Search Results - "Vollmar, B."

The dorsal skinfold chamber: window into the dynamic interaction of biomaterials with their surrounding host tissue by Laschke, M W, Vollmar, B, Menger, M D

“…The implantation of biomaterials into the human body has become an indispensable part of almost all fields of modern medicine. Accordingly, there is an…”
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PDGF-BB regulates splitting angiogenesis in skeletal muscle by limiting VEGF-induced endothelial proliferation by Gianni-Barrera, R., Butschkau, A., Uccelli, A., Certelli, A., Valente, P., Bartolomeo, M., Groppa, E., Burger, M. G., Hlushchuk, R., Heberer, M., Schaefer, D. J., Gürke, L., Djonov, V., Vollmar, B., Banfi, A.

“…VEGF induces normal or aberrant angiogenesis depending on its dose in the microenvironment around each producing cell in vivo. This transition depends on the…”
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Lifelong caloric restriction reprograms hepatic fat metabolism in mice by Kuhla, Angela, Hahn, Steffi, Butschkau, Antje, Lange, Sophie, Wree, Andreas, Vollmar, Brigitte

“…Calorie lowering slows the aging process and extends life span in diverse species by so far unknown mechanisms. The inverse linear relationship between calorie…”
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In vivo analysis of biocompatibility and vascularization of the synthetic bone grafting substitute NanoBone by Abshagen, K., Schrodi, I., Gerber, T., Vollmar, B.

“…One of the major challenges in the application of bone substitutes is adequate vascularization and biocompatibility of the implant. Thus, the temporal course…”
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Intraluminal three-dimensional optical coherence tomography - a tool for imaging of the Eustachian tube? by Schuon, R, Mrevlje, B, Vollmar, B, Lenarz, T, Paasche, G

“…The cause of Eustachian tube dysfunction often remains unclear. Therefore, this study aimed to examine the feasibility and possible diagnostic use of optical…”
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[ 18 F]-florbetaben PET/CT Imaging in the Alzheimer's Disease Mouse Model APPswe/PS1dE9 by Stenzel, J, Rühlmann, C, Lindner, T, Polei, S, Teipel, S, Kurth, J, Rominger, A, Krause, B J, Vollmar, B, Kuhla, A

“…Positron-emission-tomography (PET) using 18F labeled florbetaben allows noninvasive in vivo-assessment of amyloid-beta (Aβ), a pathological hallmark of…”
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RAGE blockade and hepatic microcirculation in experimental endotoxaemic liver failure by Kuhla, A., Norden, J., Abshagen, K., Menger, M. D., Vollmar, B.

“…Background Activation of the receptor for advanced glycation endproducts (RAGE) causes sustained activation of multiple inflammatory pathways. Therefore, RAGE…”
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Decitabine demonstrates antileukemic activity in B cell precursor acute lymphoblastic leukemia with MLL rearrangements by Roolf, C, Richter, A, Konkolefski, C, Knuebel, G, Sekora, A, Krohn, S, Stenzel, J, Krause, B J, Vollmar, B, Murua Escobar, H, Junghanss, C

“…Promotor hypermethylation of CpG islands is common in B cell precursor acute lymphoblastic leukemia (BCP-ALL) with mixed lineage leukemia (MLL) gene…”
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Small animal bone healing models: Standards, tips, and pitfalls results of a consensus meeting by Histing, T, Garcia, P, Holstein, J.H, Klein, M, Matthys, R, Nuetzi, R, Steck, R, Laschke, M.W, Wehner, T, Bindl, R, Recknagel, S, Stuermer, E.K, Vollmar, B, Wildemann, B, Lienau, J, Willie, B, Peters, A, Ignatius, A, Pohlemann, T, Claes, L, Menger, M.D

“…Abstract Small animal fracture models have gained increasing interest in fracture healing studies. To achieve standardized and defined study conditions,…”
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Paclitaxel-coated stents to prevent hyperplastic proliferation of ureteral tissue: from in vitro to in vivo by Kram, W., Rebl, H., Wyrwa, R., Laube, T., Zimpfer, A., Maruschke, M., Frank, M., Vollmar, B., Kundt, G., Schnabelrauch, M., Nebe, B., Buchholz, N., Hakenberg, O. W.

“…Ureteric stents have become an indispensable tool in the armamentarium of every urologist. However, they carry their own morbidity resulting mostly from…”
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Toll-like receptor 2-deficiency on bone marrow-derived cells augments vascular healing of murine arterial lesions by Liu, W., Eczko, J.-C., Otto, M., Bajorat, R., Vollmar, B., Roesner, J.-P., Wagner, N.-M.

“…Neointimal hyperplasia contributes to arterial restenosis after percutaneous transluminal coronary angioplasty or vascular surgery. Neointimal thickening after…”
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Diabetes aggravates acute pancreatitis and inhibits pancreas regeneration in mice by Zechner, D., Spitzner, M., Bobrowski, A., Knapp, N., Kuhla, A., Vollmar, B.

“…Aims/hypothesis It is well established that acute pancreatitis often causes diabetes and that a high blood glucose level associated with pancreatitis is a…”
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Combined inhibition of vascular endothelial growth factor (VEGF), fibroblast growth factor and platelet-derived growth factor, but not inhibition of VEGF alone, effectively suppresses angiogenesis and vessel maturation in endometriotic lesions by Laschke, M.W., Elitzsch, A., Vollmar, B., Vajkoczy, P., Menger, M.D.

“…BACKGROUND: Angiogenesis represents the crucial step in the pathogenesis of endometriosis, because endometriotic lesions require neovascularization to…”
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Epigallocatechin-3-gallate inhibits estrogen-induced activation of endometrial cells in vitro and causes regression of endometriotic lesions in vivo by Laschke, Matthias W., Schwender, Christine, Scheuer, Claudia, Vollmar, Brigitte, Menger, Michael D.

“…BACKGROUND Epigallocatechin-3-gallate (EGCG), the major component of green tea, is a pleiotropic substance, which may inhibit tumor growth via multiple…”
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Comparison of surgical stress between laparoscopic and open colonic resections by HILDEBRANDT, U, KESSLER, K, PLUSCZYK, T, PISTORIUS, G, VOLLMAR, B, MENGER, M. D

“…The magnitude of surgical trauma after laparoscopic and open colonic resection was evaluated by examining postoperative serum values of interleukin-6 (IL-6),…”
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Pathomechanisms of Ischemia-Reperfusion Injury as the Basis for Novel Preventive Strategies: Is It Time for the Introduction of Pleiotropic Compounds? by Menger, M.D, Vollmar, B

“…Abstract Ischemia-reperfusion–associated tissue dysfunction and organ failure still represent major complications in transplantation surgery. The…”
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Nitric oxide reduces organ injury and enhances regeneration of reduced-size livers by increasing hepatic arterial flow by Cantré, D., Schuett, H., Hildebrandt, A., Dold, S., Menger, M. D., Vollmar, B., Eipel, C.

“…Background: Reduced‐size livers suffer from portal hyperperfusion, diminished arterial blood flow and the risk of postoperative liver injury. The aim of this…”
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Rapamycin induces regression of endometriotic lesions by inhibiting neovascularization and cell proliferation by Laschke, M W, Elitzsch, A, Scheuer, C, Holstein, J H, Vollmar, B, Menger, M D

“…Background and purpose: Rapamycin is a widely used drug with antifungal, immunosuppressant and antiangiogenic effects. Herein, we studied whether…”
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Inhibition of p53 protects liver tissue against endotoxin‐induced apoptotic and necrotic cell death by Schäfer, T., Scheuer, C., Roemer, K., Menger, M. D., Vollmar, B.

“…ABSTRACT There is increasing evidence that apoptotic and necrotic hepatocyte death following endotoxin‐induced liver injury act as signals for leukocyte…”
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Ghrelin protects musculocutaneous tissue from ischemic necrosis by improving microvascular perfusion by Rezaeian, F, Wettstein, R, Scheuer, C, Bäumker, K, Bächle, A, Vollmar, B, Menger, M D, Harder, Y

“…Persistent ischemia in musculocutaneous tissue may lead to wound breakdown and necrosis. The objective of this experimental study was to analyze, whether the…”
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