Search Results - "Von Deylen, Alison"
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Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets
Published in Proceedings of the National Academy of Sciences - PNAS (02-03-2021)“…We evaluated the potential for a monoclonal antibody antagonist of the glucagon receptor (Ab-4) to maintain glucose homeostasis in type 1 diabetic rodents. We…”
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Journal Article -
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Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation
Published in Cell metabolism (06-06-2017)“…Decreasing glucagon action lowers the blood glucose and may be useful therapeutically for diabetes. However, interrupted glucagon signaling leads to α cell…”
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Journal Article