Search Results - "Volpe, Filippo"
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Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor
Published in Nature cell biology (01-06-2000)“…Interleukin-1 (IL-1) is a proinflammatory cytokine that elicits its pleiotropic effects through activation of the transcription factors NF-kappaB and AP-1…”
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Identification of Threonine 66 as a Functionally Critical Residue of the Interleukin-1 Receptor-associated Kinase
Published in The Journal of biological chemistry (04-10-2002)“…We have mutated a conserved residue of the death domain of the interleukin-1 (IL-1) receptor-associated kinase (IRAK), threonine 66. The substitution of Thr-66…”
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Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-κB
Published in Biochemical journal (15-04-1999)Get full text
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The E. coli cAMP receptor protein can be used in a eukaryotic system as a repressor activated by cAMP
Published in Biochemical Society transactions (01-05-1997)Get more information
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The IL1 receptor accessory protein is responsible for the recruitment of the interleukin-1 receptor associated kinase to the IL1/IL1 receptor I complex
Published in FEBS letters (08-12-1997)“…Following interleukin-1 (IL1) stimulation, an IL1 receptor associated kinase (IRAK) is rapidly recruited to the receptor complex. However, it is not understood…”
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Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-κB
Published in Biochemical journal (15-04-1999)“…Upon interleukin 1 (IL-1) stimulation, the IL-1-receptor (IL-1R)-associated kinase (IRAK) is rapidly recruited to the IL-1R complex and undergoes…”
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Isolation and molecular characterization of the bifunctional hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase gene from Toxoplasma gondii
Published in Molecular and biochemical parasitology (01-05-1997)“…Toxoplasma gondii is an important cause of AIDS-related opportunistic infection, manifest as toxoplasmic encephalitis. The clinical treatment of choice is the…”
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Two domains with amino-acid sequence similarity are required for dihydroneopterin aldolase function in the multifunctional folic acid synthesis fas protein of Pneumocystis carinii
Published in Gene (04-07-1995)“…The folic acid synthesized gene ( fas) of Pneumocystis carinii (Pc) codes for a multifunctional enzyme (Fas) known to catalyse three consecutive steps leading…”
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Isolation and molecular characterization of the bifunctional hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase gene from Toxoplasma gondii1Note: Nucleotide sequence data reported in this paper are available in the EMBL, GenBank and DDJB databases under the accession number U81497.1
Published in Molecular and biochemical parasitology (01-05-1997)Get full text
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Molecular characterization and localization of human metabotropic glutamate receptor type 3
Published in Brain research. Molecular brain research. (01-08-1996)“…A human brain cDNA library was screened using amplified human metabotropic glutamate receptor (mGluR) cDNA sequences as probes. The resulting clones included…”
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The multifunctional folic acid synthesis fas gene of Pneumocystis carinii encodes dihydroneopterin aldolase, hydroxymethyldihydropterin pyrophosphokinase and dihydropteroate synthase
Published in European journal of biochemistry (01-09-1993)“…The nucleotide sequence of a folic acid synthesis (fas) gene from Pneumocystis carinii contains an open reading frame (ORF) that predicts a protein of 740…”
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