Search Results - "Vohra, Pawan"

TRPC3 regulates release of brain-derived neurotrophic factor from human airway smooth muscle by Vohra, Pawan K., Thompson, Michael A., Sathish, Venkatachalem, Kiel, Alexander, Jerde, Calvin, Pabelick, Christina M., Singh, Brij B., Prakash, Y.S.

“…Exogenous brain-derived neurotrophic factor (BDNF) enhances Ca2+ signaling and cell proliferation in human airway smooth muscle (ASM), especially with…”
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Adventitial transduction of lentivirus-shRNA-VEGF-A in arteriovenous fistula reduces venous stenosis formation by Yang, Binxia, Janardhanan, Rajiv, Vohra, Pawan, Greene, Eddie L, Bhattacharya, Santanu, Withers, Sarah, Roy, Bhaskar, Nieves Torres, Evelyn C, Mandrekar, Jaywant, Leof, Edward B, Mukhopadhyay, Debabrata, Misra, Sanjay

“…Venous neointimal hyperplasia (VNH) causes hemodialysis vascular access failure. Here we tested whether VNH formation occurs in part due to local vessel…”
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Expression of Profibrotic Genes in a Murine Remnant Kidney Model by Yang, Binxia, MD, PhD, Vohra, Pawan K., PhD, Janardhanan, Rajiv, PhD, Misra, Khamal D., BS, Misra, Sanjay, MD

“…Abstract Purpose To test the hypothesis that there is increased expression of several profibrotic genes, including matrix metalloproteinase (MMP)-2 and MMP-9…”
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Dopamine inhibits pulmonary edema through the VEGF-VEGFR2 axis in a murine model of acute lung injury by Vohra, Pawan K, Hoeppner, Luke H, Sagar, Gunisha, Dutta, Shamit K, Misra, Sanjay, Hubmayr, Rolf D, Mukhopadhyay, Debabrata

“…The neurotransmitter dopamine and its dopamine receptor D2 (D2DR) agonists are known to inhibit vascular permeability factor/vascular endothelial growth factor…”
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Analysis of ErbB Receptors in Pulmonary Carcinoid Tumors by RICKMAN, Otis B, VOHRA, Pawan K, SANYAL, Bharati, VRANA, Julie A, AUBRY, Marie-Christine, WIGLE, Dennis A, THOMAS, Charles F

“…Purpose: This study aimed to investigate the expression of the ErbB family of receptor tyrosine kinases in pulmonary typical carcinoid and atypical carcinoid…”
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NHERF-2 maintains endothelial homeostasis by Bhattacharya, Resham, Wang, Enfeng, Dutta, Shamit K., Vohra, Pawan K., E, Guangqi, Prakash, Y.S., Mukhopadhyay, Debabrata

“…The Na+/H+ exchanger regulatory factor-2 (NHERF-2) is an integral component of almost all endothelial cells (ECs), yet its endothelial function is not known…”
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Targeting GIPC/Synectin in Pancreatic Cancer Inhibits Tumor Growth by Muders, Michael H, Vohra, Pawan K, Dutta, Shamit K, Wang, Enfeng, Ikeda, Yasuhiro, Wang, Ling, Udugamasooriya, D Gomika, Memic, Adnan, Rupasinghe, Chamila N, Rupashinghe, Chamila N, Baretton, Gustavo B, Aust, Daniela E, Langer, Silke, Datta, Kaustubh, Simons, Michael, Spaller, Mark R, Mukhopadhyay, Debabrata

“…Purpose: Various studies have shown the importance of the GAIP interacting protein, COOH-terminus (GIPC, also known as Synectin) as a central adaptor molecule…”
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Cloning and Characterization of CYP51 from Mycobacterium avium by Pietila, Michael P, Vohra, Pawan K, Sanyal, Bharati, Wengenack, Nancy L, Raghavakaimal, Sreekumar, Thomas, Charles F., Jr

“…Mycobacterium avium complex (MAC) causes chronic lung disease in immunocompetent people and disseminated infection in patients with AIDS. MAC is intrinsically…”
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Complementation and characterization of the Pneumocystis carinii MAPK, PCM by Vohra, Pawan K., Puri, Veenu, Thomas, Charles F.

“…Mitogen-activated protein kinase (MAPK) pathways transfer environmental signals into intracellular events such as proliferation and differentiation. Fungi…”
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Expression analysis of PCSTE3, a putative pheromone receptor from the lung pathogenic fungus Pneumocystis carinii by Vohra, Pawan K, Park, John G, Sanyal, Bharati, Thomas, Charles F

“…The fungal pathogen Pneumocystis carinii remains the most prevalent opportunistic infection in patients infected with HIV. Fungal pheromone receptors are seven…”
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Characterization of a lanosterol 14 alpha-demethylase from Pneumocystis carinii by Morales, Ian J, Vohra, Pawan K, Puri, Veenu, Kottom, Theodore J, Limper, Andrew H, Thomas, Jr, Charles F

“…Pneumocystis carinii (PC) causes severe pneumonia in immunocompromised patients. PC is intrinsically resistant to treatment with azole antifungal medications…”
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Biochemical requirements for PCBCK1 kinase activity, the Pneumocystis carinii MEKK involved in cell wall integrity by Vohra, Pawan K., Sanyal, Bharati, Thomas, Charles F.

“…Abstract Fungal cell wall assembly is a complicated process involving multiple enzymes and coordinated signaling pathways. The cell wall integrity MAPK pathway…”
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Pneumocystis carinii STE11, an HMG-box protein, is phosphorylated by the mitogen activated protein kinase PCM by Vohra, Pawan K., Puri, Veenu, Kottom, Theodore J., Limper, Andrew H., Thomas, Charles F.

“…A pheromone-induced mitogen activated protein kinase (MAPK) pathway controls mating in fungi by regulating gene transcription. In the opportunistic fungus…”
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Pneumocystis carinii BCK1 functions in a mitogen-activated protein kinase cascade regulating fungal cell-wall assembly by Thomas, Charles F., Vohra, Pawan K., Park, John G., Puri, Veenu, Limper, Andrew H., Kottom, Theodore J.

“…Pneumocystis pneumonia remains the most common AIDS-defining opportunistic infection in people with HIV. The process by which Pneumocystis carinii constructs…”
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Degumming of buel (Grewia optiva) bast fibres by pectinolytic enzyme from Bacillus sp. DT7 by KASHAYP, Des R, VOHRA, Pawan K, SONI, Sanjeev K, TEWARI, Rupinder

“…An alkalophilic and thermotolerant, pectinase-producing Bacillus sp. DT7 effectively removed pectic substances from buel (Grewia optiva) bast fibres. A novel…”
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Simvastatin reduces venous stenosis formation in a murine hemodialysis vascular access model by Janardhanan, Rajiv, Yang, Binxia, Vohra, Pawan, Roy, Bhaskar, Withers, Sarah, Bhattacharya, Santanu, Mandrekar, Jaywant, Kong, Hyunjoon, Leof, Edward B, Mukhopadhyay, Debabrata, Misra, Sanjay

“…Venous neointimal hyperplasia (VNH) is responsible for hemodialysis vascular access malfunction. Here we tested whether VNH formation occurs, in part, due to…”
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Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2 by Sinha, Sutapa, Vohra, Pawan Kumar, Bhattacharya, Resham, Dutta, Shamit, Sinha, Shirshendu, Mukhopadhyay, Debabrata

“…Vascular endothelial growth factor (VEGF)-induced receptor phosphorylation is the crucial step for initiating downstream signaling pathways that lead to…”
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Caveolin-1 knockout mice exhibit airway hyperreactivity by Aravamudan, Bharathi, VanOosten, Sarah K, Meuchel, Lucas W, Vohra, Pawan, Thompson, Michael, Sieck, Gary C, Prakash, Y S, Pabelick, Christina M

“…Caveolae are flask-shaped plasma membrane invaginations expressing the scaffolding caveolin proteins. Although caveolins have been found in endothelium and…”
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Revealing the role of phospholipase Cβ3 in the regulation of VEGF-induced vascular permeability by Hoeppner, Luke H., Phoenix, Kathryn N., Clark, Karl J., Bhattacharya, Resham, Gong, Xun, Sciuto, Tracey E., Vohra, Pawan, Suresh, Sandip, Bhattacharya, Santanu, Dvorak, Ann M., Ekker, Stephen C., Dvorak, Harold F., Claffey, Kevin P., Mukhopadhyay, Debabrata

“…VEGF induces vascular permeability (VP) in ischemic diseases and cancer, leading to many pathophysiological consequences. The molecular mechanisms by which…”
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A lipid-modified estrogen derivative that treats breast cancer independent of estrogen receptor expression through simultaneous induction of autophagy and apoptosis by Sinha, Sutapa, Roy, Sayantani, Reddy, Bathula Surendar, Pal, Krishnendu, Sudhakar, Godeshala, Iyer, Seethalakshmi, Dutta, Shamit, Wang, Enfeng, Vohra, Pawan Kumar, Roy, Karnati Rammohan, Reddanna, Pallu, Mukhopadhyay, Debabrata, Banerjee, Rajkumar

“…It is a challenge to develop a universal single drug that can treat breast cancer at single- or multiple-stage complications, yet remains nontoxic to normal…”
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