Search Results - "Vohra, Aliasgar"

HSP60 knockdown exerts differential response in endothelial cells and monocyte derived macrophages during atherogenic transformation by Shirsath, Kavita, Joshi, Apeksha, Vohra, Aliasgar, Devkar, Ranjitsinh

“…Ectopic expression of HSP60 in vascular cells is known to activate auto-immune response that is critical to atherogenic initiation. However, the pathogenic…”
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Carbon monoxide releasing molecule-A1 improves nonalcoholic steatohepatitis via Nrf2 activation mediated improvement in oxidative stress and mitochondrial function by Upadhyay, Kapil K., Jadeja, Ravirajsinh N., Vyas, Hitarthi S., Pandya, Bhaumik, Joshi, Apeksha, Vohra, Aliasgar, Thounaojam, Menaka C., Martin, Pamela M., Bartoli, Manuela, Devkar, Ranjitsinh V.

“…Nuclear factor-erythroid 2 related factor 2 (Nrf2)-mediated signaling plays a central role in maintaining cellular redox homeostasis of hepatic cells. Carbon…”
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Chronic photoperiodic manipulation induced chronodisruption upregulates HSP60 during early pro-atherogenic remodeling in thoracic aorta of C57BL/6J mice by Shirsath, Kavita, Joshi, Apeksha, Vohra, Aliasgar, Devkar, Ranjitsinh

“…Background Circadian disruption is often associated with aggravation of atherosclerosis; however, the pathophysiological mechanisms underlying atherogenic…”
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Carbon monoxide releasing molecule A-1 attenuates acetaminophen-mediated hepatotoxicity and improves survival of mice by induction of Nrf2 and related genes by Upadhyay, Kapil K., Jadeja, Ravirajsinh N., Thadani, Jaymesh M., Joshi, Apeksha, Vohra, Aliasgar, Mevada, Vishal, Patel, Rajesh, Khurana, Sandeep, Devkar, Ranjitsinh V.

“…Acute liver injury is frequently associated with oxidative stress. Here, we investigated the therapeutic potential of carbon monoxide releasing molecule A-1…”
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CORM-A1 Alleviates Pro-Atherogenic Manifestations via miR-34a-5p Downregulation and an Improved Mitochondrial Function by Vyas, Hitarthi S, Jadeja, Ravirajsinh N, Vohra, Aliasgar, Upadhyay, Kapil K, Thounaojam, Menaka C, Bartoli, Manuela, Devkar, Ranjitsinh V

“…Atherogenesis involves multiple cell types undergoing robust metabolic processes resulting in mitochondrial dysfunction, elevated reactive oxygen species…”
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Melatonin-primed ADMSCs elicit an efficacious therapeutic response in improving high-fat diet induced non-alcoholic fatty liver disease in C57BL/6J mice by Vohra, Aliasgar Hatimbhai, Upadhyay, Kapil Kumar, Joshi, Apeksha Suhas, Vyas, Hitarthi Swetang, Thadani, Jaymesh, Devkar, Ranjitsinh Vijaysinh

“…Background Stem cells are widely used for therapy including treatment of liver damage. Adipose-derived mesenchymal stem cells (ADMSCs) administered to treat…”
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Abstract 1155 KH-type Splicing Regulatory Protein mediated upregulation of miR-34a negatively impacts lipid homeostasis in hepatocytes by Karnik, Rhydham, Vyas, Hitarthi, Vohra, Aliasgar, Shah, Helly, Devkar, Ranjitsinh

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Sa1592 CIRCADIAN DESYNCHRONY ALTERS LIPIDOMIC SIGNATURE IN C57BL/6J MICE: A STUDY WITH SERUM LC-QTOF-MS PROFILING by Dalvi, Nilay, Vohra, Aliasgar H., Karnik, Rhydham, Devkar, Ranjitsingh V.

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Carbon nanotube embedded cyclodextrin polymer derived injectable nanocarrier: A multiple faceted platform for stimulation of multi-drug resistance reversal by Das, Manita, Nariya, Pratik, Joshi, Apeksha, Vohra, Aliasgar, Devkar, Ranjitsinh, Seshadri, Sriram, Thakore, Sonal

“…[Display omitted] •Simple and facile synthesis of CNT embedded cyclodextrin polymer derived injectable.•Synergistic CCT, PT & anti-angiogenesis assisted MDR…”
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Melatonin induces Nrf2‐HO‐1 reprogramming and corrections in hepatic core clock oscillations in Non‐alcoholic fatty liver disease by Joshi, Apeksha, Upadhyay, Kapil K., Vohra, Aliasgar, Shirsath, Kavita, Devkar, Ranjitsinh

“…Melatonin pleiotropically regulates physiological events and has a putative regulatory role in the circadian clock desynchrony‐mediated Non‐alcoholic fatty…”
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Abstract 2026: Epigenetic and transcriptional regulation of CXCR4 by circadian clock regulated miRNAs in human monocyte derived macrophages by Karnik, Rhydham, Vohra, Aliasgar, Vyas, Hitarthi, Devkar, Ranjitsinh

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miR34a-5p impedes CLOCK expression in chronodisruptive C57BL/6J mice and potentiates pro-atherogenic manifestations by Vyas, Hitarthi, Vohra, Aliasgar, Upadhyay, Kapil, Thounaojam, Menaka, Jadeja, Ravirajsinh, Dalvi, Nilay, Bartoli, Manuela, Devkar, Ranjitsinh

“…Altered circadian rhythms underlie manifestation of several cardiovascular disorders, however a little is known about the mediating biomolecules. Multiple…”
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Sa1590 CIRCADIAN SHIFTS IN STEATOTIC LIVER ALTERS INTRA AND EXTRA-HEPATIC OSCILLATIONS OF MIR 122 by Devkar, Ranjitsingh V., Karnik, Rhydham, Dalvi, Nilay, Kulshrestha, Shruti, Vohra, Aliasgar H.

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EP1219: MELATONIN IMPROVES GUT DYSBIOSIS IN HIGH FAT-HIGH FRUCTOSE DIET MODEL OF NAFLD AND/OR PHOTOPERIOD INDUCED CHRONODISRUPTION IN C57BL/6J MICE by Karnik, Rhydham, Vohra, Aliasgar, Vyas, Hitarthi, Dalvi, Nilay, Kulshrestha, Shruti, Devkar, Ranjitsinh

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EP115 NOCTURNIN: A PUTATIVE TARGET OF MELATONIN MEDIATED IMPROVEMENT IN EXPERIMENTALLY INDUCED NAFLD by Kulshrestha, Shruti, Joshi, Apeksha, Vohra, Aliasgar H., Karnik, Rhydham, Dalvi, Nilay, Christian, Felix, Kumar, Ashutosh, Devkar, Ranjitsingh V.

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Melatonin-mediated corrective changes in gut microbiota of experimentally chronodisrupted C57BL/6J mice by Vohra, Aliasgar, Karnik, Rhydham, Desai, Mansi, Vyas, Hitarthi, Kulshrestha, Shruti, Upadhyay, Kapil Kumar, Koringa, Prakash, Devkar, Ranjitsinh

“…Chronic consumption of a high-calorie diet coupled with an altered sleep-wake cycle causes disruption of circadian clock that can impact the gut microbiome…”
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Diet/photoperiod mediated changes in cerebellar clock genes causes locomotor shifts and imperative changes in BDNF-TrkB pathway by Karnik, Rhydham, Vohra, Aliasgar, Khatri, Mahamadtezib, Dalvi, Nilay, Vyas, Hitarthi S., Shah, Helly, Gohil, Sujitsinh, Kanojiya, Smit, Devkar, Ranjitsinh

“…[Display omitted] •Diet/photoperiod mediated circadian desynchrony causes subtle deficit in locomotor function.•Purkinje cell derangement in treated mice…”
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Organoruthenium (II) complexes featuring pyrazole‐linked thiosemicarbazone ligands: Synthesis, DNA/BSA interactions, molecular docking, and cytotoxicity studies by Khanvilkar, Priyanka, Dash, Soumya R., Banerjee, Devjani, Vohra, Aliasgar, Devkar, Ranjitsinh, Chakraborty, Debjani

“…A series of pyrazol‐derived thiosemicarbazone ligands (L1–L4) were synthesized and reacted with [Ru(p‐cymene)(μ‐Cl)Cl]2 to yield a series of “piano‐stool”‐type…”
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Ionic Liquid-Mediated Preparation of Noncytotoxic Hemocompatible Stable DNA−ε-Poly- l -lysine Polyplexes: A New Sustainable Approach for the Bulk Production of Potential Nonviral Vectors for Gene Delivery Applications by Bhatt, Jitkumar, Sequeira, Rosy Alphons, Vohra, Aliasgar, Devkar, Ranjitsinh Vijaysingh, Maity, Tapan Kumar, Prasad, Kamalesh

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Hepatic-Hippocampal Crosstalk in Circadian Desynchrony and Non-Alcoholic Steatohepatitis by Hatimbhai, Vohra Aliasgar

“…Circadian clock modulation impairs cognitive performance, deficits in learning, memory and spontaneous locomotor activity. In mice, high fat high fructose diet…”
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