Search Results - "Voisin, Grégory"
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The MHC class I peptide repertoire is molded by the transcriptome
Published in The Journal of experimental medicine (17-03-2008)“…Under steady-state conditions, major histocompatibility complex (MHC) I molecules are associated with self-peptides that are collectively referred to as the…”
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Gestational diabetes mellitus epigenetically affects genes predominantly involved in metabolic diseases
Published in Epigenetics (01-09-2013)“…Offspring exposed to gestational diabetes mellitus (GDM) have an increased risk for chronic diseases, and one promising mechanism for fetal metabolic…”
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The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation
Published in Molecular systems biology (27-09-2011)“…Self/non‐self discrimination is a fundamental requirement of life. Endogenous peptides presented by major histocompatibility complex class I (MHC I) molecules…”
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Oxidative stress modulates the expression of genes involved in cell survival in ΔF508 cystic fibrosis airway epithelial cells
Published in Physiological genomics (01-09-2014)“…Although cystic fibrosis (CF) pathophysiology is explained by a defect in CF transmembrane conductance regulator (CFTR) protein, the broad spectrum of disease…”
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The MHC I Immunopeptidome Is Moulded by the Transcriptome and Conceals a Tissue-Specific Signature
Published in Blood (16-11-2007)“…Background: Cell surface MHC I molecules are associated with self peptides that are collectively referred to as the self MHC I immunopeptidome (sMII). The sMII…”
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DNA Methylation Regulates RGS2-induced S100A12 Expression in Airway Epithelial Cells
Published in American journal of respiratory cell and molecular biology (01-11-2018)“…RGS2 is a key modulator of stress in human airway epithelial cells, especially of hyperresponsiveness and mucin hypersecretion, both of which are features of…”
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Recombinant human IL-15 trans-presentation by B leukemic cells from chronic lymphocytic leukemia induces autologous NK cell proliferation leading to improved anti-CD20 immunotherapy
Published in The Journal of immunology (1950) (01-10-2013)“…Recombinant human IL-15 (rhIL-15) is one of the most promising cytokines for antitumor immunotherapy. In physiology IL-15 trans-presentation by accessory cells…”
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Hepatocyte‐specific Ptpn6 deletion promotes hepatic lipid accretion, but reduces NAFLD in diet‐induced obesity: Potential role of PPARγ
Published in Hepatology (Baltimore, Md.) (01-05-2014)“…Hepatocyte‐specific Shp1 knockout mice (Ptpn6H‐KO) are protected from hepatic insulin resistance evoked by high‐fat diet (HFD) feeding for 8 weeks…”
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Epigenome-wide analysis in familial hypercholesterolemia identified new loci associated with high-density lipoprotein cholesterol concentration
Published in Epigenomics (01-12-2012)“…This study aims to assess whether epigenetic changes may account for high-density lipoprotein cholesterol (HDL-C) level variability in familial…”
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funtooNorm: an R package for normalization of DNA methylation data when there are multiple cell or tissue types
Published in Bioinformatics (15-02-2016)“…DNA methylation patterns are well known to vary substantially across cell types or tissues. Hence, existing normalization methods may not be optimal if they do…”
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Hepatocyte-specific Ptpn6 deletion promotes hepatic lipid accretion, but reduces NAFLD in diet-induced obesity: Potential role of PPAR[gamma]
Published in Hepatology (Baltimore, Md.) (01-05-2014)“…Hepatocyte-specific Shp1 knockout mice (Ptpn6H-KO) are protected from hepatic insulin resistance evoked by high-fat diet (HFD) feeding for 8 weeks…”
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Stimulation of MC38 tumor growth by insulin analog X10 involves the serine synthesis pathway
Published in Endocrine-related cancer (01-08-2012)“…Recent evidence suggests that type II diabetes is associated with increased risk and/or aggressive behavior of several cancers, including those arising from…”
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The alveolar type I cells: the new knight of the alveolus?
Published in The Journal of physiology (01-05-2006)Get full text
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