Search Results - "Vogt, PH"

AZF deletions and Y chromosomal haplogroups: history and update based on sequence by Vogt, Peter H

“…AZF deletions are genomic deletions in the euchromatic part of the long arm of the human Y chromosome (Yq11) associated with azoospermia or severe…”
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Azoospermia factor (AZF) in Yq11: towards a molecular understanding of its function for human male fertility and spermatogenesis by Vogt, Peter H

“…The Y chromosomal azoospermia factor (AZF) is essential for human spermatogenesis. It has been mapped by molecular deletion analyses to three subintervals in…”
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Developmental expression of POU5F1 (OCT‐3/4) in normal and dysgenetic human gonads by Rajpert‐De Meyts, Ewa, Hanstein, Regina, Jørgensen, Niels, Græm, Niels, Vogt, Peter H., Skakkebæk, Niels E.

“…BACKGROUND: To investigate how long fetal germ cells retain pluripotency, which may be linked to their ability to transform into histologically variable…”
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A Large AZFc Deletion Removes DAZ3/DAZ4 and Nearby Genes from Men in Y Haplogroup N by Fernandes, S., Paracchini, S., Meyer, L.H., Floridia, G., Tyler-Smith, C., Vogt, P.H.

“…Deletion of the entire AZFc locus on the human Y chromosome leads to male infertility. The functional roles of the individual gene families mapped to AZFc are,…”
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The AZFa gene DBY (DDX3Y) is widely transcribed but the protein is limited to the male germ cells by translation control by Ditton, H.J., Zimmer, J., Kamp, C., Rajpert-De Meyts, E., Vogt, P.H.

“…We explored the function of the human DEAD-box Y RNA helicase DBY (DDX3Y) gene located in the (AZFa) region on the human Y chomosome (Yq11.21). Deletion of…”
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Two long homologous retroviral sequence blocks in proximal Yq11 cause AZFa microdeletions as a result of intrachromosomal recombination events by KAMP, Christine, HIRSCHMANN, Peter, VOSS, Hartmut, HUELLEN, Karin, VOGT, Peter H

“…We mapped the breakpoints of the AZoospermia factor a (AZFa) microdeletion located in proximal Yq11 in six men with complete germ cell aplasia, i.e. Sertoli…”
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Multiplex PCR: critical parameters and step-by-step protocol by Henegariu, O, Heerema, N A, Dlouhy, S R, Vance, G H, Vogt, P H

“…By simultaneously amplifying more than one locus in the same reaction, multiplex PCR is becoming a rapid and convenient screening assay in both the clinical…”
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Variable expression of the Fragile X Mental Retardation 1 (FMR1) gene in patients with premature ovarian failure syndrome is not dependent on number of (CGG) sub(n) triplets in exon 1 by Schuettler, J, Peng, Z, Zimmer, J, Sinn, P, von Hagens, C, Strowitzki, T, Vogt, PH

“…BACKGROUND Increased expression of the Fragile X Mental Retardation 1 (FMR1) gene in blood cells has been claimed to be associated with variable (CGG) sub(n)…”
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Human Y Chromosome Azoospermia Factors (AZF) Mapped to Different Subregions in Yq11 by Vog, P. H., Edelmann, A., Kirsch, S., Henegariu, O., Hirschmann, P., Kiesewetter, F., Köhn, F. M., Schill, W. B., Farah, S., Ramos, C., Hartmann, M., Hartschuh, W., Meschede, D., Behre, H. M., Castel, A., Nieschlag, E., Weidner, W., Gröne, H-J., Jung, A., Engel, W., Haidl, G.

“…In a large collaborative screening project, 370 men with idiopathic azoospermia or severe oligozoospermia were analysed for deletions of 76 DNA loci in Yq11…”
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RAN-Translation in fragile X associated Premature Ovarian Insufficiency (FXPOI) FMRpolyG as predictive tool? by Nguyen, XP, Messmer, B, Hinderhofer, K, Strowitzki, T, Vogt, PH, Rehnitz, J

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Human chromosome deletions in Yq11, AZf candidate genes and male infertility : history and update by VOGT, P. H

“…Human chromosome deletions in Yq11 seem to occur frequently as de novo mutation events in men with idiopathic azoospermia or severe oligozoospermia. However,…”
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Genomic heterogeneity and instability of the AZF locus on the human Y chromosome by Vogt, Peter H.

“…The spermatogenesis locus azoospermia factor (AZF) in Yq11 has been mapped to three microdeletion intervals designated as AZFa, AZFb, and AZFc. They are caused…”
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Premature ovarian insufficiency/failure syndrome“ (POI/POF) by Rehnitz, J., Strowitzki, T., Vogt, PH

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High frequency of DAZ1/DAZ2 gene deletions in patients with severe oligozoospermia by Fernandes, S., Huellen, K., Goncalves, J., Dukal, H., Zeisler, J., Rajpert De Meyts, E., Skakkebaek, N.E., Habermann, B., Krause, W., Sousa, M., Barros, A., Vogt, P.H.

“…Deletions of the DAZ gene family in distal Yq11 are always associated with deletions of the azoospermia factor c (AZFc) region, which we now estimate extends…”
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FMR1 und mTOR/AKT Signalweg in humanen Granulosazellen: Funktion und Interaktion in der Follikulogenese by Rehnitz, J, Capp, E, Messmer, B, Germeyer, A, Dietrich, JE, Strowitzki, T, Vogt, PH

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Premature ovarian failure (POF) syndrome: towards the molecular clinical analysis of its genetic complexity by Fassnacht, W, Mempel, A, Strowitzki, T, Vogt, P H

“…The Premature Ovarian Failure (POF) syndrome is a very heterogeneous clinical disorder due probably to the complex genetic networks controlling human…”
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High deletion frequency of the complete AZFa sequence in men with Sertoli-cell-only syndrome by Kamp, C., Huellen, K., Fernandes, S., Sousa, M., Schlegel, P.N., Mielnik, A., Kleiman, S., Yavetz, H., Krause, W., Küpker, W., Johannisson, R., Schulze, W., Weidner, W., Barros, A., Vogt, P.H.

“…We have developed a rapid screening protocol for deletion analysis of the complete AZFa sequence (i.e. 792 kb) on the Y chromosome of patients with idiopathic…”
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The azoospermia factor (AZF) of the human Y chromosome in Yq11: function and analysis in spermatogenesis by Vogt, P H, Edelmann, A, Hirschmann, P, Köhler, M R

“…Different Y mutations in Yq11 occurring de novo in sterile males were first described 19 years ago. Since the phenotype of the patients was always associated…”
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FMR1-Expression und mTOR/AKT-Signalkaskade – zwei potentielle Teamplayer der Follikulogenesekontrolle in humanen Granulosazellen by Rehnitz, J, Alcoba, DD, Brum, IS, Strowitzki, T, Vogt, PH

“…Zielsetzung: Analyse einer möglicherweise gekoppelten Expression von FMR1 /FMRP (Fragile X Mental Retardation 1 Gen und Protein) und der Schlüsselgene des…”
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Expression of RBM in the Nuclei of Human Germ Cells is Dependent on a Critical Region of the Y Chromosome Long Arm by Elliott, D. J., Millar, M. R., Oghene, K., Ross, A., Kiesewetter, F., Pryor, J., McIntyre, M., Hargreave, T. B., Saunders, P. T. K., Vogt, P. H., Chandley, A. C., Cooke, H.

“…The association of abnormal spermatogenesis in men with Y chromosome deletions suggests that genes important for spermatogenesis have been removed from these…”
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