Search Results - "Vockerodt, M"
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The H3K27me3 demethylase, KDM6B, is induced by Epstein-Barr virus and over-expressed in Hodgkin's Lymphoma
Published in Oncogene (28-04-2011)“…There is now evidence for both increased and decreased activity of the enzymes controlling the methylation of lysine 27 on histone 3 (H3K27) in cancer. One of…”
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S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells
Published in Leukemia (01-01-2018)“…The Hodgkin/Reed–Sternberg cells of classical Hodgkin lymphoma (HL) are characterised by the aberrant activation of multiple signalling pathways. Here we show…”
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Epstein-Barr virus oncoprotein, latent membrane protein-1, reprograms germinal centre B cells towards a Hodgkin's Reed-Sternberg-like phenotype
Published in The Journal of pathology (01-09-2008)“…Although the latent membrane protein-1 (LMP1) of the Epstein-Barr virus (EBV) is believed to be important for the transformation of germinal centre (GC) B…”
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STAT3 is essential for Hodgkin lymphoma cell proliferation and is a target of tyrphostin AG17 which confers sensitization for apoptosis
Published in Leukemia (01-06-2005)“…Classical Hodgkin lymphoma (cHL) is a distinct malignancy of the immune system. Despite the progress made in the understanding of the biology of cHL, the…”
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Expression of Epstein-Barr Virus Nuclear Antigen 1 Is Associated with Enhanced Expression of CD25 in the Hodgkin Cell Line L428
Published in Journal of Virology (01-02-1999)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Epstein–Barr virus latent membrane protein-1 activates CD25 expression in lymphoma cells involving the NFκB pathway
Published in Genes and immunity (01-12-2001)“…Epstein–Barr virus (EBV) is associated with several human malignancies including Burkitt’s lymphoma (BL), Hodgkin’s disease (HD) and nasopharyngeal carcinoma…”
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558 Epstein Barr virus latent membrane protein 1 in Hodgkin lymphoma
Published in European journal of cancer supplements (2010)Get full text
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Transient gene expression and MACS enrichment
Published in Methods in molecular biology (Clifton, N.J.) (2001)Get more information
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Simultaneous analysis of interleukin-10 gene microsatellites and single-nucleotide polymorphisms in parallel with tumour necrosis factor and interferon-gamma short tandem repeats by fluorescence-based polymerase chain reaction
Published in Genes and immunity (01-10-2003)“…Different cytokine genotypes exist in the population, for example, as a result of selective pressure of infectious diseases. It may be that specific cytokine…”
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Immunomagnetic enrichment of CD138 positive cells from weakly infiltrated myeloma patients samples enables the determination of the tumor clone specific IgH rearrangement
Published in Annals of hematology (01-02-2001)“…In multiple myeloma, the polymerase chain reaction (PCR) of the Ig heavy chain with allele-specific oligonucleotide (ASO) primers is a common and…”
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Endogenous MHC Class II Processing of a Viral Nuclear Antigen After Autophagy
Published in Science (American Association for the Advancement of Science) (28-01-2005)“…CD4⁺ T cells classically recognize antigens that are endocytosed and processed in lysosomes for presentation on major histocompatibility complex (MHC) class II…”
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Detection of a Hodgkin/Reed‐Sternberg cell specific immunoglobulin gene rearrangement in the serum DNA of a patient with Hodgkin's disease
Published in British journal of haematology (01-08-1999)“…We analysed multiple serum samples from a patient with mixed cellularity Hodgkin's disease for the Hodgkin/Reed‐Sternberg cell clone‐specific rearranged Ig…”
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Correction: S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells
Published in Leukemia (01-08-2019)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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STAT3 is constitutively activated in Hodgkin cell lines
Published in Blood (01-08-2001)“…Hodgkin disease (HD) represents a malignant lymphoma in which the putative malignant Hodgkin and Reed-Sternberg cells are rare and surrounded by abundant…”
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The Epstein–Barr Virus Latent Membrane Protein 1 Induces Interleukin-10 in Burkitt's Lymphoma Cells but Not in Hodgkin's Cells Involving the p38/SAPK2 Pathway
Published in Virology (New York, N.Y.) (15-02-2001)“…Infection of B cells with Epstein–Barr Virus (EBV) induces interleukin-10 (IL-10) production, which may contribute to transformation. IL-10 can modulate the…”
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Constitutive Expression of c-FLIP in Hodgkin and Reed-Sternberg Cells
Published in The American journal of pathology (01-04-2002)“…Crosslinking of the transmembrane receptor CD95/Fas leads to activation of a signaling cascade resulting in apoptosis. c-FLIP is a recently described protein…”
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The Epstein‐Barr virus oncoprotein latent membrane protein 1 induces expression of the chemokine IP‐10: Importance of mRNA half‐life regulation
Published in International journal of cancer (20-04-2005)“…The latent membrane protein 1 (LMP1) of Epstein‐Barr Virus (EBV) is the main inducer of immuno‐modulatory molecules affecting growth and survival of…”
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Evidence for a pathophysiological role of cysteinyl leukotrienes in classical Hodgkin lymphoma
Published in International journal of cancer (15-11-2008)“…Classical Hodgkin lymphoma (cHL) is characterized histologically by a minority of malignant Hodgkin Reed‐Sternberg cells surrounded by abundant inflammatory…”
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