Search Results - "Voituron, Nicolas"
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1
The role of serotonin in respiratory function and dysfunction
Published in Microbes and infection (30-11-2010)“…Abstract Serotonin (5-HT) is a neuromodulator–transmitter influencing global brain function. Past and present findings illustrate a prominent role for 5-HT in…”
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2
Cytoprotective effects of erythropoietin: What about the lung?
Published in Biomedicine & pharmacotherapy (01-07-2021)“…Erythropoietin (Epo) is a pleiotropic cytokine, essential for erythropoiesis. Epo and its receptor (Epo-R) are produced by several tissues and it is now…”
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3
Chronic pulmonary fibrosis alters the functioning of the respiratory neural network
Published in Frontiers in physiology (13-06-2023)“…Some patients with idiopathic pulmonary fibrosis present impaired ventilatory variables characterised by low forced vital capacity values associated with an…”
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4
Necdin shapes serotonergic development and SERT activity modulating breathing in a mouse model for Prader-Willi syndrome
Published in eLife (31-10-2017)“…Prader-Willi syndrome (PWS) is a genetic neurodevelopmental disorder that presents with hypotonia and respiratory distress in neonates. The -deficient mouse is…”
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In Transgenic Erythropoietin Deficient Mice, an Increase in Respiratory Response to Hypercapnia Parallels Abnormal Distribution of CO2/H+-Activated Cells in the Medulla Oblongata
Published in Frontiers in physiology (19-04-2022)“…Erythropoietin (Epo) and its receptor are expressed in central respiratory areas. We hypothesized that chronic Epo deficiency alters functioning of central…”
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The H3K27 Demethylase JMJD3 Is Required for Maintenance of the Embryonic Respiratory Neuronal Network, Neonatal Breathing, and Survival
Published in Cell reports (Cambridge) (29-11-2012)“…JMJD3 (KDM6B) antagonizes Polycomb silencing by demethylating lysine 27 on histone H3. The interplay of methyltransferases and demethylases at this residue is…”
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Exercising in Hypoxia and Other Stimuli: Heart Rate Variability and Ventilatory Oscillations
Published in Life (28-06-2021)“…Periodic breathing is a respiratory phenomenon frequently observed in patients with heart failure and in normal subjects sleeping at high altitude. However,…”
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A New Model of Acute Exacerbation of Experimental Pulmonary Fibrosis in Mice
Published in Cells (Basel, Switzerland) (26-10-2022)“…idiopathic pulmonary fibrosis (IPF) is the most severe form of fibrosing interstitial lung disease, characterized by progressive respiratory failure leading to…”
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The c-FOS Protein Immunohistological Detection: A Useful Tool As a Marker of Central Pathways Involved in Specific Physiological Responses In Vivo and Ex Vivo
Published in Journal of visualized experiments (25-04-2016)“…Many studies seek to identify and map the brain regions involved in specific physiological regulations. The proto-oncogene c-fos, an immediate early gene, is…”
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Dexmedetomidine and clonidine induce long-lasting activation of the respiratory rhythm generator of neonatal mice: Possible implication for critical care
Published in Respiratory physiology & neurobiology (15-01-2012)“…Highlights ► Dexmedetomidine and clonidine are commonly used alpha-2 adrenoceptor agonists. ► Whether they depress breathing in the critical care setting is…”
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Early breathing defects after moderate hypoxia or hypercapnia in a mouse model of Rett syndrome
Published in Respiratory physiology & neurobiology (31-08-2009)“…Abstract Rett syndrome (RTT) is a rare neurodevelopmental disease caused by mutations in the transcriptional repressor methyl-CpG-binding protein 2 (MeCP2) and…”
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12
Ventilatory and Autonomic Regulation in Sleep Apnea Syndrome: A Potential Protective Role for Erythropoietin?
Published in Frontiers in physiology (16-10-2018)“…Obstructive sleep apnea (OSA) is the most common form of sleep disordered breathing and is associated with wide array of cardiovascular morbidities. It has…”
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Effect of Gender on Chronic Intermittent Hypoxic Fosb Expression in Cardiorespiratory-Related Brain Structures in Mice
Published in Frontiers in physiology (25-06-2018)“…We aimed to delineate sex-based differences in neuroplasticity that may be associated with previously reported sex-based differences in physiological…”
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14
Sleep Apnea in Idiopathic Pulmonary Fibrosis: A Molecular Investigation in an Experimental Model of Fibrosis and Intermittent Hypoxia
Published in Life (Basel, Switzerland) (15-09-2021)“…Background: High prevalence of obstructive sleep apnea (OSA) is reported in incident and prevalent forms of idiopathic pulmonary fibrosis (IPF). We previously…”
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Key Brainstem Structures Activated during Hypoxic Exposure in One-day-old Mice Highlight Characteristics for Modeling Breathing Network in Premature Infants
Published in Frontiers in physiology (09-12-2016)“…We mapped and characterized changes in the activity of brainstem cell groups under hypoxia in one-day-old newborn mice, an animal model in which the central…”
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16
Effect of exercise training in rats exposed to chronic hypoxia: Application for Monge’s disease
Published in Physiological reports (01-04-2021)“…Physical exercise may improve hematological conditions in high altitude dwellers suffering from Chronic Mountain Sickness (CMS), in reducing hemoglobin…”
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Isoflurane anesthesia precipitates tauopathy and upper airways dysfunction in pre-symptomatic Tau.P301L mice: Possible implication for neurodegenerative diseases
Published in Neurobiology of disease (01-04-2012)“…Abstract The postoperative cognitive decline resulting from volatile anesthesia is gaining acceptance as a major health problem. The common anesthetic…”
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Raphé tauopathy alters serotonin metabolism and breathing activity in terminal Tau.P301L mice: Possible implications for tauopathies and Alzheimer's disease
Published in Respiratory physiology & neurobiology (15-09-2011)“…Abstract Tauopathies, including Alzheimer's disease are the most frequent neurodegenerative disorders in elderly people. Patients develop cognitive and…”
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Fluoxetine treatment abolishes the in vitro respiratory response to acidosis in neonatal mice
Published in PloS one (26-10-2010)“…To secure pH homeostasis, the central respiratory network must permanently adapt its rhythmic motor drive to environment and behaviour. In neonates, it is…”
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HIF and ER stress are involved in TGFβ1-mediated wound closure of alveolar epithelial cells
Published in Experimental lung research (2023)“…Purpose: Alveolar epithelium dysfunction is associated with a very large spectrum of disease and an abnormal repair capacity of the airway epithelium has been…”
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