Search Results - "Vo, Trang T."

INPP4B Is a Tumor Suppressor in the Context of PTEN Deficiency by Vo, Thanh-Trang T, Fruman, David A

“…Enzymes (PI3K and PTEN) controlling cellular levels of 3-phosphorylated phosphoinositides are known as important drivers or suppressors of tumorigenesis in…”
Get more information

mTOR inhibition enhances efficacy of dasatinib in ABL -rearranged Ph-like B-ALL by Gotesman, Moran, Vo, Thanh-Trang T, Herzog, Lee-Or, Tea, Tiffeny, Mallya, Sharmila, Tasian, Sarah K, Konopleva, Marina, Fruman, David A

“…High-risk subtypes of B-cell acute lymphoblastic leukemia (B-ALL) include Philadelphia chromosome-positive (Ph+) B-ALL driven by the oncogene and a more…”
Get full text

Scavenger receptor class F member 2 (SCARF2) as a novel therapeutic target in glioblastoma by Kim, Chaeyeong, Kong, Gyeyeong, Lee, Hyunji, Tran, Quangdon, Vo, Thuy-Trang T., Kwon, So Hee, Park, Jisoo, Kim, Seon-Hwan, Park, Jongsun

“…Scavenger receptor class F member 2 (SCARF2) is expressed by endothelial cells with very large cytoplasmic domains and is the second isotype, also known as…”
Get full text

Statins enhance efficacy of venetoclax in blood cancers by Lee, J Scott, Roberts, Andrew, Juarez, Dennis, Vo, Thanh-Trang T, Bhatt, Shruti, Herzog, Lee-Or, Mallya, Sharmila, Bellin, Richard J, Agarwal, Suresh K, Salem, Ahmed Hamed, Xu, Tu, Jia, Jia, Li, Lingxiao, Hanna, John R, Davids, Matthew S, Fleischman, Angela G, O'Brien, Susan, Lam, Lloyd T, Leverson, Joel D, Letai, Anthony, Schatz, Jonathan H, Fruman, David A

“…Statins have shown promise as anticancer agents in experimental and epidemiologic research. However, any benefit that they provide is likely context-dependent,…”
Get more information

Functional characteristics and research trends of PDE11A in human diseases (Review) by Kong, Gyeyeong, Lee, Hyunji, Vo, Thuy-trang T, Juang, Uijin, Kwon, So Hee, Park, Jisoo, Park, Jongsun, Kim, Seon-Hwan

“…cAMP and cGMP are important secondary messengers involved in cell regulation and metabolism driven by the G protein-coupled receptor. cAMP is converted via…”
Get full text

Influence of extractions on physicochemical characterization and bioactivity of Piper nigrum oils: Study on the non-isothermal decomposition kinetic by Thanh-Tam Huynh, T., Mai, Thanh-Chi, Dang, Chi-Hien, Thuy-Trang Vo, T., Nguyen, Dinh-Truong, Dang, Van-Su, Duy Vu Nguyen, Khang, Tran, Vinh-Thien, Nguyen, Thanh-Danh

“…Black pepper oils have been investigated frequently in the recent years. However, there is a significant variation in physicochemical properties and…”
Get full text

Exploring scavenger receptor class F member 2 and the importance of scavenger receptor family in prediagnostic diseases by Vo, Thuy-Trang T., Kong, Gyeyeong, Kim, Chaeyeong, Juang, Uijin, Gwon, Suhwan, Jung, Woohyeong, Nguyen, Huonggiang, Kim, Seon-Hwan, Park, Jongsun

“…Scavenger Receptor Class F Member 2 ( SCARF2 ), also known as the Type F Scavenger Receptor Family gene, encodes for Scavenger Receptor Expressed by…”
Get full text

AXL is required for hypoxia-mediated hypoxia-inducible factor-1 alpha function in glioblastoma by Vo, Thuy-Trang T., Tran, Quangdon, Hong, Youngeun, Lee, Hyunji, Cho, Hyeonjeong, Kim, Minhee, Park, Sungjin, Kim, Chaeyeong, Bayarmunkh, Choinyam, Boldbaatar, Damdindorj, Kwon, So Hee, Park, Jisoo, Kim, Seon-Hwan, Park, Jongsun

“…Glioblastoma (GBM) is the most aggressive type of central nervous system tumor. Molecular targeting may be important when developing efficient GBM treatment…”
Get full text

mTORC1 Inhibition Induces Resistance to Methotrexate and 6-Mercaptopurine in Ph + and Ph-like B-ALL by Vo, Thanh-Trang T, Lee, J Scott, Nguyen, Duc, Lui, Brandon, Pandori, William, Khaw, Andrew, Mallya, Sharmila, Lu, Mengrou, Müschen, Markus, Konopleva, Marina, Fruman, David A

“…Elevated activity of mTOR is associated with poor prognosis and higher incidence of relapse in B-cell acute lymphoblastic leukemia (B-ALL). Thus, ongoing…”
Get full text

Profiles of Urine Drug Test in Clinical Pain Patients vs Pain Research Study Subjects by Lee, Cheng-ting, Vo, Trang T., Cohen, Abigail S., Ahmed, Shihab, Zhang, Yi, Mao, Jianren, Chen, Lucy

“…Abstract Objective. To examine similarities and differences in urine drug test (UDT) results in clinical pain patients and pain subjects participating in pain…”
Get full text

Abstract 3851: Synergy between statins and BCL-2 inhibitors in blood cancers by Lee, Jong-Hoon S., Vo, Thanh-Trang T., Fruman, David A.

“…BCL-2 is a key pro-survival protein that is highly expressed in many leukemias and lymphomas. ABT-199 (venetoclax) is a small molecule inhibitor of BCL-2 that…”
Get full text

Statins Potentiate the Cytotoxic Effect of ABT-199 in Diffuse Large B Cell Lymphoma by Fruman, David A., Lee, Jong-Hoon Scott, Vo, Thanh-Trang T, Bhatt, Shruti, Schatz, Jonathan H., Letai, Anthony

“…BCL-2 is a key pro-survival protein that is highly expressed in many leukemias and lymphomas. ABT-199 (venetoclax) is a small molecule inhibitor of BCL-2 that…”
Get full text

mTOR Kinase Inhibitors Enhance Efficacy of TKIs in Preclinical Models of Ph-like B-ALL by Gotesman, Moran, Vo, Thanh-Trang T, Mallya, Sharmila, Zhang, Qi, Shi, Ce, Müschen, Markus, Weinstock, David M., Mullighan, Charles, Tasian, Sarah K, Konopleva, Marina, Fruman, David A.

“…Background and Rationale: B-lymphoblastic leukemia (B-ALL) is the most common cancer of childhood. While event-free survival (EFS) exceeds 85% for most…”
Get full text

On discarding low quality produce by Nguyen, D, Vo, T.T

“…Extract: This paper considers a model of optimal culling in which demand is generally nonlinear. We show that the shape of the break-even quality price change…”
Get full text

Measuring Mitochondrial Apoptotic Priming by BH3 Profiling Predicts Induction Outcome for Acute Myeloid Leukemia Patients by Vo, Thanh-Trang T, Stone, Richard, DeAngelo, Daniel J, Frattini, Mark G., Letai, Anthony G.

“…Abstract 239 The mechanistic basis for differential response to induction therapy in AML is poorly understood. Our laboratory has found that primary normal and…”
Get full text