Search Results - "Volk, H D"

Activity and components of the granulocyte colony‐stimulating factor pathway in hidradenitis suppurativa by Wolk, K., Brembach, T.‐C., Šimaitė, D., Bartnik, E., Cucinotta, S., Pokrywka, A., Irmer, M.L., Triebus, J., Witte‐Händel, E., Salinas, G., Leeuw, T., Volk, H.‐D., Ghoreschi, K., Sabat, R.

“…Summary Background Hidradenitis suppurativa (HS) is a chronic inflammatory disease, characterized by painful, purulent and destructive skin alterations in…”
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TCR Repertoire Analysis by Next Generation Sequencing Allows Complex Differential Diagnosis of T Cell–Related Pathology by Dziubianau, M., Hecht, J., Kuchenbecker, L., Sattler, A., Stervbo, U., Rödelsperger, C., Nickel, P., Neumann, A. U., Robinson, P. N., Mundlos, S., Volk, H.‐D., Thiel, A., Reinke, P., Babel, N.

“…Clonotype analysis is essential for complete characterization of antigen‐specific T cells. Moreover, knowledge on clonal identity allows tracking of…”
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Mesenchymal Stromal Cells Prevent Allostimulation In Vivo and Control Checkpoints of Th1 Priming: Migration of Human DC to Lymph Nodes and NK Cell Activation by Consentius, C., Akyüz, L., Schmidt‐Lucke, J. A., Tschöpe, C., Pinzur, L., Ofir, R., Reinke, P., Volk, H.‐D., Juelke, K.

“…Although the immunomodulatory potency of mesenchymal stromal cells (MSC) is well established, the mechanisms behind are still not clear. The crosstalk between…”
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Novel GMP‐Compatible Protocol Employing an Allogeneic B Cell Bank for Clonal Expansion of Allospecific Natural Regulatory T Cells by Landwehr‐Kenzel, S., Issa, F., Luu, S.‐H., Schmück, M., Lei, H., Zobel, A., Thiel, A., Babel, N., Wood, K., Volk, H.‐D., Reinke, P.

“…The adoptive transfer of natural regulatory T cells (nTreg) is a new option to reshape undesired immune reactivity in autoimmunity and transplantation toward…”
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Interleukin-10 therapy--review of a new approach by Asadullah, K, Sterry, W, Volk, H D

“…Interleukin (IL)-10 is an important immunoregulatory cytokine produced by many cell populations. Its main biological function seems to be the limitation and…”
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Lipocalin‐2 is expressed by activated granulocytes and keratinocytes in affected skin and reflects disease activity in acne inversa/hidradenitis suppurativa by Wolk, K., Wenzel, J., Tsaousi, A., Witte‐Händel, E., Babel, N., Zelenak, C., Volk, H.‐D., Sterry, W., Schneider‐Burrus, S., Sabat, R.

“…Summary Background Acne inversa (AI)/hidradenitis suppurativa is a chronic inflammatory disease characterized by painful axillary, inguinal and perianal skin…”
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Induction of Allograft Tolerance by Monoclonal CD3 Antibodies: A Matter of Timing by You, S., Zuber, J., Kuhn, C., Baas, M., Valette, F., Sauvaget, V., Sarnacki, S., Sawitzki, B., Bach, J.‐F., Volk, H.‐D., Chatenoud, L.

“…Despite remarkable progress in organ transplantation through the development of a wealth of immunosuppressive drugs highly effective at controlling acute…”
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Despite IFN-λ receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines by Witte, K, Gruetz, G, Volk, H-D, Looman, A C, Asadullah, K, Sterry, W, Sabat, R, Wolk, K

“…Interferon (IFN)-λ1, -2 and -3 (also designated as interleukin (IL)-29, IL-28α and IL-28β) represent a new subfamily within the class II cytokine family. They…”
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Stroke-induced immunodepression and post-stroke infections: Lessons from the preventive antibacterial therapy in stroke trial by Klehmet, J, Harms, H, Richter, M, Prass, K, Volk, H.D, Dirnagl, U, Meisel, A, Meisel, C

“…Abstract Infections are a leading cause of death in patients with acute CNS injury such as stroke. Recent experimental evidence indicated that stroke leads to…”
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Early post-transplant urinary IP-10 expression after kidney transplantation is predictive of short- and long-term graft function by Matz, M., Beyer, J., Wunsch, D., Mashreghi, M.-F., Seiler, M., Pratschke, J., Babel, N., Volk, H.-D., Reinke, P., Kotsch, K.

“…The early identification of renal transplant recipients at enhanced risk of developing acute and subclinical rejection would allow individualized adjustment of…”
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Clinical Development of Cell Therapies: Setting the Stage for Academic Success by Abou‐El‐Enein, M, Volk, H‐D, Reinke, P

“…Cellular therapies have potential to treat a wide range of diseases with autologous immunotherapies showing unprecedented therapeutic promise in clinical…”
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Brain Death Activates Donor Organs and Is Associated with a Worse I/R Injury After Liver Transplantation by Weiss, S., Kotsch, K., Francuski, M., Reutzel‐Selke, A., Mantouvalou, L, Klemz, R., Kuecuek, O., Jonas, S., Wesslau, C., Ulrich, F., Pascher, A., Volk, H‐D., Tullius, S. G., Neuhaus, P., Pratschke, J.

“…The majority of transplants are derived from donors who suffered from brain injury. There is evidence that brain death causes inflammatory changes in the…”
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Therapeutic immunomodulation using a virus—the potential of inactivated orf virus by Weber, O., Mercer, A. A., Friebe, A., Knolle, P., Volk, H.-D.

“…Viruses can manipulate the immune response against them by various strategies to influence immune cells, i.e. by over-activation leading to functional…”
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Molecular Analysis of Renal Allograft Biopsies—More Than a Nice Toy for Researchers? by Volk, H.‐D., Sawitzki, B., Reinke, P.

“…This editorial discuss two papers (see pages 634 and 645) on molecular diagnosis of kidney transplant injury as an alternative to standard histopathological…”
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Permanent CNI Treatment for Prevention of Renal Allograft Rejection in Sensitized Hosts Can Be Replaced by Regulatory T Cells by Siepert, A., Ahrlich, S., Vogt, K., Appelt, C., Stanko, K., Kühl, A., van den Brandt, J., Reichardt, H. M., Nizze, H., Lehmann, M., Tiedge, M., Volk, H.‐D., Sawitzki, B., Reinke, P.

“…Recent data suggest that donor‐specific memory T cells (Tmem) are an independent risk factor for rejection and poor graft function in patients and a major…”
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Identification of Gene Markers for the Prediction of Allograft Rejection or Permanent Acceptance by Sawitzki, B., Bushell, A., Steger, U., Jones, N., Risch, K., Siepert, A., Lehmann, M., Schmitt‐Knosalla, I., Vogt, K., Gebuhr, I., Wood, K., Volk, H.‐D.

“…The clinical success of new treatment strategies aiming on inducing permanent graft acceptance will rely on the ability to determine whether specific…”
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Adoptive T‐Cell Therapy of a Lung Transplanted Patient with Severe CMV Disease and Resistance to Antiviral Therapy by Brestrich, G., Zwinger, S., Fischer, A., Schmück, M., Röhmhild, A., Hammer, M. H., Kurtz, A., Uharek, L., Knosalla, C., Lehmkuhl, H., Volk, H.‐D., Reinke, P.

“…Infections with cytomegalovirus (CMV) can induce severe complications after transplantation, particularly in patients resistant to virostatic therapy. Adoptive…”
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Human CD45RA(-) FoxP3(hi) Memory-Type Regulatory T Cells Show Distinct TCR Repertoires With Conventional T Cells and Play an Important Role in Controlling Early Immune Activation by Lei, H, Kuchenbecker, L, Streitz, M, Sawitzki, B, Vogt, K, Landwehr-Kenzel, S, Millward, J, Juelke, K, Babel, N, Neumann, A, Reinke, P, Volk, H-D

“…Adoptive immunotherapy with regulatory T cells (Treg) is a new option to promote immune tolerance following solid organ transplantation (SOT). However, Treg…”
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The effect of induction therapy on established CMV specific T cell immunity in living donor kidney transplantation by Stranavova, L, Hruba, P, Girmanova, E, Tycova, I, Slavcev, A, Fronek, J, Slatinska, J, Reinke, P, Volk, H-D, Viklicky, O

“…Cytomegalovirus (CMV) infection influences both short and long term outcomes in immunosuppressed organ transplant recipients. The aim of this study was to…”
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Cytomegalovirus‐Specific Regulatory and Effector T Cells Share TCR Clonality—Possible Relation to Repetitive CMV Infections by Schwele, S., Fischer, A. M., Brestrich, G., Wlodarski, M. W., Wagner, L., Schmueck, M., Roemhild, A., Thomas, S., Hammer, M. H., Babel, N., Kurtz, A., Maciejewski, J. P., Reinke, P., Volk, H.‐D.

“…Cytomegalovirus (CMV) infections have a major impact on morbidity and mortality of transplant patients. Among the complex antiviral T‐cell response, CMV‐IE‐1…”
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