Search Results - "Vogler, Birgit"
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Petasin and isopetasin reduce CGRP release from trigeminal afferents indicating an inhibitory effect on TRPA1 and TRPV1 receptor channels
Published in Journal of headache and pain (13-04-2021)“…Background Butterbur root extract with its active ingredients petasin and isopetasin has been used in the prophylactic treatment of migraine for years, while…”
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2
CGRP outflow into jugular blood and cerebrospinal fluid and permeance for CGRP of rat dura mater
Published in Journal of headache and pain (08-09-2021)“…Background Calcitonin gene-related peptide (CGRP) is released from activated meningeal afferent fibres in the cranial dura mater, which likely accompanies…”
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The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats
Published in International journal of molecular sciences (01-09-2023)“…Treatment with the anti-CGRP antibody fremanezumab is successful in the prevention of chronic and frequent episodic migraine. In preclinical rat experiments,…”
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4
Glycerol Trinitrate Acts Downstream of Calcitonin Gene-Related Peptide in Trigeminal Nociception-Evidence from Rodent Experiments with Anti-CGRP Antibody Fremanezumab
Published in Cells (Basel, Switzerland) (01-04-2024)“…Calcitonin gene-related peptide (CGRP) and nitric oxide (NO) have been recognized as important mediators in migraine but their mechanisms of action and…”
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The Anti-CGRP Antibody Fremanezumab Lowers CGRP Release from Rat Dura Mater and Meningeal Blood Flow
Published in Cells (Basel, Switzerland) (28-05-2022)“…Monoclonal antibodies directed against the neuropeptide calcitonin gene-related peptide (CGRP) belong to a new generation of therapeutics that are effective in…”
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Semi-Automated Recording of Facial Sensitivity in Rat Demonstrates Antinociceptive Effects of the Anti-CGRP Antibody Fremanezumab
Published in Neurology international (29-04-2023)“…Migraine pain is frequently accompanied by cranial hyperalgesia and allodynia. Calcitonin gene-related peptide (CGRP) is implicated in migraine pathophysiology…”
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CGRP measurements in human plasma - a methodological study
Published in Cephalalgia (01-11-2021)“…Calcitonin gene-related peptide plasma levels have frequently been determined as a biomarker for primary headaches. However, published data is often…”
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Meningeal blood flow is controlled by H2S‐NO crosstalk activating a HNO‐TRPA1‐CGRP signalling pathway
Published in British journal of pharmacology (01-02-2016)“…Background and Purpose Meningeal blood flow is controlled by CGRP released from trigeminal afferents and NO mainly produced in arterial endothelium. The…”
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High‐dose phenylephrine increases meningeal blood flow through TRPV1 receptor activation and release of calcitonin gene‐related peptide
Published in European journal of pain (01-02-2020)“…Background The α1‐adrenoceptor agonist, phenylephrine, is used at high concentrations as a mydriatic agent and for the treatment of nasal congestion. Among its…”
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Meningeal blood flow is controlled by H 2 S‐NO crosstalk activating a HNO ‐ TRPA 1‐ CGRP signalling pathway
Published in British journal of pharmacology (01-02-2016)“…Background and Purpose Meningeal blood flow is controlled by CGRP released from trigeminal afferents and NO mainly produced in arterial endothelium. The…”
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H^sub 2^S-NO-TRPA1-CGRP signalling controls meningeal blood flow
Published in Neuropeptides (Edinburgh) (01-10-2017)“…Calcitonin gene-related peptide (CGRP) and nitric oxide (NO) released in the dura mater encephali mediate meningeal blood flow elevation possibly linked to the…”
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12
H 2 S-NO-TRPA1-CGRP signalling controls meningeal blood flow
Published in Neuropeptides (Edinburgh) (01-10-2017)Get full text
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13
H2S-NO-TRPA1-CGRP signalling controls meningeal blood flow
Published in Neuropeptides (Edinburgh) (01-10-2017)Get full text
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Meningeal blood flow is controlled by H2 S-NO crosstalk activating a HNO-TRPA1-CGRP signalling pathway
Published in British journal of pharmacology (01-02-2016)“…Meningeal blood flow is controlled by CGRP released from trigeminal afferents and NO mainly produced in arterial endothelium. The vasodilator effect of NO may…”
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