Search Results - "Vokurka, M"

Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis by Vokurka, M, Krijt, J, Sulc, K, Necas, E

“…Hepcidin, a key regulator of iron metabolism, decreases intestinal absorption of iron and its release from macrophages. Iron, anemia, hypoxia, and inflammation…”
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Proteomic approach for identification of IgA nephropathy-related biomarkers in urine by Prikryl, P, Vojtova, L, Maixnerova, D, Vokurka, M, Neprasova, M, Zima, T, Tesar, V

“…Proteinuria is often used as a surrogate marker in monitoring and predicting outcome in patients with chronic kidney diseases, but it is non-specific. IgAN…”
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Anti-CD38 Therapy with Daratumumab for Relapsed/Refractory CD20-Negative Diffuse Large B-Cell Lymphoma by Vockova, P, Svaton, M, Karolova, J, Pokorna, E, Vokurka, M, Klener, P

“…Diffuse large B-cell lymphoma (DLBCL) is the most common and one of the most aggressive subtypes of non-Hodgkin's lymphomas. Front-line therapy consists of…”
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Serum hepcidin is increased in ANCA-associated vasculitis and correlates with activity markers by Přikryl, P, Hrušková, Z, Konopásek, P, Hladinová, Z, Tesař, V, Vokurka, M

“…Hepcidin is a key regulator of iron metabolism and plays an important role in many pathologies. It is increased by iron administration and by inflammation,…”
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Decreased hemojuvelin protein levels in mask mice lacking matriptase-2-dependent proteolytic activity by Frýdlová, J, Fujikura, Y, Vokurka, M, Nečas, E, Krijt, J

“…Matriptase-2, a membrane protein encoded by the Tmprss6 gene, is a negative regulator of hepcidin expression. Although matriptase-2 has been proposed to cleave…”
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Plasma hepcidin correlates positively with interleukin-6 in patients undergoing pulmonary endarterectomy by Maruna, P, Vokurka, M, Lindner, J

“…Hepcidin, a recently discovered antimicrobial peptide synthesized in the liver, was identified to be the key mediator of iron metabolism and distribution…”
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Iron Overload Causes Alterations of E-Cadherin in the Liver by Fujikura, Y, Krijt, J, Povýšil, C, Mělková, Z, Přikryl, P, Vokurka, M, Nečas, E

“…Iron overload causes tissue damage in the liver, but its initial effects at the molecular and cellular level are not well understood. Epithelial cadherin…”
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Hepcidin expression in adipose tissue increases during cardiac surgery by Vokurka, M, Lacinová, Z, Kremen, J, Kopecký, P, Bláha, J, Pelinková, K, Haluzík, M, Necas, E

“…Hepcidin, a key regulator of iron metabolism, plays a crucial role in the pathogenesis of anemia of chronic disease. Although it is produced mainly in the…”
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Hepcidin downregulation by repeated bleeding is not mediated by soluble hemojuvelin by Krijt, J, Fujikura, Y, Sefc, L, Vokurka, M, Hlobenová, T, Necas, E

“…Hepcidin is a key regulator of iron homeostasis, while hemojuvelin is an important component of the hepcidin regulation pathway. It has been recently proposed…”
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Hepcidin expression in the liver of mice with implanted tumour reacts to iron deficiency, inflammation and erythropoietin administration by Vokurka, M, Krijt, J, Vávrová, J, Nečas, E

“…Cancer is known to be an important cause of anaemia due to several factors including iron deficiency and inflammation. Hepcidin, a key regulator of iron…”
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Sequence capture-PCR improves detection of mycobacterial DNA in clinical specimens by MANGIAPAN, G, VOKURKA, M, SCHOULS, L, CADRANEL, J, LECOSSIER, D, VAN EMBDEN, J, HANCE, A. J

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Effect of lipopolysaccharide and bleeding on the expression of intestinal proteins involved in iron and haem transport by Krijt, J, Vokurka, M, Sefc, L, Duricová, D, Necas, E

“…Haem carrier protein 1 (Hcpl) is a component of the haem-iron uptake pathway in the small intestine. Using quantitative real-time PCR, we examined the…”
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Application of omics approaches to study urinary biomarkers in ANCA - Associated vasculitides by Vojtova, L., Prikryl, P., Frydlova, J., Hruskova, Z., Vokurka, M., Zima, T., Tesar, V.

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Effect of the protoporphyrinogen oxidase-inhibiting herbicide fomesafen on liver uroporphyrin and heptacarboxylic porphyrin in two mouse strains by Krijt, J, Vokurka, M, Sanitrak, J, Janousek, V, van Holsteijn, I, Blaauboer, B J

“…The effect of the protoporphyrinogen oxidase-inhibiting herbicide fomesafen on liver porphyrin accumulation was studied in long-term high-dose experiments…”
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Expression of Rgmc, the murine ortholog of hemojuvelin gene, is modulated by development and inflammation, but not by iron status or erythropoietin by Krijt, Jan, Vokurka, Martin, Chang, Ko-Tung, Nečas, Emanuel

“…Mutations of hepcidin (HAMP) and hemo-juvelin (HJV) genes have been recently demonstrated to result in juvenile hemochromatosis. Expression of HAMP is…”
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Liver high performance liquid chromatographic porphyrin profiles in experimental porphyria induced by peroxidizing herbicides by Krijt, J, Sanitrák, J, Vokurka, M, Janousek, V

“…The effect of peroxidizing herbicides on the liver porphyrin content of experimental animals was examined. Mice treated with the herbicide oxadiazon…”
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Secretory response to light in rat Harderian gland: possible photoprotective role of Harderian porphyrin by Hugo, J, Krijt, J, Vokurka, M, Janousek, V

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Different expression pattern of hepcidin genes in the liver and pancreas of C57BL/6N and DBA/2N mice by Krijt, Jan, Čmejla, Radek, Sýkora, Viktor, Vokurka, Martin, Vyoral, Daniel, Nečas, Emanuel

“…Male C57BL/6 and DBA/2 mice differ in their liver iron content. The aim of this study was to examine possible differences in the expression of hepcidin genes (…”
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Vaccinia virus induces apoptosis of infected macrophages by Humlova, Zuzana, Vokurka, Martin, Esteban, Mariano, Melkova, Zora

“…Department of Pathological Physiology, Charles University, 1 st Medical Faculty, U nemocnice 5, 128 53, Prague 2, Czech Republic Centro Nacional de…”
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Hepcidin--a peptide regulating the quantity and distribution of iron in the body in healthy and disease states by Vokurka, M, Necas, E

“…Iron is an essential element and its amount and balance must be precisely regulated. Iron intestinal absorption is essential for the iron balance; however, the…”
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