Search Results - "Vodermaier, Hartmut C."

APC/C and SCF: Controlling Each Other and the Cell Cycle by Vodermaier, Hartmut C.

“…Regulated protein degradation has emerged as a key recurring theme in multiple aspects of cell-cycle regulation. Importantly, the irreversible nature of…”
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The WD40 Propeller Domain of Cdh1 Functions as a Destruction Box Receptor for APC/C Substrates by Kraft, Claudine, Vodermaier, Hartmut C., Maurer-Stroh, Sebastian, Eisenhaber, Frank, Peters, Jan-Michael

“…Activation of the anaphase-promoting complex/cyclosome (APC/C) by Cdc20 and Cdh1 leads to ubiquitin-dependent degradation of securin and cyclin B and thereby…”
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Human Securin Proteolysis Is Controlled by the Spindle Checkpoint and Reveals When the APC/C Switches from Activation by Cdc20 to Cdh1 by Hagting, Anja, den Elzen, Nicole, Vodermaier, Hartmut C., Waizenegger, Irene C., Peters, Jan-Michael, Pines, Jonathon

“…Progress through mitosis is controlled by the sequential destruction of key regulators including the mitotic cyclins and securin, an inhibitor of anaphase…”
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TPR Subunits of the Anaphase-Promoting Complex Mediate Binding to the Activator Protein CDH1 by Vodermaier, Hartmut C., Gieffers, Christian, Maurer-Stroh, Sebastian, Eisenhaber, Frank, Peters, Jan-Michael

“…Background: Chromosome segregation and mitotic exit depend on activation of the anaphase-promoting complex (APC) by the substrate adaptor proteins CDC20 and…”
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Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression by Gabellini, Davide, Colaluca, Ivan N., Vodermaier, Hartmut C., Biamonti, Giuseppe, Giacca, Mauro, Falaschi, Arturo, Riva, Silvano, Peverali, Fiorenzo A.

“…Hox proteins are transcription factors involved in controlling axial patterning, leukaemias and hereditary malformations. Here, we show that HOXC10 oscillates…”
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Cell cycle: Waiters serving the Destruction machinery by Vodermaier, Hartmut C

“…Targeting regulatory proteins for destruction, and thereby controlling progression through mitosis, is the crucial task for the anaphase-promoting complex…”
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Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex by Wendt, Kerstin S, Vodermaier, Hartmut C, Jacob, Uwe, Gieffers, Christian, Gmachl, Michael, Peters, Jan-Michael, Huber, Robert, Sondermann, Peter

“…The anaphase-promoting complex (APC), or cyclosome, is a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of…”
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APC activators caught by their tails? by Vodermaier, Hartmut C, Peters, Jan-Michael

“…The complexity of the Anaphase-Promoting Complex (APC), the major ubiquitin ligase in mitotic control, has been puzzling investigators ever since its…”
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APC Activators Caught by Their Tails? by Vodermaier, Hartmut C., Peters, Jan-Michael

“…The complexity of the Anaphase-Promoting Complex (APC), the major ubiquitin ligase in mitotic control, has been puzzling investigators ever since its…”
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Conspiracy to disarm APC in interphase by Vodermaier, Hartmut C, Peters, Jan-Michael

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