Search Results - "Vogt, Hartmut"
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Effects of allopurinol on 6-mercaptopurine metabolism in unselected patients with pediatric acute lymphoblastic leukemia: a prospective phase II study
Published in Haematologica (Roma) (01-09-2024)“…Allopurinol can be used in maintenance therapy (MT) for pediatric acute lymphoblastic leukemia (ALL) to mitigate hepatic toxicity in patients with skewed…”
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In-depth analysis of transcriptomes in ovarian cortical follicles from children and adults reveals interfollicular heterogeneity
Published in Nature communications (21-08-2024)“…The ovarian cortical reserve of follicles is vital for fertility. Some medical treatments are toxic to follicles, leading to premature ovarian insufficiency…”
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Implementing data on targeted therapy from the INFORM registry platform for children with relapsed cancer in Sweden
Published in Frontiers in oncology (2024)“…Advances in treatment of childhood malignancies have improved overall cure rates to 80%. Nevertheless, cancer is still the most common cause of childhood…”
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Euphorbia tirucalli L.-comprehensive characterization of a drought tolerant plant with a potential as biofuel source
Published in PloS one (03-05-2013)“…Of late, decrease in mineral oil supplies has stimulated research on use of biomass as an alternative energy source. Climate change has brought problems such…”
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Pertussis immunization in infancy and adolescent asthma medication
Published in Pediatrics (Evanston) (01-10-2014)“…Childhood immunization may influence the development of asthma, possibly due to lack of infections or a shift in the T-helper cell type 1/T-helper cell type…”
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Preterm Birth and Inhaled Corticosteroid Use in 6- to 19-Year-Olds: A Swedish National Cohort Study
Published in Pediatrics (Evanston) (01-06-2011)“…Preterm birth is associated with respiratory morbidity later in life, including asthma. Previous studies have mainly focused on asthma in early childhood in…”
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Spermatogonia Loss Correlates with LAMA 1 Expression in Human Prepubertal Testes Stored for Fertility Preservation
Published in Cells (Basel, Switzerland) (2021)“…Fertility preservation for male childhood cancer survivors not yet capable of producing mature spermatozoa, relies on experimental approaches such as…”
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Asthma Heredity, Cord Blood IgE and Asthma-Related Symptoms and Medication in Adulthood: A Long-Term Follow-Up in a Swedish Birth Cohort
Published in PloS one (21-06-2013)“…Cord blood IgE has previously been studied as a possible predictor of asthma and allergic diseases. Results from different studies have been contradictory, and…”
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TET2 as a tumor suppressor and therapeutic target in T-cell acute lymphoblastic leukemia
Published in Proceedings of the National Academy of Sciences - PNAS (24-08-2021)“…Pediatric T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy resulting from overproduction of immature T-cells in the thymus and is…”
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Spermatogonial quantity in human prepubertal testicular tissue collected for fertility preservation prior to potentially sterilizing therapy
Published in Human reproduction (Oxford) (01-09-2018)“…Abstract STUDY QUESTION Does chemotherapy exposure (with or without alkylating agents) or primary diagnosis affect spermatogonial quantity in human prepubertal…”
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Loss of Chromosome Y in Neuroblastoma Is Associated With High‐Risk Disease, 11q‐Deletion, and Telomere Maintenance
Published in Genes chromosomes & cancer (01-07-2024)“…ABSTRACT Neuroblastoma (NB) is a heterogeneous childhood cancer with a slightly higher incidence in boys than girls, with the reason for this gender disparity…”
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Low numbers of COVID‐19 in Swedish pediatric oncology patients during the first pandemic year despite an open society
Published in Pediatric blood & cancer (01-10-2022)“…Background Sweden adopted a different strategy than many other countries to combat the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic…”
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Haemostasis during early treatment of childhood acute lymphoblastic leukaemia with the ALLTogether protocol
Published in ACTA PAEDIATRICA (2024)Get full text
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A survey on thromboprophylaxis and coagulation assessment in children and young adults with acute lymphoblastic leukaemia (ALL) in the Nordic and Baltic countries: Different practices of assessment and management
Published in British journal of haematology (01-10-2022)“…Summary Patients undergoing treatment for acute lymphoblastic leukaemia (ALL) are at risk of coagulopathy, especially thromboembolism. We conducted a survey on…”
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Reference standards for follicular density in ovarian cortex from birth to sexual maturity
Published in Reproductive biomedicine online (01-10-2023)“…•Establishment of a reference model for cortical follicular density for ages 0–25 years.•Average Z-score indicates normal reserve in patients exposed to…”
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A reassessment of DNA-immunoprecipitation-based genomic profiling
Published in Nature methods (01-07-2018)“…DNA immunoprecipitation followed by sequencing (DIP-seq) is a common enrichment method for profiling DNA modifications in mammalian genomes. However, the…”
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Could Dissimilar Phenotypic Effects of ACTB Missense Mutations Reflect the Actin Conformational Change Two Novel Mutations and Literature Review
Published in Molecular syndromology (01-01-2019)“…The beta-actin gene encodes 1 of 6 different actin proteins. De novo heterozygous missense mutations in ACTB have been identified in patients with…”
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Migration and asthma medication in international adoptees and immigrant families in Sweden
Published in Clinical and experimental allergy (01-08-2011)“…Summary Background Studies of asthma in migrant populations illustrate the effects of environmental changes. Objective In this register study we investigated…”
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Diagnostic yield and clinical impact of germline sequencing in children with CNS and extracranial solid tumors—a nationwide, prospective Swedish study
Published in The Lancet regional health. Europe (2024)“…Childhood cancer predisposition (ChiCaP) syndromes are increasingly recognized as contributing factors to childhood cancer development. Yet, due to variable…”
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Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With Cancer
Published in JCO precision oncology (01-01-2023)“…Several studies have indicated that broad genomic characterization of childhood cancer provides diagnostically and/or therapeutically relevant information in…”
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