Search Results - "Von Delft, F"

A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process by Noske, G.D., Nakamura, A.M., Gawriljuk, V.O., Fernandes, R.S., Lima, G.M.A., Rosa, H.V.D., Pereira, H.D., Zeri, A.C.M., Nascimento, A.F.Z., Freire, M.C.L.C., Fearon, D., Douangamath, A., von Delft, F., Oliva, G., Godoy, A.S.

“…[Display omitted] •Crystal structure of the immature form of Mpro (1.6A).•Immature form of Mpro in complex with 5 fragments.•Crystal structure of Mpro C145S…”
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The crystal structure of human GLRX5: iron-sulfur cluster co-ordination, tetrameric assembly and monomer activity by Johansson, Catrine, Roos, Annette K, Montano, Sergio J, Sengupta, Rajib, Filippakopoulos, Panagis, Guo, Kunde, von Delft, Frank, Holmgren, Arne, Oppermann, Udo, Kavanagh, Kathryn L

“…Human GLRX5 (glutaredoxin 5) is an evolutionarily conserved thiol-disulfide oxidoreductase that has a direct role in the maintenance of normal cytosolic and…”
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WONKA: objective novel complex analysis for ensembles of protein–ligand structures by Bradley, A. R., Wall, I. D., von Delft, F., Green, D. V. S., Deane, C. M., Marsden, B. D.

“…WONKA is a tool for the systematic analysis of an ensemble of protein–ligand structures. It makes the identification of conserved and unusual features within…”
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Status of the crystallography beamlines at Diamond Light Source by Allan, D. R., Collins, S. P., Evans, G., Hall, D., McAuley, K., Owen, R. L., Sorensen, T., Tang, C. C., von Delft, F., Wagner, A., Wilhelm, H.

“…X-ray crystallography is one of the most widely supported areas of science at Diamond Light Source and is the core technique on a third of the beamlines,…”
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Crystal Structure of Escherichia coli Ketopantoate Reductase at 1.7 Å Resolution and Insight into the Enzyme Mechanism by Matak-Vinković, Dijana, Vinković, Mladen, Saldanha, S. Adrian, Ashurst, Jennifer L, von Delft, Frank, Inoue, Tsuyoshi, Miguel, Ricardo Nunez, Smith, Alison G, Blundell, Tom L, Abell, Chris

“…Ketopantoate reductase (KPR, EC 1.1.1.169) catalyzes the NADPH-dependent reduction of ketopantoate to pantoate on the pantothenate (vitamin B5) biosynthetic…”
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A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process : SARS-CoV-2 Mpro maturation by Noske, G. D., Nakamura, A. M., Gawriljuk, V. O., Fernandes, R. S., Lima, G. M.A., Rosa, H. V.D., Pereira, H. D., Zeri, A. C.M., Nascimento, A. F.Z., Freire, M. C.L.C., Fearon, D., Douangamath, A., von Delft, F., Oliva, G., Godoy, A. S.

“…SARS-CoV-2 is the causative agent of COVID-19. The dimeric form of the viral Mpro is responsible for the cleavage of the viral polyprotein in 11 sites,…”
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Target 2035 - update on the quest for a probe for every protein by Müller, Susanne, Ackloo, Suzanne, Al Chawaf, Arij, Al-Lazikani, Bissan, Antolin, Albert, Baell, Jonathan B, Beck, Hartmut, Beedie, Shaunna, Betz, Ulrich A K, Bezerra, Gustavo Arruda, Brennan, Paul E, Brown, David, Brown, Peter J, Bullock, Alex N, Carter, Adrian J, Chaikuad, Apirat, Chaineau, Mathilde, Ciulli, Alessio, Collins, Ian, Dreher, Jan, Drewry, David, Edfeldt, Kristina, Edwards, Aled M, Egner, Ursula, Frye, Stephen V, Fuchs, Stephen M, Hall, Matthew D, Hartung, Ingo V, Hillisch, Alexander, Hitchcock, Stephen H, Homan, Evert, Kannan, Natarajan, Kiefer, James R, Knapp, Stefan, Kostic, Milka, Kubicek, Stefan, Leach, Andrew R, Lindemann, Sven, Marsden, Brian D, Matsui, Hisanori, Meier, Jordan L, Merk, Daniel, Michel, Maurice, Morgan, Maxwell R, Mueller-Fahrnow, Anke, Owen, Dafydd R, Perry, Benjamin G, Rosenberg, Saul H, Saikatendu, Kumar Singh, Schapira, Matthieu, Scholten, Cora, Sharma, Sujata, Simeonov, Anton, Sundström, Michael, Superti-Furga, Giulio, Todd, Matthew H, Tredup, Claudia, Vedadi, Masoud, von Delft, Frank, Willson, Timothy M, Winter, Georg E, Workman, Paul, Arrowsmith, Cheryl H

“…Twenty years after the publication of the first draft of the human genome, our knowledge of the human proteome is still fragmented. The challenge of…”
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Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking by Schuller, Marion, Correy, Galen J, Gahbauer, Stefan, Fearon, Daren, Wu, Taiasean, Díaz, Roberto Efraín, Young, Iris D, Carvalho Martins, Luan, Smith, Dominique H, Schulze-Gahmen, Ursula, Owens, Tristan W, Deshpande, Ishan, Merz, Gregory E, Thwin, Aye C, Biel, Justin T, Peters, Jessica K, Moritz, Michelle, Herrera, Nadia, Kratochvil, Huong T, Aimon, Anthony, Bennett, James M, Brandao Neto, Jose, Cohen, Aina E, Dias, Alexandre, Douangamath, Alice, Dunnett, Louise, Fedorov, Oleg, Ferla, Matteo P, Fuchs, Martin R, Gorrie-Stone, Tyler J, Holton, James M, Johnson, Michael G, Krojer, Tobias, Meigs, George, Powell, Ailsa J, Rack, Johannes Gregor Matthias, Rangel, Victor L, Russi, Silvia, Skyner, Rachael E, Smith, Clyde A, Soares, Alexei S, Wierman, Jennifer L, Zhu, Kang, O'Brien, Peter, Jura, Natalia, Ashworth, Alan, Irwin, John J, Thompson, Michael C, Gestwicki, Jason E, von Delft, Frank, Shoichet, Brian K, Fraser, James S, Ahel, Ivan

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) macrodomain within the nonstructural protein 3 counteracts host-mediated antiviral adenosine…”
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Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin by Blundell, Tom L, Pellegrini, Luca, Burke, David F, von Delft, Frank, Mulloy, Barbara

“…Fibroblast growth factors (FGFs) are a large family of structurally related proteins with a wide range of physiological and pathological activities. Signal…”
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Setting high-resolution limits for anisotropic data by Vollmar, M., Murshudov, G., von Delft, F.

“…Abstract only…”
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The Crystal Structure of E. coli Pantothenate Synthetase Confirms It as a Member of the Cytidylyltransferase Superfamily by von Delft, Frank, Lewendon, Ann, Dhanaraj, Venugopal, Blundell, Tom L., Abell, Chris, Smith, Alison G.

“…Background: Pantothenate synthetase (EC 6.3.2.1) is the last enzyme of the pathway of pantothenate (vitamin B 5) synthesis. It catalyzes the condensation of…”
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The Crystal Structure of Shikimate Dehydrogenase (AroE) Reveals a Unique NADPH Binding Mode by Ye, Sheng, Von Delft, Frank, Brooun, Alexei, Knuth, Mark W, Swanson, Ronald V, McRee, Duncan E

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Structure of E. coli ketopantoate hydroxymethyl transferase complexed with ketopantoate and Mg2+, solved by locating 160 selenomethionine sites by von Delft, Frank, Inoue, Tsuyoshi, Saldanha, S Adrian, Ottenhof, Harald H, Schmitzberger, Florian, Birch, Louise M, Dhanaraj, Venugopal, Witty, Michael, Smith, Alison G, Blundell, Tom L, Abell, Chris

“…We report the crystal structure of E. coli ketopantoate hydroxymethyltransferase (KPHMT) at 1.9 A resolution, in complex with its product, ketopantoate. KPHMT…”
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XDX – an initial solution to crystallization by Newman, J., Snell, E. H., Luft, J., von Delft, F., Müller-Dieckmann, J., Taylor, K., Ratcliffe, D., Fazio, V. J.

“…Abstract only…”
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Two-wavelength MAD phasing and radiation damage: a case study by González, Ana, von Delft, Frank, Liddington, Robert C, Bakolitsa, Constantina

“…Radiation damage affects MAD experiments in two ways: (i) increased absorption by the crystal at the wavelengths of interest for the experiment results in…”
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Crystal structure of a PIN (PilT N-terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 Å resolution by Levin, Inna, Schwarzenbacher, Robert, Page, Rebecca, Abdubek, Polat, Ambing, Eileen, Biorac, Tanya, Brinen, Linda S., Campbell, Jamison, Canaves, Jaume M., Chiu, Hsiu-Ju, Dai, Xiaoping, Deacon, Ashley M., DiDonato, Mike, Elsliger, Marc-André, Floyd, Ross, Godzik, Adam, Grittini, Carina, Grzechnik, Slawomir K., Hampton, Eric, Jaroszewski, Lukasz, Karlak, Cathy, Klock, Heath E., Koesema, Eric, Kovarik, John S., Kreusch, Andreas, Kuhn, Peter, Lesley, Scott A., McMullan, Daniel, McPhillips, Timothy M., Miller, Mitchell D., Morse, Andrew, Moy, Kin, Ouyang, Jie, Quijano, Kevin, Reyes, Ron, Rezezadeh, Fred, Robb, Alyssa, Sims, Eric, Spraggon, Glen, Stevens, Raymond C., van den Bedem, Henry, Velasquez, Jeff, Vincent, Juli, von Delft, Frank, Wang, Xianhong, West, Bill, Wolf, Guenter, Xu, Qingping, Hodgson, Keith O., Wooley, John, Wilson, Ian A.

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Optimizing signal-to-noise on a home X-ray source for the analysis of microcrystals by Frankel, D.C., Lancaster, R., Michell, B., Storm, A., Burkholder, R., von Delft, F., Murray, J.

“…Abstract only…”
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A family-wide approach to structure-based inhibitor design for protein tyrosine phosphatases by Roos, A.K., Barr, A.J., King, O., Ugochukwu, E., Russell, A., Knapp, S., von Delft, F.

“…Abstract only…”
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Structural genomics on human kinases at SGC Oxford by Debreczeni, J. É., Knapp, S., von Delft, F., Sundstrom, M.

“…Abstract only…”
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Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 Å resolution by Heine, Andreas, Canaves, Jaume M., von Delft, Frank, Brinen, Linda S., Dai, Xiaoping, Deacon, Ashley M., Elsliger, Marc A., Eshaghi, Said, Floyd, Ross, Godzik, Adam, Grittini, Carina, Grzechnik, Slawomir K., Guda, Chittibabu, Jaroszewski, Lukasz, Karlak, Cathy, Klock, Heath E., Koesema, Eric, Kovarik, John S., Kreusch, Andreas, Kuhn, Peter, Lesley, Scott A., McMullan, Daniel, McPhillips, Timothy M., Miller, Mark A., Miller, Mitchell D., Morse, Andrew, Moy, Kin, Ouyang, Jie, Page, Rebecca, Robb, Alyssa, Rodrigues, Kevin, Schwarzenbacher, Robert, Selby, Thomas L., Spraggon, Glen, Stevens, Raymond C., van den Bedem, Henry, Velasquez, Jeff, Vincent, Juli, Wang, Xianhong, West, Bill, Wolf, Guenter, Hodgson, Keith O., Wooley, John, Wilson, Ian A.

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