Search Results - "Vom Saal, Frederick"

Update on the Health Effects of Bisphenol A: Overwhelming Evidence of Harm by vom Saal, Frederick S, Vandenberg, Laura N

“…In 1997, the first in vivo bisphenol A (BPA) study by endocrinologists reported that feeding BPA to pregnant mice induced adverse reproductive effects in male…”
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Large Effects from Small Exposures. III. Endocrine Mechanisms Mediating Effects of Bisphenol A at Levels of Human Exposure by Welshons, Wade V, Nagel, Susan C, vom Saal, Frederick S

“…Over 6 billion pounds per year of the estrogenic monomer bisphenol A (BPA) are used to manufacture polycarbonate plastic products, in resins lining metal cans,…”
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Holding thermal receipt paper and eating food after using hand sanitizer results in high serum bioactive and urine total levels of bisphenol A (BPA) by Hormann, Annette M, Vom Saal, Frederick S, Nagel, Susan C, Stahlhut, Richard W, Moyer, Carol L, Ellersieck, Mark R, Welshons, Wade V, Toutain, Pierre-Louis, Taylor, Julia A

“…Bisphenol A (BPA) is an endocrine disrupting environmental contaminant used in a wide variety of products, and BPA metabolites are found in almost everyone's…”
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Similarity of Bisphenol A Pharmacokinetics in Rhesus Monkeys and Mice: Relevance for Human Exposure by Taylor, Julia A., vom Saal, Frederick S., Welshons, Wade V., Drury, Bertram, Rottinghaus, George, Hunt, Patricia A., Toutain, Pierre-Louis, Laffont, Céline M., VandeVoort, Catherine A.

“…Objective: Daily adult human exposure to bisphenol A (BPA) has been estimated at < 1 μg/kg, with virtually complete first-pass conjugation in the liver in…”
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Conjugated bisphenol A in maternal serum in relation to miscarriage risk by Lathi, Ruth B., M.D, Liebert, Cara A., M.D, Brookfield, Kathleen F., M.D., Ph.D., M.P.H, Taylor, Julia A., Ph.D, vom Saal, Frederick S., Ph.D, Fujimoto, Victor Y., M.D, Baker, Valerie L., M.D

“…Objective To examine the relationship between the maternal serum bisphenol A (BPA) concentration at the time of the missed menstrual cycle and miscarriage…”
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The estrogenic endocrine disrupting chemical bisphenol A (BPA) and obesity by vom Saal, Frederick S., Nagel, Susan C., Coe, Benjamin L., Angle, Brittany M., Taylor, Julia A.

“…► Estrogenic EDC exposure may lead to obesity via genetic programming. ► Estrogens and EDCs directly regulate adipocyte function. ► Developmental EDC exposure…”
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Our plastic age by Thompson, Richard C., Swan, Shanna H., Moore, Charles J., vom Saal, Frederick S.

“…Philosophical Transactions of the Royal Society…”
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Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses by Vandenberg, Laura N, Colborn, Theo, Hayes, Tyrone B, Heindel, Jerrold J, Jacobs, David R, Lee, Duk-Hee, Shioda, Toshi, Soto, Ana M, vom Saal, Frederick S, Welshons, Wade V, Zoeller, R. Thomas, Myers, John Peterson

“…For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional concepts in toxicology, in particular the dogma of “the dose makes…”
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The effects of bisphenol A on emotional behavior depend upon the timing of exposure, age and gender in mice by Gioiosa, Laura, Parmigiani, Stefano, vom Saal, Frederick S., Palanza, Paola

“…Experimental evidence suggests that endocrine-disrupting chemicals (EDCs) can permanently disrupt the development of sexually dimorphic behaviors and the…”
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Should oral gavage be abandoned in toxicity testing of endocrine disruptors? by Vandenberg, Laura N, Welshons, Wade V, Vom Saal, Frederick S, Toutain, Pierre-Louis, Myers, John Peterson

“…For decades, hazard assessments for environmental chemicals have used intra-gastric gavage to assess the effects of 'oral' exposures. It is now widely…”
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Plastics, the environment and human health: current consensus and future trends by Thompson, Richard C., Moore, Charles J., vom Saal, Frederick S., Swan, Shanna H.

“…Plastics have transformed everyday life; usage is increasing and annual production is likely to exceed 300 million tonnes by 2010. In this concluding paper to…”
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Effects of the environmental estrogenic contaminants bisphenol A and 17α-ethinyl estradiol on sexual development and adult behaviors in aquatic wildlife species by Bhandari, Ramji K, Deem, Sharon L, Holliday, Dawn K, Jandegian, Caitlin M, Kassotis, Christopher D, Nagel, Susan C, Tillitt, Donald E, vom Saal, Frederick S, Rosenfeld, Cheryl S

“…Highlights • Bisphenol A (BPA) and ethinyl estradiol (EE2) are detectable in various aquatic sources. • BPA and EE2 can disrupt sexual differentiation in…”
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BPA: have flawed analytical techniques compromised risk assessments? by Gerona, Roy, vom Saal, Frederick S, Hunt, Patricia A

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An Extensive New Literature concerning Low-Dose Effects of Bisphenol A Shows the Need for a New Risk Assessment by Frederick S. vom Saal, Hughes, Claude

“…Bisphenol A (BPA) is the monomer used to manufacture polycarbonate plastic, the resin lining of cans, and other products, with global capacity in excess of 6.4…”
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Minireview: Endocrine Disruptors: Past Lessons and Future Directions by Schug, Thaddeus T, Johnson, Anne F, Birnbaum, Linda S, Colborn, Theo, Guillette, Louis J, Crews, David P, Collins, Terry, Soto, Ana M, vom Saal, Frederick S, McLachlan, John A, Sonnenschein, Carlos, Heindel, Jerrold J

“…Within the past few decades, the concept of endocrine-disrupting chemicals (EDCs) has risen from a position of total obscurity to become a focus of dialogue,…”
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Interactive Effects of Perinatal BPA or DES and Adult Testosterone and Estradiol Exposure on Adult Urethral Obstruction and Bladder, Kidney, and Prostate Pathology in Male Mice by Taylor, Julia A, Jones, Maren Bell, Besch-Williford, Cynthia L, Berendzen, Ashley F, Ricke, William A, S Vom Saal, Frederick

“…Obstructive voiding disorder (OVD) occurs during aging in men and is often, but not always, associated with increased prostate size, due to benign prostatic…”
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Bisphenol A and Risk of Metabolic Disorders by vom Saal, Frederick S, Myers, John Peterson

“…Saal and Myers comment on Lang and colleagues' report about the results of the first major epidemiologic study, which examines the health effects associated…”
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Non-monotonic dose effects of in utero exposure to di(2-ethylhexyl) phthalate (DEHP) on testicular and serum testosterone and anogenital distance in male mouse fetuses by Do, Rylee Phuong, Stahlhut, Richard W., Ponzi, Davide, vom Saal, Frederick S., Taylor, Julia A.

“…► DEHP is reported to alter male fetus masculinization and reduce anogenital distance. ► Most studies are of high-dose effects, beyond human exposure levels. ►…”
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Components of plastic: experimental studies in animals and relevance for human health by Talsness, Chris E., Andrade, Anderson J. M., Kuriyama, Sergio N., Taylor, Julia A., vom Saal, Frederick S.

“…Components used in plastics, such as phthalates, bisphenol A (BPA), polybrominated diphenyl ethers (PBDE) and tetrabromobisphenol A (TBBPA), are detected in…”
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Serum unconjugated bisphenol A concentrations in women may adversely influence oocyte quality during in vitro fertilization by Fujimoto, Victor Y., M.D, Kim, Dongsul, B.S, vom Saal, Frederick S., Ph.D, Lamb, Julie D., M.D, Taylor, Julia A., Ph.D, Bloom, Michael S., Ph.D

“…Bisphenol A (BPA) is an endocrine disruptor with estrogenic properties that can adversely affect meiotic spindle assemblies. Our data indicate that BPA…”
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