Search Results - "Voloshchuk, Natali I"
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The Crystal Structure of N-(1-Arylethyl)-4-methyl- 2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamides as the Factor Determining Biological Activity Thereof
Published in Scientia pharmaceutica (01-04-2019)“…In order to detect new structural and biological patterns in a series of hetaryl-3-carboxylic acid derivatives, the optically pure (S)- and (R)-enantiomers of…”
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2
Synthesis and Regularities of the Structure–Activity Relationship in a Series of N-Pyridyl-4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamides
Published in Scientia pharmaceutica (15-05-2019)“…According to our quantum and chemical calculations 4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylic acid imidazolide is theoretically almost as reactive…”
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3
4-Methyl-2,2-dioxo-1H-2λ⁶,1-benzothiazine-3-carboxylic Acid. Peculiarities of Preparation, Structure, and Biological Properties
Published in Scientia pharmaceutica (08-03-2018)“…In order to determine the regularities of the structure-analgesic activity relationship, the peculiarities of obtaining, the spatial structure, and biological…”
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Synthesis, Crystal Structure, and Biological Activity of Ethyl 4-Methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylate Polymorphic Forms
Published in Scientia pharmaceutica (30-05-2018)“…The data obtained from the powder diffraction experiments were compared to the data calculated from the single crystal structures and showed clearly that both…”
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1‐Allyl‐4‐hydroxy‐2,2‐dioxo‐N‐(4‐methoxyphenyl)‐1H‐2λ6,1‐benzothiazine‐3‐carboxamide: polymorphic transition due to grinding with the loss of the biological activity
Published in Acta crystallographica Section B, Structural science, crystal engineering and materials (01-02-2022)“…A study of two polymorphic forms of 1‐allyl‐4‐hydroxy‐2,2‐dioxo‐N‐(4‐methoxyphenyl)‐1‐2λ6,1‐benzothiazine‐3‐carboxamide (a structural analogue of piroxicam)…”
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Biological properties of two enantiomorphic forms of N‐(2,6‐dimethylphenyl)‐4‐hydroxy‐2,2‐dioxo‐1H‐2λ6,1‐benzothiazine‐3‐carboxamide, a structural analogue of piroxicam
Published in Acta crystallographica. Section C, Crystal structure communications (01-01-2020)“…The title benzothiazine‐3‐carboxamide, C17H16N2O4S, crystallized in two enantiomorphic crystal forms with the space groups P32 and P31 despite the absence of a…”
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7
Crystal Habits and Biological Properties of N-(4-Trifluoromethylphenyl)-4-Hydroxy-2,2-Dioxo-1H-2λ6,1-Benzothiazine-3-Carboxamide
Published in Scientia pharmaceutica (01-01-2020)“…In order to study polymorphic modifications of N-(4-trifluoromethylphenyl)-4-hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamide, which is of interest as a…”
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8
1-Allyl-4-hydroxy-2,2-dioxo- N -(4-methoxyphenyl)-1 H -2λ 6 ,1-benzothiazine-3-carboxamide: polymorphic transition due to grinding with the loss of the biological activity
Published in Acta crystallographica Section B, Structural science, crystal engineering and materials (01-02-2022)“…A study of two polymorphic forms of 1-allyl-4-hydroxy-2,2-dioxo- N -(4-methoxyphenyl)-1-2λ 6 ,1-benzothiazine-3-carboxamide (a structural analogue of…”
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9
1-Allyl-4-hydroxy-2,2-dioxo-N-(4-methoxyphenyl)-1H-2λ 6 ,1-benzothiazine-3-carboxamide: polymorphic transition due to grinding with the loss of the biological activity
Published in Acta crystallographica Section B, Structural science, crystal engineering and materials (01-02-2022)“…A study of two polymorphic forms of 1-allyl-4-hydroxy-2,2-dioxo-N-(4-methoxyphenyl)-1-2λ ,1-benzothiazine-3-carboxamide (a structural analogue of piroxicam)…”
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10
Biological properties of two enantiomorphic forms of N -(2,6-dimethylphenyl)-4-hydroxy-2,2-dioxo-1 H -2λ 6 ,1-benzothiazine-3-carboxamide, a structural analogue of piroxicam
Published in Acta crystallographica. Section C, Structural chemistry (01-01-2020)“…The title benzothiazine-3-carboxamide, C 17 H 16 N 2 O 4 S, crystallized in two enantiomorphic crystal forms with the space groups P 3 2 and P 3 1 despite the…”
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11
Biological properties of two enantiomorphic forms of N-(2,6-dimethylphenyl)-4-hydroxy-2,2-dioxo-1H-2λ 6 ,1-benzothiazine-3-carboxamide, a structural analogue of piroxicam
Published in Acta crystallographica. Section C, Structural chemistry (01-01-2020)“…The title benzothiazine-3-carboxamide, C H N O S, crystallized in two enantiomorphic crystal forms with the space groups P3 and P3 despite the absence of a…”
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12
Molecular Conformations and Biological Activity of N-Hetaryl(aryl)alkyl-4-methyl-2,2-dioxo-1H-2λ^sup 6^, 1-benzothiazine-3-carboxamides
Published in Scientia pharmaceutica (01-10-2018)“…According to the results of the pharmacological tests carried out on the model of carrageenan inflammation it has been found that all without exception…”
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Synthesis, Crystal Structure, and Biological Activity of Ethyl 4-Methyl-2,2-dioxo-1 H -2λ⁶,1-benzothiazine-3-carboxylate Polymorphic Forms
Published in Scientia pharmaceutica (30-05-2018)“…Continuing the search for new potential analgesics among the derivatives of 4-methyl-2,2-dioxo-1 -2λ⁶,1-benzothiazine-3-carboxylic acid, the possibility of…”
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14
Molecular Conformations and Biological Activity of N-Hetaryl(aryl)alkyl-4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamides
Published in Scientia pharmaceutica (30-11-2018)“…The analysis of our previous studies on the search for synthetic analgesics among N-R-amides of bicyclic hetaryl-3-carboxylic acids has been performed; on its…”
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