Search Results - "Vogel, Kristen J"
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Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing
Published in Genetics in medicine (01-08-2016)“…Germ-line testing for panels of cancer genes using next-generation sequencing is becoming more common in clinical care. We report our experience as a clinical…”
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The Evolution of Cancer Risk Assessment in the Era of Next Generation Sequencing
Published in Journal of genetic counseling (01-08-2014)“…Cancer genetics professionals face a new opportunity and challenge in adapting to the availability of cancer genetic testing panels, now available as a result…”
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Cancer Genetic Counseling and Testing in an Era of Rapid Change
Published in Journal of genetic counseling (01-12-2017)“…The impacts of the Association for Molecular Pathology vs. Myriad Supreme Court decision regarding patenting DNA segments and multi-gene testing on cancer…”
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Accuracy of Perceived Breast Cancer Risk in Black and White Women with an Elevated Risk
Published in Ethnicity & disease (21-04-2022)“…Perceived breast cancer risk predicts screening behaviors. However, perceived risk is often inaccurate, notably in Black women, who often underestimate their…”
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Urologists' Current Practices in Screening and Treating Men with a Family History of Prostate Cancer
Published in Urology (Ridgewood, N.J.) (01-01-2017)“…Abstract Objective To assess urologists' knowledge and utilization of family history in order to determine prostate cancer (PC) screening and treatment…”
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Alcohol and Tobacco Lower the Age of Presentation in Sporadic Pancreatic Cancer in a Dose-Dependent Manner: A Multicenter Study
Published in The American journal of gastroenterology (01-11-2012)“…The objective of this study was to examine the association between tobacco and alcohol dose and type and the age of onset of pancreatic adenocarcinoma…”
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Initial clinical validation of Health Heritage, a patient-facing tool for personal and family history collection and cancer risk assessment
Published in Familial cancer (01-04-2016)“…Personal and family health histories remain important independent risk factors for cancer; however they are currently not being well collected or used…”
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Utilization of breast cancer risk prediction models by cancer genetic counselors in clinical practice predominantly in the United States
Published in Journal of genetic counseling (01-12-2021)“…Risk assessment in cancer genetic counseling is essential in identifying individuals at high risk for developing breast cancer to recommend appropriate…”
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BRCA1 and BRCA2 Genetic Testing in Hispanic Patients: Mutation Prevalence and Evaluation of the BRCAPRO Risk Assessment Model
Published in Journal of clinical oncology (10-10-2007)“…The BRCAPRO model, used to predict a family's likelihood of carrying a BRCA1 or BRCA2 mutation, was designed using mutation frequencies of white and Ashkenazi…”
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FDA Approval of PARP Inhibitors and the Impact on Genetic Counseling and Genetic Testing Practices
Published in Journal of genetic counseling (01-02-2018)“…In December 2014, the FDA approved olaparib, a poly(ADP-ribose) polymerase inhibitor (PARPi) for ovarian cancer patients who have failed three or more lines of…”
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Evaluation of laboratory perspectives on hereditary cancer panels
Published in Familial cancer (01-10-2016)“…Genetic counseling and testing for hereditary cancer susceptibility is a rapidly evolving field and partly a result of next-generation sequencing (NGS)…”
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Monoallelic MUTYH pathogenic variants ascertained via multi-gene hereditary cancer panels are not associated with colorectal, endometrial, or breast cancer
Published in Familial cancer (01-10-2022)“…We aimed to determine whether monoallelic MUTYH pathogenic and likely pathogenic variants (PVs) are associated with colorectal, breast, and endometrial cancer…”
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Family Physicians’ Awareness and Knowledge of the Genetic Information Non-Discrimination Act (GINA)
Published in Journal of genetic counseling (01-04-2012)“…Historically, physicians have expressed concern about their patients’ risk of genetic discrimination, which has acted as a barrier to uptake of genetic…”
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Learning to Say No
Published in Journal of genetic counseling (01-04-2012)“…The author reflects on issues of being overworked and professional burnout. Part of a special journal issue focused on 'defining moments' in genetic counselor…”
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Cancer genetic testing panels for inherited cancer susceptibility: the clinical experience of a large adult genetics practice
Published in Familial cancer (01-12-2014)“…Next-generation sequencing genetic testing panels for cancer susceptibility (cancer panels) have recently become clinically available. At present, clinical…”
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Tu1874 Earlier Age of Presentation of Pancreatic Adenocarcinoma in Individuals With Chronic Pancreatitis
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2013)Get full text
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10 rare tumors that warrant a genetics referral
Published in Familial cancer (01-03-2013)“…The number of described cancer susceptibility syndromes continues to grow, as does our knowledge on how to manage these syndromes with the aim of early…”
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Genetic counselors’ perspectives on population‐based screening for BRCA‐related hereditary breast and ovarian cancer and Lynch syndrome
Published in Journal of genetic counseling (01-02-2021)“…Early identification of those with BRCA‐related Hereditary Breast and Ovarian Cancer Syndrome (HBOC) and Lynch syndrome has the potential for early cancer…”
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Using a Family History Intervention to Improve Cancer Risk Perception in a Black Community
Published in Journal of genetic counseling (01-12-2011)“…Few studies examine the use of family history to influence risk perceptions in the African American population. This study examined the influence of a family…”
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Accuracy of the BRCAPRO model among women with bilateral breast cancer
Published in Cancer (15-02-2009)“…BACKGROUND: The likelihood of identifying a BRCA mutation was often calculated using the BRCAPRO model. A previous study suggested that this model may…”
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