Search Results - "Vollmar, AM"

The role of atrial natriuretic peptide in the immune system by Vollmar, Angelika M.

“…Atrial natriuretic peptide (ANP) is a hormone predominately produced by the heart atria which regulates the water and salt balance as well as blood pressure…”
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Anti‐angiogenic effects of the tubulysin precursor pretubulysin and of simplified pretubulysin derivatives by Rath, S, Liebl, J, Fürst, R, Ullrich, A, Burkhart, JL, Kazmaier, U, Herrmann, J, Müller, Rolf, Günther, M, Schreiner, L, Wagner, E, Vollmar, AM, Zahler, S

“…BACKGROUND AND PURPOSE The use of tubulin‐binding compounds, which act in part by inhibiting tumour angiogenesis, has become an integral strategy of tumour…”
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Small molecule inhibitors of the mitochondrial ClpXP protease possess cytostatic potential and re-sensitize chemo-resistant cancers by Meßner, Martina, Mandl, Melanie M., Hackl, Mathias W., Reinhardt, Till, Ardelt, Maximilian A., Szczepanowska, Karolina, Frädrich, Julian E., Waschke, Jens, Jeremias, Irmela, Fux, Anja, Stahl, Matthias, Vollmar, Angelika M., Sieber, Stephan A., Pachmayr, Johanna

“…The human mitochondrial ClpXP protease complex (HsClpXP) has recently attracted major attention as a target for novel anti-cancer therapies. Despite its…”
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Red wine polyphenols enhance endothelial nitric oxide synthase expression and subsequent nitric oxide release from endothelial cells by LEIKERT, Jürgen F, RÄTHEL, Thomas R, WOHLFART, Paulus, CHEYNIER, Véronique, VOLLMAR, Angelika M, DIRSCH, Verena M

“…Population-based studies suggest a reduced incidence of morbidity and mortality from coronary heart disease caused by moderate and regular consumption of red…”
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Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-κB pathway by Kiemer, Alexandra K, Hartung, Thomas, Huber, Christian, Vollmar, Angelika M

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Silibinin protects mice from T cell-dependent liver injury by Schümann, Jens, Prockl, Jennifer, Kiemer, Alexandra K, Vollmar, Angelika M, Bang, Renate, Tiegs, Gisa

“…Background/Aims: Silibinin is the major pharmacologically active compound of the Silybum marianum fruit extract silymarin. Its well-known hepatoprotective…”
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Flavopiridol Protects Against Inflammation by Attenuating Leukocyte-Endothelial Interaction via Inhibition of Cyclin-Dependent Kinase 9 by Schmerwitz, Ulrike K, Sass, Gabriele, Khandoga, Alexander G, Joore, Jos, Mayer, Bettina A, Berberich, Nina, Totzke, Frank, Krombach, Fritz, Tiegs, Gisa, Zahler, Stefan, Vollmar, Angelika M, Fürst, Robert

“…OBJECTIVE—The cyclin-dependent kinase (CDK) inhibitor flavopiridol is currently being tested in clinical trials as anticancer drug. Beyond its cell…”
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Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway by Müller, Christian, Dünschede, Friedrich, Koch, Elke, Vollmar, Angelika M, Kiemer, Alexandra K

“…In liver resection and transplantation ischemia-reperfusion injury (IRI) is one of the main causes of organ dys- or nonfunction. The aim of the present study…”
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Inhibition of p38 MAPK Activation via Induction of MKP-1: Atrial Natriuretic Peptide Reduces TNF-α–Induced Actin Polymerization and Endothelial Permeability by Kiemer, Alexandra K, Weber, Nina C, Fürst, Robert, Bildner, Nicole, Kulhanek-Heinze, Stefanie, Vollmar, Angelika M

“…The atrial natriuretic peptide (ANP) is a cardiovascular hormone possessing antiinflammatory potential due to its inhibitory action on the production of…”
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Atrial Natriuretic Peptide Induces Mitogen-Activated Protein Kinase Phosphatase-1 in Human Endothelial Cells via Rac1 and NAD(P)H Oxidase/Nox2-Activation by Fürst, Robert, Brueckl, Corinna, Kuebler, Wolfgang M, Zahler, Stefan, Krötz, Florian, Görlach, Agnes, Vollmar, Angelika M, Kiemer, Alexandra K

“…The cardiovascular hormone atrial natriuretic peptide (ANP) exerts anti-inflammatory effects on tumor necrosis factor-α–activated endothelial cells by inducing…”
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cGMP-mediated inhibition of TNF-alpha production by the atrial natriuretic peptide in murine macrophages by Kiemer, A K, Hartung, T, Vollmar, A M

“…The atrial natriuretic peptide (ANP) is suggested to regulate inflammatory response by alteration of macrophage functions. The aim of this study was to…”
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Atrial natriuretic peptide in lymphoid organs of various species by Vollmar, A M, Schulz, R

“…1. Evidence for the occurrence of atrial natriuretic peptide (ANP) in various lymphoid organs of different species (rat, mouse, pig, chicken) is provided. 2…”
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Inhibition of LPS-induced nitric oxide and TNF-α production by α-lipoic acid in rat Kupffer cells and in RAW 264.7 murine macrophages by Kiemer, Alexandra K, Müller, Christian, Vollmar, Angelika M

“…The activation of Kupffer cells represents a central mechanism of inflammatory liver injury involving the production of two important inflammatory mediators,…”
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Neurokinin-1 receptor antagonists CP-96,345 and L-733,060 protect mice from cytokine-mediated liver injury by Bang, Renate, Sass, Gabriele, Kiemer, Alexandra K, Vollmar, Angelika M, Neuhuber, Winfried L, Tiegs, Gisa

“…Previously, we have shown that primary afferent sensory neurons are necessary for disease activity in T cell-mediated immune hepatitis in mice. In the present…”
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Cephalostatin 1 selectively triggers the release of Smac/DIABLO and subsequent apoptosis that is characterized by an increased density of the mitochondrial matrix by DIRSCH, Verena M, MÜLLER, Irina M, EICHHORST, Sören T, PETTIT, George R, KAMANO, Yoshiaki, INOUE, Masuo, XU, Jun-Ping, ICHIHARA, Yoshitatsu, WANNER, Gerhard, VOLLMAR, Angelika M

“…Cephalostatin 1 is a bis-steroidal marine natural product with a unique cytotoxicity profile in the in vitro screen system of the National Cancer Institute,…”
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The soy isoflavone genistein induces a late but sustained activation of the endothelial nitric oxide‐synthase system in vitro by Räthel, Thomas R, Leikert, Jürgen F, Vollmar, Angelika M, Dirsch, Verena M

“…1 Cardiovascular diseases are known as the major causes of death or disability in western countries. Decreased bioavailability of endothelial derived nitric…”
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Inhibition of cyclooxygenase-2 by natriuretic peptides by Kiemer, Alexandra K, Lehner, Martin D, Hartung, Thomas, Vollmar, Angelika M

“…The atrial natriuretic peptide (ANP) has been suggested to possess immunomodulatory potential because of its property to alter macrophage functions via its…”
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Autocrine Regulation of Inducible Nitric-oxide Synthase in Macrophages by Atrial Natriuretic Peptide by Kiemer, Alexandra K., Vollmar, Angelika M.

“…Atrial natriuretic peptide (ANP), a cardiovascular hormone, has been shown to inhibit synthesis of nitric oxide in lipopolysaccharide (LPS)-activated mouse…”
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Reliable in vitro measurement of nitric oxide released from endothelial cells using low concentrations of the fluorescent probe 4,5-diaminofluorescein by Leikert, Jürgen F, Räthel, Thomas R, Müller, Christian, Vollmar, Angelika M, Dirsch, Verena M

“…4,5-Diaminofluorescein (DAF-2) and its membrane-permeable derivate DAF-2 diacetate are fluorescent probes that have been developed to perform real-time…”
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The atrial natriuretic peptide regulates the production of inflammatory mediators in macrophages by Kiemer, A K, Vollmar, A M

“…The atrial natriuretic peptide (ANP), a member of the natriuretic peptide family, is a cardiovascular hormone which possesses well defined natriuretic,…”
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