Search Results - "Volker Möbus"

Adjuvant Dose-Dense Chemotherapy in Breast Cancer: Standard of Care in High-Risk Patients by Möbus, Volker

“…Meta-analyses persistently confirm the superiority of dose-dense chemotherapy in comparison with standard chemotherapy. In contrast, individual studies have…”
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Glembatumumab vedotin for patients with metastatic, gpNMB overexpressing, triple-negative breast cancer (“METRIC”): a randomized multicenter study by Vahdat, Linda T., Schmid, Peter, Forero-Torres, Andres, Blackwell, Kimberly, Telli, Melinda L., Melisko, Michelle, Möbus, Volker, Cortes, Javier, Montero, Alberto J., Ma, Cynthia, Nanda, Rita, Wright, Gail S., He, Yi, Hawthorne, Thomas, Bagley, Rebecca G., Halim, Abdel-Baset, Turner, Christopher D., Yardley, Denise A.

“…The METRIC study (NCT#0199733) explored a novel antibody–drug conjugate, glembatumumab vedotin (GV), targeting gpNMB that is overexpressed in ~40% of patients…”
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Effect of Tailored Dose-Dense Chemotherapy vs Standard 3-Weekly Adjuvant Chemotherapy on Recurrence-Free Survival Among Women With High-Risk Early Breast Cancer: A Randomized Clinical Trial by Foukakis, Theodoros, von Minckwitz, Gunter, Bengtsson, Nils-Olof, Brandberg, Yvonne, Wallberg, Birgitta, Fornander, Tommy, Mlineritsch, Brigitte, Schmatloch, Sabine, Singer, Christian F, Steger, Günther, Egle, Daniel, Karlsson, Eva, Carlsson, Lena, Loibl, Sibylle, Untch, Michael, Hellström, Mats, Johansson, Hemming, Anderson, Harald, Malmström, Per, Gnant, Michael, Greil, Richard, Möbus, Volker, Bergh, Jonas

“…IMPORTANCE: Standard dosing of chemotherapy based on body surface area results in marked interpatient variation in pharmacokinetics, toxic effects, and…”
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German Adjuvant Intergroup Node-Positive Study: A Phase III Trial to Compare Oral Ibandronate Versus Observation in Patients With High-Risk Early Breast Cancer by von Minckwitz, Gunter, Möbus, Volker, Schneeweiss, Andreas, Huober, Jens, Thomssen, Christoph, Untch, Michael, Jackisch, Christian, Diel, Ingo J., Elling, Dirk, Conrad, Bettina, Kreienberg, Rolf, Müller, Volkmar, Lück, Hans-Joachim, Bauerfeind, Ingo, Clemens, Michael, Schmidt, Marcus, Noeding, Stefanie, Forstbauer, Helmut, Barinoff, Jana, Belau, Antje, Nekljudova, Valentina, Harbeck, Nadia, Loibl, Sibylle

“…Bisphosphonates prevent skeletal-related events in patients with metastatic breast cancer. Their effect in early breast cancer is controversial. Ibandronate is…”
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Efficacy of Endocrine Therapy for the Treatment of Breast Cancer in Men: Results from the MALE Phase 2 Randomized Clinical Trial by Reinisch, Mattea, Seiler, Sabine, Hauzenberger, Tanja, Kamischke, Axel, Schmatloch, Sabine, Strittmatter, Hans-Joachim, Zahm, Dirk-Michael, Thode, Christian, Furlanetto, Jenny, Strik, Dominika, Möbus, Volker, Reimer, Toralf, Sinn, Bruno Valentin, Stickeler, Elmar, Marmé, Frederik, Janni, Wolfgang, Schmidt, Marcus, Rudlowski, Christian, Untch, Michael, Nekljudova, Valentina, Loibl, Sibylle

“…The extent of changes in estradiol levels in male patients with hormone receptor-positive breast cancer receiving standard endocrine therapies is unknown. The…”
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Radiological Patterns of Brain Metastases in Breast Cancer Patients: A Subproject of the German Brain Metastases in Breast Cancer (BMBC) Registry by Laakmann, Elena, Witzel, Isabell, Scriba, Verena, Grzyska, Ulrich, Zu Eulenburg, Christine, Burchardi, Nicole, Hesse, Tobias, Würschmidt, Florian, Fehm, Tanja, Möbus, Volker, von Minckwitz, Gunter, Loibl, Sibylle, Park-Simon, Tjoung-Won, Mueller, Volkmar

“…Evidence about distribution patterns of brain metastases with regard to breast cancer subtypes and its influence on the prognosis of patients is insufficient…”
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Randomized Phase III Trial of Topotecan Following Carboplatin and Paclitaxel in First-line Treatment of Advanced Ovarian Cancer: A Gynecologic Cancer Intergroup Trial of the AGO-OVAR and GINECO by Pfisterer, Jacobus, Weber, Béatrice, Reuss, Alexander, Kimmig, Rainer, du Bois, Andreas, Wagner, Uwe, Bourgeois, Hugues, Meier, Werner, Costa, Serban, Blohmer, Jens-Uwe, Lortholary, Alain, Olbricht, Sigrid, Stähle, Anne, Jackisch, Christian, Hardy-Bessard, Anne-Claire, Möbus, Volker, Quaas, Jens, Richter, Barbara, Schröder, Willibald, Geay, Jean-François, Lück, Hans-Joachim, Kuhn, Walther, Meden, Harald, Nitz, Ulrike, Pujade-Lauraine, Eric

“…Background: The combination of carboplatin and paclitaxel is the standard of care for the treatment of ovarian cancer, yet rates of recurrence and death remain…”
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Subcutaneous injection of trastuzumab into the thigh versus abdominal wall in patients with HER2-positive early breast cancer: Pharmacokinetic, safety and patients' preference - Substudy of the randomised phase III GAIN-2 study by Reinisch, Mattea, Untch, Michael, Mahlberg, Rolf, Reimer, Toralf, Hitschold, Thomas, Marmé, Frederik, Aydogdu, Mustafa, Schmatloch, Sabine, Lück, Hans-Joachim, Schmidt, Marcus, Ladda, Ekkehart, Sinn, Bruno Valentin, Klare, Peter, Janni, Wolfgang, Jackisch, Christian, Denkert, Carsten, Seiler, Sabine, Göhler, Thomas, Michel, Laura, Burchardi, Nicole, Stickeler, Elmar, Rey, Julia, Klutinus, Nicole, Möbus, Volker, Loibl, Sibylle

“…Trastuzumab given intravenously in combination with chemotherapy is standard of care for patients with early HER2-positive breast cancer (BC). Different…”
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Intensive Dose-Dense Compared With Conventionally Scheduled Preoperative Chemotherapy for High-Risk Primary Breast Cancer by UNTCH, Michael, MÖBUS, Volker, KAHLERT, Stephen, VON KOCH, Franz, PETRY, Karl Ulrich, WALLWIENER, Diethelm, KREIENBERG, Rolf, ALBERT, Ute-Susann, LÜCK, Hans-Joachim, HINKE, Axel, JÄNICKE, Fritz, KONECNY, Gottfried E, KUHN, Walther, MUCK, Bernd Rudolph, THOMSSEN, Christoph, BAUERFEIND, Ingo, HARBECK, Nadia, WERNER, Christoph, LEBEAU, Annette, SCHNEEWEISS, Andreas

“…To compare preoperative intense dose-dense (IDD) chemotherapy with conventionally scheduled preoperative chemotherapy in high-risk primary breast cancer (BC)…”
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TGFB-induced factor homeobox 1 (TGIF) expression in breast cancer by Stürken, Christine, Möbus, Volker, Milde-Langosch, Karin, Schmatloch, Sabine, Fasching, Peter A, Rüschoff, Josef, Stickeler, Elmar, Henke, Rolf-Peter, Denkert, Carsten, Hanker, Lars, Schem, Christian, Vladimirova, Valentina, Karn, Thomas, Nekljudova, Valentina, Köhne, Claus-Henning, Marmé, Frederik, Schumacher, Udo, Loibl, Sibylle, Müller, Volkmar

“…Background Breast cancer (BC) is the most frequent female cancer and preferentially metastasizes to bone. The transcription factor TGFB-induced factor homeobox…”
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Characteristics and Clinical Outcome of Breast Cancer Patients with Asymptomatic Brain Metastases by Laakmann, Elena, Witzel, Isabell, Neunhöffer, Tanja, Weide, Rudolf, Schmidt, Marcus, Park-Simon, Tjoung-Won, Möbus, Volker, Mundhenke, Christoph, Polasik, Arkadius, Lübbe, Kristina, Hesse, Tobias, Riecke, Kerstin, Thill, Marc, Fasching, Peter A., Denkert, Carsten, Fehm, Tanja, Nekljudova, Valentina, Rey, Julia, Loibl, Sibylle, Müller, Volkmar

“…Background: Brain metastases (BM) have become a major challenge in patients with metastatic breast cancer. Methods: The aim of this analysis was to…”
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Correction to: TGFB-induced factor homeobox 1 (TGIF) expression in breast cancer by Stürken, Christine, Möbus, Volker, Milde-Langosch, Karin, Schmatloch, Sabine, Fasching, Peter A, Rüschoff, Josef, Stickeler, Elmar, Henke, Rolf-Peter, Denkert, Carsten, Hanker, Lars, Schem, Christian, Vladimirova, Valentina, Karn, Thomas, Nekljudova, Valentina, Köhne, Claus-Henning, Marmé, Frederik, Schumacher, Udo, Loibl, Sibylle, Müller, Volkmar

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Predicting Prognosis of Breast Cancer Patients with Brain Metastases in the BMBC Registry-Comparison of Three Different GPA Prognostic Scores by Riecke, Kerstin, Müller, Volkmar, Weide, Rudolf, Schmidt, Marcus, Park-Simon, Tjoung-Won, Möbus, Volker, Mundhenke, Christoph, Polasik, Arkadius, Lübbe, Kristina, Hesse, Tobias, Laakmann, Elena, Thill, Marc, A Fasching, Peter, Denkert, Carsten, Fehm, Tanja, Nekljudova, Valentina, Rey, Julia, Loibl, Sibylle, Witzel, Isabell

“…Several scores have been developed in order to estimate the prognosis of patients with brain metastases (BM) by objective criteria. The aim of this analysis…”
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The role of cervical cultures to guide perioperative antibiotics in cervical cerclage - a retrospective analysis of 65 consecutive cases by Moisidis-Tesch, Christina M., Ginsberg, Norman A., Uleer, Christoph, Möbus, Volker J.

“…Objective: The objective of this study is to examine results of bacterial cultures of the cervix prior to cerclage placement and how these may be used to guide…”
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13th St. Gallen International Breast Cancer Conference 2013: Primary Therapy of Early Breast Cancer Evidence, Controversies, Consensus - Opinion of a German Team of Experts (Zurich 2013) by Untch, Michael, Gerber, Bernd, Harbeck, Nadia, Jackisch, Christian, Marschner, Norbert, Möbus, Volker, von Minckwitz, Gunter, Loibl, Sibylle, Beckmann, Matthias W., Blohmer, Jens-Uwe, Costa, Serban-Dan, Decker, Thomas, Diel, Ingo, Dimpfl, Thomas, Eiermann, Wolfgang, Fehm, Tanja, Friese, Klaus, Jänicke, Fritz, Janni, Wolfgang, Jonat, Walter, Kiechle, Marion, Köhler, Uwe, Lück, Hans-Joachim, Maass, Nicolai, Possinger, Kurt, Rody, Achim, Scharl, Anton, Schneeweiss, Andreas, Thomssen, Christoph, Wallwiener, Diethelm, Welt, Anja

“…The International Consensus Conference on the treatment of primary breast cancer takes place every two years in St. Gallen, Switzerland. The panel in St…”
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GAIN2 trial overall survival with intense versus tailored dose dense chemotherapy in early breast cancer by Möbus, Volker, Lück, Hans-Joachim, Ladda, Ekkehart, Klare, Peter, Engels, Knut, Schmidt, Marcus, Schneeweiss, Andreas, Grischke, Eva-Maria, Wachsmann, Grischa, Forstbauer, Helmut, Untch, Michael, Marmé, Frederik, Blohmer, Jens-Uwe, Jackisch, Christian, Huober, Jens, Stickeler, Elmar, Reinisch, Mattea, Link, Theresa, Sinn, Bruno, Janni, Wolfgang, Denkert, Carsten, Seiler, Sabine, Solbach, Christine, Schmatloch, Sabine, Rey, Julia, Loibl, Sibylle

“…GAIN-2 trial evaluated the optimal intense dose-dense (idd) strategy for high-risk early breast cancer. This study reports the secondary endpoints pathological…”
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Phase III Trial of High-Dose Sequential Chemotherapy With Peripheral Blood Stem Cell Support Compared With Standard Dose Chemotherapy for First-Line Treatment of Advanced Ovarian Cancer: Intergroup Trial of the AGO-Ovar/AIO and EBMT by MÖBUS, Volker, WANDT, Hannes, FRICKHOFEN, Norbert, BENGALA, Carmelo, CHAMPION, Kim, KIMMIG, Rainer, OSTERMANN, Helmut, HINKE, Axel, LEDERMANN, Jonathan A

“…Although ovarian cancer is one of the most chemotherapy-sensitive solid tumors, cure after radical surgery and chemotherapy is uncommon. A randomized trial…”
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HER-2/neu Gene Amplification and Response to Paclitaxel in Patients With Metastatic Breast Cancer by Konecny, Gottfried E., Thomssen, Christoph, Lück, Hans Joachim, Untch, Michael, Wang, He-Jing, Kuhn, Walter, Eidtmann, Holger, Bois, Andreas du, Olbricht, Sigrid, Steinfeld, Dieter, Möbus, Volker, Minckwitz, Gunter von, Dandekar, Suganda, Ramos, Lillian, Pauletti, Giovanni, Pegram, Mark D., Jänicke, Fritz, Slamon, Dennis J.

“…Background: HER-2/neu overexpressionappears to be associated with improved response to anthracycline-based chemotherapy, but its association with response to…”
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Identification of L1CAM, Jagged2 and Neuromedin U as ovarian cancer-associated antigens by Euer, Nicole I, Kaul, Sepp, Deissler, Helmut, Möbus, Volker J, Zeillinger, Robert, Weidle, Ulrich H

“…In order to identify tumor-associated genes of ovarian carcinoma, we have investigated the transcriptional profile of 11 ovarian tumor cell lines and 2…”
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Immunological Consolidation of Ovarian Carcinoma Recurrences with Monoclonal Anti-Idiotype Antibody ACA125: Immune Responses and Survival in Palliative Treatment by Uwe Wagner, Siegmund Köhler, Silke Reinartz, Patrick Giffels, Jens Huober, Kirsten Renke, Harald Schlebusch, Hans-Jürgen Biersack, Volker Möbus, Rolf Kreienberg, Thomas Bauknecht, Dieter Krebs, Diethelm Wallwiener

“…The aim of the present study was to assess whether the induction of specific immune responses by vaccination with the murine monoclonal anti-idiotypic antibody…”
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