Search Results - "Voinea, Silviu Cristian"
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G Protein-Coupled Receptors (GPCRs)-Mediated Calcium Signaling in Ovarian Cancer: Focus on GPCRs activated by Neurotransmitters and Inflammation-Associated Molecules
Published in International journal of molecular sciences (07-11-2019)“…G-coupled protein receptors (GCPR) involve several signaling pathways, some of them being coupled with intracellular calcium (Ca ) mobilization. GPCRs were…”
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Endometriosis Associated Infertility: A Critical Review and Analysis on Etiopathogenesis and Therapeutic Approaches
Published in Medicina (Kaunas, Lithuania) (09-09-2020)“…Endometriosis represents a frequently diagnosed gynecological affliction in the reproductive timespan of women, defined by symptoms ranging from pelvic pain to…”
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Role of microRNAs as Clinical Cancer Biomarkers for Ovarian Cancer: A Short Overview
Published in Cells (Basel, Switzerland) (09-01-2020)“…Ovarian cancer has the highest mortality rate among gynecological cancers. Early clinical signs are missing and there is an urgent need to establish early…”
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miRNAs as Biomarkers in Disease: Latest Findings Regarding Their Role in Diagnosis and Prognosis
Published in Cells (Basel, Switzerland) (23-01-2020)“…MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of regulating mRNA through its degradation and adjusting protein levels. In…”
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The Roles of MicroRNAs in Male Infertility
Published in International journal of molecular sciences (13-03-2021)“…MicroRNAs applications were vastly studied throughout the years, spanning from potential cancer biomarkers to targeted therapies for various diseases. Out of…”
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Pregnancy-Related Extracellular Vesicles Revisited
Published in International journal of molecular sciences (09-04-2021)“…Extracellular vesicles (EVs) are small vesicles ranging from 20-200 nm to 10 μm in diameter that are discharged and taken in by many different types of cells…”
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MicroRNA Involvement in Signaling Pathways During Viral Infection
Published in Frontiers in cell and developmental biology (10-03-2020)“…The study of miRNAs started in 1993, when Lee et al. observed their involvement in the downregulation of a crucial protein known as LIN-14 in the nematode…”
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Unraveling Immunological Dynamics: HPV Infection in Women-Insights from Pregnancy
Published in Viruses (27-09-2023)“…During pregnancy, hormonal and immune adaptations are vital for supporting the genetically distinct fetus during elevated infection risks. The global…”
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Socio-economic disparities in prenatal prognosis and intervention accessibility
Published in Journal of Mind and Medical Sciences (31-10-2024)“…Objectives. This study aimed to assess the impact of socio-economic factors on prenatal care accessibility and outcomes and to evaluate the effectiveness of…”
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Gut Microbiome, Functional Food, Atherosclerosis, and Vascular Calcifications—Is There a Missing Link?
Published in Microorganisms (Basel) (09-09-2021)“…The gut microbiome is represented by the genome of all microorganisms (symbiotic, potential pathogens, or pathogens) residing in the intestine. These…”
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A Catastrophic Biodiversity Loss in the Environment Is Being Replicated on the Skin Microbiome: Is This a Major Contributor to the Chronic Disease Epidemic?
Published in Microorganisms (Basel) (01-11-2023)“…There has been a catastrophic loss of biodiversity in ecosystems across the world. A similar crisis has been observed in the human gut microbiome, which has…”
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Lynch Syndrome-associated Genomic Variants
Published in Journal of gastrointestinal and liver diseases : JGLD (29-09-2024)“…Lynch Syndrome, a hereditary disorder characterized by germline mutations in mismatch repair (MMR) genes, is a major contributor to colorectal cancers. It has…”
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Management of Breast Cancer Locoregional Recurrence
Published in Chirurgia (Bucharest, Romania : 1990) (01-07-2017)“…Breast cancer recurrence represents a challenge for clinicians because the management is not standardized and usually requires a multidisciplinary approach…”
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Somatic and germline mutations in endometrial cancer
Published in Journal of medicine and life (01-06-2024)“…Endometrial cancer is a complex disease influenced by both somatic and germline mutations. While individual mutations in genes such as , and members of the DNA…”
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Why Is Surgery Still Done after Concurrent Chemoradiotherapy in Locally Advanced Cervical Cancer in Romania?
Published in Cancers (01-01-2024)“…The incidence and mortality of cervical cancer are high in Romania compared to other European countries, particularly for locally advanced cervical cancer…”
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A Better Understanding of Axillary Lymph Node Dissection in the Era of Sentinel Lymph Node Biopsy
Published in Chirurgia (Bucharest, Romania : 1990) (01-03-2021)“…Axillary lymph node dissection (ALND) was and still is an important part of breast cancer treatment despite the fact the sentinel lymph node biopsy (SLNB) has…”
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Pathological Examination of the Late Embryonic Heart Using the Same 4-chamber and 3-vessel Planes Used in Fetal Echocardiography
Published in In vivo (Athens) (01-01-2021)“…The incidence of early pregnancy loss widely varies according to age, being considerably higher in older women. Severe congenital malformations play an…”
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Altered Organelle Calcium Transport in Ovarian Physiology and Cancer
Published in Cancers (10-08-2020)“…Calcium levels have a huge impact on the physiology of the female reproductive system, in particular, of the ovaries. Cytosolic calcium levels are influenced…”
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Correlation Studies between S100 Protein Level and Soluble MIA or Tissue MelanA and gp100 (HMB45) Expression in Cutaneous Melanoma
Published in Journal of personalized medicine (26-05-2023)“…(1) Background: Cutaneous melanoma (CM) originates from melanocytes and causes 90% of skin cancer deaths; therefore, the comparison of different soluble and…”
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Analysis of TP53 gene and particular infrastructural alterations in invasive ductal mammary carcinoma
Published in Romanian journal of morphology and embryology (01-04-2020)“…This study was conducted in order to determine the mutational status of TP53 gene and to determine some particular aspects from ultrastructural level in…”
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