiome in health and disease
Published in Genome research (01-06-2024)“…The human gut microbiota is of increasing interest, with metagenomics a key tool for analyzing bacterial diversity and functionality in health and disease…”
Get full text
Journal Article -
17
ANTIBODYPEDIA: THE WIKI OF ANTIBODIES
Published in Molecular biology of the cell (2016)Get full text
Journal Article -
18
Global compositional and functional states of the human gut microbiome in health and disease
Published in Genome research (01-06-2024)“…The human gut microbiota is of increasing interest, with metagenomics a key tool for analyzing bacterial diversity and functionality in health and disease…”
Get full text
Journal Article -
19
Enhanced Validation of Antibodies Enables the Discovery of Missing Proteins
Published in Journal of proteome research (04-12-2020)“…The localization of proteins at a tissue- or cell-type-specific level is tightly linked to the protein function. To better understand each protein’s role in…”
Get full text
Journal Article -
20
Antibodypedia - The wiki of antibodies
Published in Molecular biology of the cell (2015)Get full text
Journal Article