Search Results - "Voegele, Catherine"

Beta HPV38 oncoproteins act with a hit-and-run mechanism in ultraviolet radiation-induced skin carcinogenesis in mice by Viarisio, Daniele, Müller-Decker, Karin, Accardi, Rosita, Robitaille, Alexis, Dürst, Matthias, Beer, Katrin, Jansen, Lars, Flechtenmacher, Christa, Bozza, Matthias, Harbottle, Richard, Voegele, Catherine, Ardin, Maude, Zavadil, Jiri, Caldeira, Sandra, Gissmann, Lutz, Tommasino, Massimo

“…Cutaneous beta human papillomavirus (HPV) types are suspected to be involved, together with ultraviolet (UV) radiation, in the development of non-melanoma skin…”
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Elucidating Genomic Characteristics of Lung Cancer Progression from In Situ to Invasive Adenocarcinoma by Vinayanuwattikun, Chanida, Le Calvez-Kelm, Florence, Abedi-Ardekani, Behnoush, Zaridze, David, Mukeria, Anush, Voegele, Catherine, Vallée, Maxime, Purnomosari, Dewajani, Forey, Nathalie, Durand, Geoffroy, Byrnes, Graham, Mckay, James, Brennan, Paul, Scelo, Ghislaine

“…To examine the diversity of somatic alterations and clonal evolution according to aggressiveness of disease, nineteen tumor-blood pairs of ‘formerly…”
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Rare, Evolutionarily Unlikely Missense Substitutions in ATM Confer Increased Risk of Breast Cancer by Tavtigian, Sean V., Oefner, Peter J., Babikyan, Davit, Hartmann, Anne, Healey, Sue, Le Calvez-Kelm, Florence, Lesueur, Fabienne, Byrnes, Graham B., Chuang, Shu-Chun, Forey, Nathalie, Feuchtinger, Corinna, Gioia, Lydie, Hall, Janet, Hashibe, Mia, Herte, Barbara, McKay-Chopin, Sandrine, Thomas, Alun, Vallée, Maxime P., Voegele, Catherine, Webb, Penelope M., Whiteman, David C., Sangrajrang, Suleeporn, Hopper, John L., Southey, Melissa C., Andrulis, Irene L., John, Esther M., Chenevix-Trench, Georgia

“…The susceptibility gene for ataxia telangiectasia, ATM, is also an intermediate-risk breast-cancer-susceptibility gene. However, the spectrum and frequency…”
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Urinary TERT promoter mutations are detectable up to 10 years prior to clinical diagnosis of bladder cancer: Evidence from the Golestan Cohort Study by Hosen, Md Ismail, Sheikh, Mahdi, Zvereva, Maria, Scelo, Ghislaine, Forey, Nathalie, Durand, Geoffroy, Voegele, Catherine, Poustchi, Hossein, Khoshnia, Masoud, Roshandel, Gholamreza, Sotoudeh, Masoud, Nikmanesh, Arash, Etemadi, Arash, Avogbe, Patrice Hodonou, Chopard, Priscilia, Delhomme, Tiffany Myriam, Foll, Matthieu, Manel, Arnaud, Vian, Emmanuel, Weiderpass, Elisabete, Kamangar, Farin, Boffetta, Paolo, Pharaoh, Paul D., Dawsey, Sanford M., Abnet, Christian C., Brennan, Paul, McKay, James, Malekzadeh, Reza, Calvez-Kelm, Florence Le

“…Detecting pre-clinical bladder cancer (BC) using urinary biomarkers may provide a valuable opportunity for screening and management. Telomerase reverse…”
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Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancer by Avogbe, Patrice Hodonou, Manel, Arnaud, Vian, Emmanuel, Durand, Geoffroy, Forey, Nathalie, Voegele, Catherine, Zvereva, Maria, Hosen, Md Ismail, Meziani, Sonia, De Tilly, Berengere, Polo, Gilles, Lole, Olesia, Francois, Pauline, Delhomme, Tiffany Myriam, Carreira, Christine, Monteiro-Reis, Sara, Henrique, Rui, Abedi-Ardekani, Behnoush, Byrnes, Graham, Foll, Matthieu, Weiderpass, Elisabete, McKay, James, Jeronimo, Carmen, Scelo, Ghislaine, Le Calvez-Kelm, Florence

“…Recurrent mutations in the promoter of the telomerase reverse transcriptase (TERT) gene (C228T and C250T) detected in tumours and cells shed into urine of…”
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Hepatitis B virus preS2Δ38–55 variants: A newly identified risk factor for hepatocellular carcinoma by Cohen, Damien, Ghosh, Sumantra, Shimakawa, Yusuke, Ramou, Njie, Garcia, Pierre Simon, Dubois, Anaëlle, Guillot, Clément, Kakwata-Nkor Deluce, Nora, Tilloy, Valentin, Durand, Geoffroy, Voegele, Catherine, Ndow, Gibril, d'Alessandro, Umberto, Brochier-Armanet, Céline, Alain, Sophie, Le Calvez-Kelm, Florence, Hall, Janet, Zoulim, Fabien, Mendy, Maimuna, Thursz, Mark, Lemoine, Maud, Chemin, Isabelle

“…Although HBV is a major cause of death in Africa, its genetic variability has been poorly documented. This study aimed to address whether HBV genotype and…”
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Circulating tumour-derived KRAS mutations in pancreatic cancer cases are predominantly carried by very short fragments of cell-free DNA by Zvereva, Maria, Roberti, Gabriel, Durand, Geoffroy, Voegele, Catherine, Nguyen, Minh Dao, Delhomme, Tiffany M., Chopard, Priscilia, Fabianova, Eleonora, Adamcakova, Zora, Holcatova, Ivana, Foretova, Lenka, Janout, Vladimir, Brennan, Paul, Foll, Matthieu, Byrnes, Graham B., McKay, James D., Scelo, Ghislaine, Le Calvez-Kelm, Florence

“…The DNA released into the bloodstream by malignant tumours· called circulating tumour DNA (ctDNA), is often a small fraction of total cell-free DNA shed…”
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First Molecular Characterization of Chronic Hepatitis B Carriers in Timbuktu, Mali by Lawrence, Philip, Chabane, Mawlouda, Abrouk, Lucie, Thiesson, Adrien, Berthé, Diakaridia, Diarra, Amadou B, Bengaly, Karim, Traoré, Brehima, Kassogué, Djibril, Durand, Geoffroy, Voegele, Catherine, Le Calvez-Kelm, Florence, Steenkeste, Nicolas, Hainaut, Pierre, Kouriba, Bourema, Gormally, Emmanuelle

“…In Mali, hepatocellular carcinoma (HCC) is the third and sixth most common cancer in men and women, respectively. Mali comprises several distinct…”
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Revealing the Molecular Portrait of Triple Negative Breast Tumors in an Understudied Population through Omics Analysis of Formalin-Fixed and Paraffin-Embedded Tissues by Vaca-Paniagua, Felipe, Alvarez-Gomez, Rosa María, Maldonado-Martínez, Hector Aquiles, Pérez-Plasencia, Carlos, Fragoso-Ontiveros, Veronica, Lasa-Gonsebatt, Federico, Herrera, Luis Alonso, Cantú, David, Bargallo-Rocha, Enrique, Mohar, Alejandro, Durand, Geoffroy, Forey, Nathalie, Voegele, Catherine, Vallée, Maxime, Le Calvez-Kelm, Florence, McKay, James, Ardin, Maude, Villar, Stéphanie, Zavadil, Jiri, Olivier, Magali

“…Triple negative breast cancer (TNBC), defined by the lack of expression of the estrogen receptor, progesterone receptor and human epidermal receptor 2, is an…”
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RAD51 and breast cancer susceptibility: no evidence for rare variant association in the Breast Cancer Family Registry study by Le Calvez-Kelm, Florence, Oliver, Javier, Damiola, Francesca, Forey, Nathalie, Robinot, Nivonirina, Durand, Geoffroy, Voegele, Catherine, Vallée, Maxime P, Byrnes, Graham, Registry, Breast Cancer Family, Hopper, John L, Southey, Melissa C, Andrulis, Irene L, John, Esther M, Tavtigian, Sean V, Lesueur, Fabienne

“…Although inherited breast cancer has been associated with germline mutations in genes that are functionally involved in the DNA homologous recombination repair…”
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Epstein - Barr virus transforming protein LMP-1 alters B cells gene expression by promoting accumulation of the oncoprotein ΔNp73α by Accardi, Rosita, Fathallah, Ikbal, Gruffat, Henri, Mariggiò, Giuseppe, Le Calvez-Kelm, Florence, Voegele, Catherine, Bartosch, Birke, Hernandez-Vargas, Hector, McKay, James, Sylla, Bakary S, Manet, Evelyne, Tommasino, Massimo

“…Many studies have proved that oncogenic viruses develop redundant mechanisms to alter the functions of the tumor suppressor p53. Here we show that Epstein-Barr…”
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ABRAXAS (FAM175A) and Breast Cancer Susceptibility: No Evidence of Association in the Breast Cancer Family Registry by Renault, Anne-Laure, Lesueur, Fabienne, Coulombe, Yan, Gobeil, Stéphane, Soucy, Penny, Hamdi, Yosr, Desjardins, Sylvie, Le Calvez-Kelm, Florence, Vallée, Maxime, Voegele, Catherine, Hopper, John L, Andrulis, Irene L, Southey, Melissa C, John, Esther M, Masson, Jean-Yves, Tavtigian, Sean V, Simard, Jacques

“…Approximately half of the familial aggregation of breast cancer remains unexplained. This proportion is less for early-onset disease where familial aggregation…”
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Rare key functional domain missense substitutions in MRE11A, RAD50, and NBNcontribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study by Damiola, Francesca, Pertesi, Maroulio, Oliver, Javier, Le Calvez-Kelm, Florence, Voegele, Catherine, Young, Erin L, Robinot, Nivonirina, Forey, Nathalie, Durand, Geoffroy, Vallñe, Maxime P, Tao, Kayoko, Roane, Terrell C, Williams, Gareth J, Hopper, John L, Southey, Melissa C, Andrulis, Irene L, John, Esther M, Goldgar, David E, Lesueur, Fabienne, Tavtigian, Sean V

“…Abstract Introduction The MRE11A-RAD50-Nibrin (MRN) complex plays several critical roles related to repair of DNA double-strand breaks. Inherited mutations in…”
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Determining the effectiveness of High Resolution Melting analysis for SNP genotyping and mutation scanning at the TP53 locus by Garritano, Sonia, Gemignani, Federica, Voegele, Catherine, Nguyen-Dumont, Tú, Le Calvez-Kelm, Florence, De Silva, Deepika, Lesueur, Fabienne, Landi, Stefano, Tavtigian, Sean V

“…Together single nucleotide substitutions and small insertion/deletion variants are the most common form of sequence variation in the human gene…”
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Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids by Alcala, N., Leblay, N., Gabriel, A. A. G., Mangiante, L., Hervas, D., Giffon, T., Sertier, A. S., Ferrari, A., Derks, J., Ghantous, A., Delhomme, T. M., Chabrier, A., Cuenin, C., Abedi-Ardekani, B., Boland, A., Olaso, R., Meyer, V., Altmuller, J., Le Calvez-Kelm, F., Durand, G., Voegele, C., Boyault, S., Moonen, L., Lemaitre, N., Lorimier, P., Toffart, A. C., Soltermann, A., Clement, J. H., Saenger, J., Field, J. K., Brevet, M., Blanc-Fournier, C., Galateau-Salle, F., Le Stang, N., Russell, P. A., Wright, G., Sozzi, G., Pastorino, U., Lacomme, S., Vignaud, J. M., Hofman, V., Hofman, P., Brustugun, O. T., Lund-Iversen, M., Thomas de Montpreville, V., Muscarella, L. A., Graziano, P., Popper, H., Stojsic, J., Deleuze, J. F., Herceg, Z., Viari, A., Nuernberg, P., Pelosi, G., Dingemans, A. M. C., Milione, M., Roz, L., Brcic, L., Volante, M., Papotti, M. G., Caux, C., Sandoval, J., Hernandez-Vargas, H., Brambilla, E., Speel, E. J. M., Girard, N., Lantuejoul, S., McKay, J. D., Foll, M., Fernandez-Cuesta, L.

“…The worldwide incidence of pulmonary carcinoids is increasing, but little is known about their molecular characteristics. Through machine learning and…”
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Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing by Esposti, Davide Degli, Hernandez-Vargas, Hector, Voegele, Catherine, Fernandez-Jimenez, Nora, Forey, Nathalie, Bancel, Brigitte, Le Calvez-Kelm, Florence, McKay, James, Merle, Philippe, Herceg, Zdenko

“…Functional characterization of long non-coding RNAs (lncRNAs) and their pathological relevance is still a challenging task. Abnormal expression of a few long…”
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Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity by Mangiante, Lise, Alcala, Nicolas, Sexton-Oates, Alexandra, Di Genova, Alex, Gonzalez-Perez, Abel, Khandekar, Azhar, Bergstrom, Erik N., Kim, Jaehee, Liu, Xiran, Blazquez-Encinas, Ricardo, Giacobi, Colin, Le Stang, Nolwenn, Boyault, Sandrine, Cuenin, Cyrille, Tabone-Eglinger, Severine, Damiola, Francesca, Voegele, Catherine, Ardin, Maude, Michallet, Marie-Cecile, Soudade, Lorraine, Delhomme, Tiffany M., Poret, Arnaud, Brevet, Marie, Copin, Marie-Christine, Giusiano-Courcambeck, Sophie, Damotte, Diane, Girard, Cecile, Hofman, Veronique, Hofman, Paul, Mouroux, Jérôme, Cohen, Charlotte, Lacomme, Stephanie, Mazieres, Julien, de Montpreville, Vincent Thomas, Perrin, Corinne, Planchard, Gaetane, Rousseau, Nathalie, Rouquette, Isabelle, Sagan, Christine, Scherpereel, Arnaud, Thivolet, Francoise, Vignaud, Jean-Michel, Jean, Didier, Ilg, Anabelle Gilg Soit, Olaso, Robert, Meyer, Vincent, Boland-Auge, Anne, Deleuze, Jean-Francois, Altmuller, Janine, Nuernberg, Peter, Ibáñez-Costa, Alejandro, Castaño, Justo P., Lantuejoul, Sylvie, Ghantous, Akram, Maussion, Charles, Courtiol, Pierre, Hernandez-Vargas, Hector, Caux, Christophe, Girard, Nicolas, Lopez-Bigas, Nuria, Alexandrov, Ludmil B., Galateau-Salle, Françoise, Foll, Matthieu, Fernandez-Cuesta, Lynnette

“…Malignant pleural mesothelioma (MPM) is an aggressive cancer with rising incidence and challenging clinical management. Through a large series of whole-genome…”
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Druggable growth dependencies and tumor evolution analysis in patient-derived organoids of neuroendocrine neoplasms from multiple body sites by Dayton, Talya L, Alcala, Nicolas, Moonen, Laura, den Hartigh, Lisanne, Geurts, Veerle, Mangiante, Lise, Lap, Lisa, Dost, Antonella F M, Beumer, Joep, Levy, Sonja, van Leeuwaarde, Rachel S, Hackeng, Wenzel M, Samsom, Kris, Voegele, Catherine, Sexton-Oates, Alexandra, Begthel, Harry, Korving, Jeroen, Hillen, Lisa, Brosens, Lodewijk A A, Lantuejoul, Sylvie, Jaksani, Sridevi, Kok, Niels F M, Hartemink, Koen J, Klomp, Houke M, Borel Rinkes, Inne H M, Dingemans, Anne-Marie, Valk, Gerlof D, Vriens, Menno R, Buikhuisen, Wieneke, van den Berg, José, Tesselaar, Margot, Derks, Jules, Speel, Ernst Jan, Foll, Matthieu, Fernández-Cuesta, Lynnette, Clevers, Hans

“…Neuroendocrine neoplasms (NENs) comprise well-differentiated neuroendocrine tumors (NETs) and poorly differentiated neuroendocrine carcinomas (NECs). Treatment…”
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Causal relationships between risk of venous thromboembolism and 18 cancers: a bidirectional Mendelian randomization analysis by Cornish, Naomi, Haycock, Philip, Brenner, Hermann, Figueiredo, Jane C, Galesloot, Tessel E, Grant, Robert C, Johansson, Mattias, Mariosa, Daniela, McKay, James, Pai, Rish, Pellatt, Andrew J, Samadder, N Jewel, Shi, Jianxin, Thibord, Florian, Trégouët, David-Alexandre, Voegele, Catherine, Thirlwell, Chrissie, Mumford, Andrew, Langdon, Ryan

“…Abstract Background People with cancer experience high rates of venous thromboembolism (VTE). Risk of subsequent cancer is also increased in people…”
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Multi-omic dataset of patient-derived tumor organoids of neuroendocrine neoplasms by Alcala, Nicolas, Voegele, Catherine, Mangiante, Lise, Sexton-Oates, Alexandra, Clevers, Hans, Fernandez-Cuesta, Lynnette, Dayton, Talya L, Foll, Matthieu

“…Organoids are 3-dimensional experimental models that summarize the anatomical and functional structure of an organ. Although a promising experimental model for…”
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