Search Results - "Vogelbaum, M. A."

Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas by van den Bent, MJ, Prof, Wefel, JS, PhD, Schiff, D, MD, Taphoorn, MJB, Prof, Jaeckle, K, MD, Junck, L, MD, Armstrong, T, PhD, Choucair, A, MD, Waldman, AD, PhD, Gorlia, T, MSc, Chamberlain, M, MD, Baumert, BG, MD, Vogelbaum, MA, MD, Macdonald, DR, MD, Reardon, DA, MD, Wen, PY, Prof, Chang, SM, Prof, Jacobs, AH, Prof

“…Summary Although low-grade gliomas (LGG) have a less aggressive course than do high-grade gliomas, the outcome of these tumours is ultimately fatal in most…”
Get full text

Current concepts and newer developments in the treatment of malignant gliomas by Omay, S B, Vogelbaum, M A

“…Primary malignant brain tumors account for only 2% of all adult cancers but they cause a disproportionately high cancer-related disability and death. Survival…”
Get full text

Clinical trial end points for high-grade glioma: the evolving landscape by Reardon, David A., Galanis, Evanthia, DeGroot, John F., Cloughesy, Timothy F., Wefel, Jeffrey S., Lamborn, Kathleen R., Lassman, Andrew B., Gilbert, Mark R., Sampson, John H., Wick, Wolfgang, Chamberlain, Marc C., Macdonald, David R., Mehta, Minesh P., Vogelbaum, Michael A., Chang, Susan M., Van den Bent, Martin J., Wen, Patrick Y.

“…To review the strengths and weaknesses of primary and auxiliary end points for clinical trials among patients with high-grade glioma (HGG). Recent advances in…”
Get full text

Aggressive treatment is appropriate for glioblastoma multiforme patients 70 years old or older: a retrospective review of 206 cases by Scott, Jacob G., Suh, John H., Elson, Paul, Barnett, Gene H., Vogelbaum, Michael A., Peereboom, David M., Stevens, Gene H. J., Elinzano, Heinrich, Chao, Samuel T.

“…Elderly patients have largely been excluded from randomized trials for glioblastoma multiforme (GBM). We reviewed the results of treatment approaches, which…”
Get full text

Successful treatment of vancomycin-resistant enterococcus meningitis with linezolid: Case report and review of the literature by Steinmetz, Michael P, Vogelbaum, Michael A, De Georgia, Michael A, Andrefsky, John C, Isada, Carlos

“…OBJECTIVE To describe the successful treatment of a case of vancomycin-resistant enterococcus meningitis with linezolid. DESIGN Case report and review of the…”
Get full text

Temporal chimeras produced by hypothalamic transplants by Vogelbaum, MA, Menaker, M

“…The expression of locomotor activity by golden hamsters is temporally controlled by circadian oscillators contained within the suprachiasmatic nuclei. A…”
Get full text

Overexpression of bax in human glioma cell lines by VOGELBAUM, M. A, TONG, J. X, PERUGU, R, GUTMANN, D. H, RICH, K. M

“…Cells that lose their ability to undergo apoptosis may promote the development of neoplasms and result in resistance to clinical treatment with DNA-damaging…”
Get full text

Management of uncomplicated skull fractures in children: is hospital admission necessary? by Vogelbaum, M A, Kaufman, B A, Park, T S, Winthrop, A L

“…This study was undertaken to determine the necessity for routine hospital admission of children with skull fractures, a normal neurological exam, a normal head…”
Get more information

Transfection of C6 glioma cells with the bax gene and increased sensitivity to treatment with cytosine arabinoside by VOGELBAUM, M. A, TONG, J. X, HIGASHIKUBO, R, GUTMANN, D. H, RICH, K. M

“…Genes known to be involved in the regulation of apoptosis include members of the bcl-2 gene family, such as inhibitors of apoptosis (bcl-2 and bcl-xl) and…”
Get full text

Convection-enhanced delivery for the treatment of glioblastoma by Vogelbaum, Michael A, Aghi, Manish K

“…Effective treatment of glioblastoma (GBM) remains a formidable challenge. Survival rates remain poor despite decades of clinical trials of conventional and…”
Get full text

OS04.2 First in human study of the Cleveland Multiport Catheter and convection enhanced delivery of topotecan and gadolinium for recurrent GBM: Updated results by Vogelbaum, M. A., Brewer, C.

“…Introduction: Most potential therapeutics fail to reach gliomas at clinically useful concentrations due to presence of the blood-brain and the blood-tumor…”
Get full text

Mutant circadian period as a marker of suprachiasmatic nucleus function by Menaker, M, Vogelbaum, M A

“…Fetal suprachiasmatic nucleus (SCN) tissue transplanted into the third ventricle of hamsters bearing complete SCN lesions restores the circadian locomotor…”
Get more information

Developmental Regulation of Apoptosis in Dorsal Root Ganglion Neurons by Vogelbaum, Michael A, Tong, Jianxin X, Rich, Keith M

“…The survival of dorsal root ganglion (DRG) neurons, both in vivo and in vitro, is dependent on the availability of nerve growth factor (NGF) for a transient…”
Get full text

Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma by Raychaudhuri, Baisakhi, Rayman, Patricia, Ireland, Joanna, Ko, Jennifer, Rini, Brian, Borden, Ernest C., Garcia, Jorge, Vogelbaum, Michael A., Finke, James

“…To assess the accumulation of myeloid-derived suppressor cells (MDSCs) in the peripheral blood of patients with glioma and to define their heterogeneity and…”
Get full text

Liquid biopsy in gliomas: A RANO review and proposals for clinical applications by Soffietti, Riccardo, Bettegowda, Chetan, Mellinghoff, Ingo K, Warren, Katherine E, Ahluwalia, Manmeet S, De Groot, John F, Galanis, Evanthia, Gilbert, Mark R, Jaeckle, Kurt A, Le Rhun, Emilie, Rudà, Roberta, Seoane, Joan, Thon, Niklas, Umemura, Yoshie, Weller, Michael, van den Bent, Martin J, Vogelbaum, Michael A, Chang, Susan M, Wen, Patrick Y

“…There is an extensive literature highlighting the utility of blood-based liquid biopsies in several extracranial tumors for diagnosis and monitoring. The RANO…”
Get full text

P18.54.B DEVELOPMENT AND VALIDATION OF A CLINICAL RISK SCORE FOR POSTOPERATIVE OUTCOME IN NEWLY DIAGNOSED GLIOBLASTOMA: A REPORT OF THE RANO RESECT GROUP by Karschnia, P, Young, J S, Youssef, G C, Dono, A, Häni, L, Sciortino, T, Bruno, F, Juenger, S T, Teske, N, Dietrich, J, Weller, M, Vogelbaum, M A, van den Bent, M, Beck, J, Thon, N, Gerritsen, J K, Hervey-Jumper, S, Cahill, D P, Chang, S M, Rudà, R, Bello, L, Schnell, O, Esquenazi, Y, Ruge, M I, Grau, S J, Huang, R Y, Wen, P Y, Berger, M S, Molinaro, A M, Tonn, J

“…Abstract BACKGROUND Following resection or biopsy, patients with newly diagnosed glioblastoma frequently enter clinical trials. Nuanced risk assessment is…”
Get full text

JS05.7.A SURGICAL RE-RESECTION FOR RECURRENT GLIOBLASTOMA: PROGNOSTIC EVALUATION USING THE NOVEL RANO CLASSIFICATION FOR EXTENT OF RESECTION FROM THE RANO RESECT GROUP by Karschnia, P, Dono, A, Young, J S, Juenger, S T, Teske, N, Häni, L, Sciortino, T, Mau, C Y, Bruno, F, Nunez, L, Morshed, R A, Haddad, A F, Weller, M, van den Bent, M, Beck, J, Hervey-Jumper, S, Molinaro, A M, Tandon, N, Rudà, R, Vogelbaum, M A, Bello, L, Schnell, O, Grau, S J, Chang, S M, Berger, M S, Esquenazi, Y, Tonn, J

“…Abstract BACKGROUND The value of re-resection in recurrent glioblastoma remains controversial as a randomized trial that specifies intentional incomplete…”
Get full text

JS05.7.A SURGICAL RE-RESECTION FOR RECURRENT GLIOBLASTOMA: PROGNOSTIC EVALUATION USING THE NOVEL RANO CLASSIFICATION FOR EXTENT OF RESECTION FROM THE RANORESECT GROUP by Karschnia, P, Dono, A, Young, J S, Juenger, S T, Teske, N, Häni, L, Sciortino, T, Mau, C Y, Bruno, F, Nunez, L, Morshed, R A, Haddad, A F, Weller, M, van den Bent, M, Beck, J, Hervey-Jumper, S, Molinaro, A M, Tandon, N, Rudà, R, Vogelbaum, M A, Bello, L, Schnell, O, Grau, S J, Chang, S M, Berger, M S, Esquenazi, Y, Tonn, J

Get full text

A nomogram for individualized estimation of survival among patients with brain metastasis by Barnholtz-Sloan, Jill S, Yu, Changhong, Sloan, Andrew E, Vengoechea, Jaime, Wang, Meihua, Dignam, James J, Vogelbaum, Michael A, Sperduto, Paul W, Mehta, Minesh P, Machtay, Mitchell, Kattan, Michael W

“…An estimated 24%-45% of patients with cancer develop brain metastases. Individualized estimation of survival for patients with brain metastasis could be useful…”
Get full text

PL3.3 Second interim and first molecular analysis of the EORTC randomized phase III intergroup CATNON trial on concurrent and adjuvant temozolomide in anaplastic glioma without 1p/19q codeletion by van den Bent, M J, Erridge, S, Vogelbaum, M A, Nowak, A K, Sanson, M, Brandes, A A, Wick, W, Clement, P M, Baurain, J F, Mason, W, Wheeler, H, Weller, M, Aldape, K, Wesseling, P, Kros, J M, Tesileanu, C M S, Golfinopoulos, V, Gorlia, T, Baumert, B G, French, P J

“…Abstract BACKGROUND The 1st interim analysis of the CATNON trial showed benefit from adjuvant (adj) temozolomide (TMZ) on overall survival (OS) but remained…”
Get full text