Search Results - "Vollenweider, Franz X."
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Psychometric evaluation of the altered states of consciousness rating scale (OAV)
Published in PloS one (31-08-2010)“…The OAV questionnaire has been developed to integrate research on altered states of consciousness (ASC). It measures three primary and one secondary dimensions…”
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Acute Effects of Lysergic Acid Diethylamide in Healthy Subjects
Published in Biological psychiatry (1969) (15-10-2015)“…Abstract Background After no research in humans for >40 years, there is renewed interest in using lysergic acid diethylamide (LSD) in clinical psychiatric…”
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Prediction of psilocybin response in healthy volunteers
Published in PloS one (17-02-2012)“…Responses to hallucinogenic drugs, such as psilocybin, are believed to be critically dependent on the user's personality, current mood state, drug…”
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Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor
Published in eLife (25-10-2018)“…Lysergic acid diethylamide (LSD) has agonist activity at various serotonin (5-HT) and dopamine receptors. Despite the therapeutic and scientific interest in…”
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Effects of serotonin 2A/1A receptor stimulation on social exclusion processing
Published in Proceedings of the National Academy of Sciences - PNAS (03-05-2016)“…Social ties are crucial for physical and mental health. However, psychiatric patients frequently encounter social rejection. Moreover, an increased reactivity…”
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Psilocybin exerts distinct effects on resting state networks associated with serotonin and dopamine in mice
Published in NeuroImage (Orlando, Fla.) (15-01-2021)“…Hallucinogenic agents have been proposed as potent antidepressants; this includes the serotonin (5-HT) receptor 2A agonist psilocybin. In human subjects,…”
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Psilocybin-Induced Deficits in Automatic and Controlled Inhibition are Attenuated by Ketanserin in Healthy Human Volunteers
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2012)“…The serotonin-2A receptor (5-HT(2A)R) has been implicated in the pathogenesis of schizophrenia and related inhibitory gating and behavioral inhibition deficits…”
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Modulation of Social Cognition via Hallucinogens and "Entactogens"
Published in Frontiers in psychiatry (03-12-2019)“…Social cognition is a fundamental ability in human everyday lives. Deficits in social functioning also represent a core aspect of many psychiatric disorders…”
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Psilocybin enhances insightfulness in meditation: a perspective on the global topology of brain imaging during meditation
Published in Scientific reports (26-03-2024)“…In this study, for the first time, we explored a dataset of functional magnetic resonance images collected during focused attention and open monitoring…”
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Author Correction: Psilocybin enhances insightfulness in meditation: a perspective on the global topology of brain imaging during meditation
Published in Scientific reports (23-04-2024)Get full text
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Psilocybin-induced changes in cerebral blood flow are associated with acute and baseline inter-individual differences
Published in Scientific reports (14-10-2023)“…Research into the use of psilocybin for the treatment of psychiatric disorders is a growing field. Nevertheless, robust brain–behavior relationships linking…”
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LSD Increases Primary Process Thinking via Serotonin 2A Receptor Activation
Published in Frontiers in pharmacology (08-11-2017)“…Stimulation of serotonin 2A (5-HT2A) receptors by lysergic acid diethylamide (LSD) and related compounds such as psilocybin has previously been shown to…”
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The mixed serotonin receptor agonist psilocybin reduces threat-induced modulation of amygdala connectivity
Published in NeuroImage clinical (01-01-2016)“…Stimulation of serotonergic neurotransmission by psilocybin has been shown to shift emotional biases away from negative towards positive stimuli. We have…”
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Transcriptomics-informed large-scale cortical model captures topography of pharmacological neuroimaging effects of LSD
Published in eLife (27-07-2021)“…Psychoactive drugs can transiently perturb brain physiology while preserving brain structure. The role of physiological state in shaping neural function can…”
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Psychedelic drugs: neurobiology and potential for treatment of psychiatric disorders
Published in Nature reviews. Neuroscience (01-11-2020)“…Renewed interest in the use of psychedelics in the treatment of psychiatric disorders warrants a better understanding of the neurobiological mechanisms…”
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In vitro and in vivo metabolism of psilocybin's active metabolite psilocin
Published in Frontiers in pharmacology (29-04-2024)“…, psilocybin is rapidly dephosphorylated to psilocin which induces psychedelic effects by interacting with the 5-HT receptor. Psilocin primarily undergoes…”
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The Effects of the Preferential 5-HT2A Agonist Psilocybin on Prepulse Inhibition of Startle in Healthy Human Volunteers Depend on Interstimulus Interval
Published in Neuropsychopharmacology (New York, N.Y.) (01-09-2007)“…Schizophrenia patients exhibit impairments in prepulse inhibition (PPI) of the startle response. Hallucinogenic 5-HT(2A) receptor agonists are used for animal…”
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Ketamine induces multiple individually distinct whole-brain functional connectivity signatures
Published in eLife (17-04-2024)“…Ketamine has emerged as one of the most promising therapies for treatment-resistant depression. However, inter-individual variability in response to ketamine…”
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Mapping brain-behavior space relationships along the psychosis spectrum
Published in eLife (20-07-2021)“…Difficulties in advancing effective patient-specific therapies for psychiatric disorders highlight a need to develop a stable neurobiologically grounded…”
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The neurobiology of psychedelic drugs: implications for the treatment of mood disorders
Published in Nature reviews. Neuroscience (01-09-2010)“…In this Perspective, Vollenweider and Kometer discuss the clinical potential of psychedelic drugs for the treatment of various psychiatric disorders, and…”
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