Search Results - "Volovikov, Egor A"
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Cortical neurons obtained from patient-derived iPSCs with GNAO1 p.G203R variant show altered differentiation and functional properties
Published in Heliyon (15-03-2024)“…Pathogenic variants in the GNAO1 gene, encoding the alpha subunit of an inhibitory heterotrimeric guanine nucleotide-binding protein (Go) highly expressed in…”
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STIM2 Mediates Excessive Store-Operated Calcium Entry in Patient-Specific iPSC-Derived Neurons Modeling a Juvenile Form of Huntington's Disease
Published in Frontiers in cell and developmental biology (02-02-2021)“…Huntington's disease (HD) is a severe autosomal-dominant neurodegenerative disorder caused by a mutation within a gene, encoding huntingtin protein. Here we…”
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Specific cleavage of IGFBP-4 by papp-a in nervous tissue
Published in Biochemical and biophysical research communications (12-11-2024)“…Astrocytes are subtypes of glial cells involved in metabolic, structural, homeostatic, and neuroprotective processes that help neurons maintain viability…”
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Comparison of the calcium signaling alterations in GABA-ergic medium spiny neurons produced from iPSCs of different origins
Published in Biochimie (01-07-2024)“…Disease models based on induced pluripotent stem cells (iPSCs) are in high demand because of their physiological adequacy and well-reproducibility of the…”
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