Search Results - "Voigt, Mark M"

The Metalloproteinase adam19b Is Required for Sensory Axon Guidance in the Hindbrain by Cox, Jane A, Voigt, Mark M

“…Little is known about the molecular and cellular mechanisms involved in the formation of the cranial peripheral sensory system in vertebrates. To identify…”
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Peripheral glia have a pivotal role in the initial response to axon degeneration of peripheral sensory neurons in zebrafish by Pope, Holly M, Voigt, Mark M

“…Axon degeneration is a feature of many peripheral neuropathies. Understanding the organismal response to this degeneration may aid in identifying new…”
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Transcriptome Analysis of Chemically-Induced Sensory Neuron Ablation in Zebrafish by Cox, Jane A, Zhang, Bo, Pope, Holly M, Voigt, Mark M

“…Peripheral glia are known to have a critical role in the initial response to axon damage and degeneration. However, little is known about the cellular…”
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Molecular characterization and embryonic expression of the family of N‐methyl‐D‐aspartate receptor subunit genes in the zebrafish by Cox, Jane A., Kucenas, Sarah, Voigt, Mark M.

“…We present the cloning of 10 N‐methyl‐D‐aspartate (NMDA) receptor subunits from the zebrafish. These subunits fall into five subtypes, each containing two…”
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Topological analysis of the ATP‐gated ionotrophic P2X2 receptor subunit by Torres, Gonzalo E, Egan, Terrance M, Voigt, Mark M

“…We investigated the transmembrane topology of the P2X2 receptor subunit expressed in HEK 293 cells. Initial studies using two P2X subunits expressed in tandem…”
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Cloning and characterization of two novel zebrafish P2X receptor subunits by Diaz-Hernandez, Miguel, Cox, Jane A, Migita, Keisuke, Haines, William, Egan, Terrance M, Voigt, Mark M

“…In this report we describe the cloning and characterization of two P2X receptor subunits cloned from the zebrafish ( Danio rerio). Primary sequence analysis…”
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Diverse mechanisms for assembly of branchiomeric nerves by Cox, Jane A., LaMora, Angela, Johnson, Stephen L., Voigt, Mark M.

“…The formation of branchiomeric nerves (cranial nerves V, VII, IX and X) from their sensory, motor and glial components is poorly understood. The current model…”
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Novel role for carbamoyl phosphate synthetase 2 in cranial sensory circuit formation by Cox, Jane A., LaMora, Angela, Johnson, Stephen L., Voigt, Mark M.

“…•Sensory axon terminations in the hindbrain are disrupted in a cad null mutant.•Tunicamycin mimics the cad null phenotype.•Protein glycosylation is critical…”
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Use-Dependent Inhibition of P2X3 Receptors by Nanomolar Agonist by Pratt, Emily B, Brink, Thaddeus S, Bergson, Pamela, Voigt, Mark M, Cook, Sean P

“…P2X3 receptors desensitize within 100 ms of channel activation, yet recovery from desensitization requires several minutes. The molecular basis for this slow…”
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Gain and Loss of Channel Function by Alanine Substitutions in the Transmembrane Segments of the Rat ATP-Gated P2X2 Receptor by Li, Zhiyuan, Migita, Keisuke, Samways, Damien S. K, Voigt, Mark M, Egan, Terrance M

“…ATP opens ionotropic P2X channels through a process that is poorly understood. We made an array of mutant rat P2X2 channels containing unique alanine…”
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Polar Residues of the Second Transmembrane Domain Influence Cation Permeability of the ATP-gated P2X2 Receptor by Migita, Keisuke, Haines, William R., Voigt, Mark M., Egan, Terrance M.

“…P2X receptors are simple polypeptide channels that mediate fast purinergic depolarizations in both nerve and muscle. Although the depolarization results mainly…”
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Ectodermal P2X receptor function plays a pivotal role in craniofacial development of the zebrafish by Kucenas, Sarah, Cox, Jane A., Soto, Florentina, LaMora, Angela, Voigt, Mark M.

“…P2X receptors are non-selective cation channels operated by extracellular ATP. Currently, little is known concerning the functions of these receptors during…”
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A Domain Contributing to the Ion Channel of ATP-Gated P2X2 Receptors Identified by the Substituted Cysteine Accessibility Method by Egan, Terrance M, Haines, William R, Voigt, Mark M

“…P2X receptors are a family of ATP-gated ion channels thought to have intracellular N and C termini and two transmembrane segments separating a large…”
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Co-expression of P2X1 and P2X5 receptor subunits reveals a novel ATP-gated ion channel by Torres, G E, Haines, W R, Egan, T M, Voigt, M M

“…P2X receptors are a family of ion channels gated by extracellular ATP. Each member of the family can form functional homomeric channels, but only P2X2 and P2X3…”
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A zebrafish SKIV2L2-enhancer trap line provides a useful tool for the study of peripheral sensory circuit development by Cox, Jane A., McAdow, Anthony R., Dinitz, Amy E., McCallion, Andrew S., Johnson, Stephen L., Voigt, Mark M.

“…► Tg(SKIV2L2:gfp) j1775 is a zebrafish enhancer trap line that labels sensory neurons. ► GFP expression starts soon after neurogenesis and is maintained into…”
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Identification of a Domain Involved in ATP-gated Ionotropic Receptor Subunit Assembly by Torres, G E, Egan, T M, Voigt, M M

“…P2X receptors are ATP-gated ion channels found in a variety of tissues and cell types. Seven different subunits (P2X 1 -P2X 7 ) have been molecularly cloned…”
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N-Linked Glycosylation Is Essential for the Functional Expression of the Recombinant P2X2 Receptor by Torres, Gonzalo E, Egan, Terrance M, Voigt, Mark M

“…P2X receptors are integral membrane proteins that belong to the growing family of transmitter-gated ion channels. The extracellular domain of these receptors…”
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Molecular structure of P2X receptors by Egan, Terrance M, Cox, Jane A, Voigt, Mark M

“…P2X receptors are ligand-gated ion channels that transduce many of the physiological effects of extracellular ATP. There has been a dramatic increase in…”
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The First Transmembrane Domain of the P2X Receptor Subunit Participates in the Agonist-induced Gating of the Channel by Haines, William R., Migita, Keisuke, Cox, Jane A., Egan, Terrance M., Voigt, Mark M.

“…Based on pharmacological properties, the P2X receptor family can be subdivided into those homo-oligomers that are sensitive to the ATP analog αβ-methylene…”
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On the Contribution of the First Transmembrane Domain to Whole-Cell Current through an ATP-Gated Ionotropic P2X Receptor by Haines, William R, Voigt, Mark M, Migita, Keisuke, Torres, Gonzalo E, Egan, Terrance M

“…Scanning cysteine mutagenesis was used to identify potential pore-forming residues in and around the first transmembrane domains of ionotropic P2X(2) receptor…”
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