Search Results - "Vogelpoel, Lisa T.C."
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Chemotherapy Alters Monocyte Differentiation to Favor Generation of Cancer-Supporting M2 Macrophages in the Tumor Microenvironment
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Current therapy of gynecologic malignancies consists of platinum-containing chemotherapy. Resistance to therapy is associated with increased levels of…”
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FcγRIIa cross-talk with TLRs, IL-1R, and IFNγR selectively modulates cytokine production in human myeloid cells
Published in Immunobiology (1979) (01-02-2015)“…Abstract Myeloid antigen-presenting cells (APCs) tailor immune responses to the pathogen involved through the production of specific pro- and anti-inflammatory…”
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Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages
Published in Nature communications (13-11-2014)“…M2 macrophages suppress inflammation in numerous disorders, including tumour formation, infection and obesity. However, the exact role of M2 macrophages in the…”
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Control of cytokine production by human fc gamma receptors: implications for pathogen defense and autoimmunity
Published in Frontiers in immunology (24-02-2015)“…Control of cytokine production by immune cells is pivotal for counteracting infections via orchestration of local and systemic inflammation. Although their…”
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FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming
Published in Frontiers in immunology (08-04-2019)“…Antigen-presenting cells (APCs) such as dendritic cells (DCs) are crucial for initiation of adequate inflammatory responses, which critically depends on the…”
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IgG opsonization of bacteria promotes Th17 responses via synergy between TLRs and FcγRIIa in human dendritic cells
Published in Blood (05-07-2012)“…Dendritic cells (DCs) are essential in inducing adaptive immune responses against bacteria by expressing cytokines that skew T-cell responses toward protective…”
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Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells
Published in European journal of immunology (01-11-2018)“…Type I and type III interferons (IFNs) are fundamental for antiviral immunity, but prolonged expression is also detrimental to the host. Therefore, upon viral…”
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