Search Results - "Vlassov, V.V."

Cationic lipid–DNA complexes—lipoplexes—for gene transfer and therapy by Zhdanov, R.I, Podobed, O.V, Vlassov, V.V

“…Cationic lipid-mediated gene transfer and delivery still attract great attention of many gene therapy laboratories. From the point of view of the most…”
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Synthesis and transfection activity of novel galactosylated polycationic lipid by Maslov, M.A., Medvedeva, D.A., Rapoport, D.A., Serikov, R.N., Morozova, N.G., Serebrennikova, G.A., Vlassov, V.V., Zenkova, М.A.

“…In this study, we synthesized a new galactosylated cationic lipid and investigated its biological activity. The structure of lipid combines both spermine…”
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Experimental and theoretical investigation of a capillary pumped loop with a porous element in the condenser by Muraoka, I., Ramos, F.M., Vlassov, V.V.

“…A new CPL design is investigated experimentally and theoretically. In order to create a fixed physical interface between the liquid and the vapor phases inside…”
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Peptide-oligonucleotide conjugates exhibiting pyrimidine-X cleavage specificity efficiently silence miRNA target acting synergistically with RNase H by Patutina, O. A., Bazhenov, M. A., Miroshnichenko, S. K., Mironova, N. L., Pyshnyi, D. V., Vlassov, V. V., Zenkova, M. A.

“…Taking into account the important role of miRNA in carcinogenesis, oncogenic miRNAs are attractive molecules for gene-targeted therapy. Here, we developed a…”
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Nucleic acids in exosomes: Disease markers and intercellular communication molecules by Gusachenko, O. N., Zenkova, M. A., Vlassov, V. V.

“…The term “exosomes” is currently used to describe specific vesicular structures of endosomal origin produced by the majority of eukaryotic cells. These natural…”
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Quantification of Tumor-Specific DNA in Blood of Healthy Women and Breast Cancer Patients by Tamkovich, S.N., Myleiko, V.A., Starikov, A.V., Permyakova, V.I., Vlassov, V.V., Laktionov, P.P.

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Whole-Genome DNA Methylation Analysis of Peripheral Blood Mononuclear Cells in Multiple Sclerosis Patients with Different Disease Courses by Kulakova, O.G., Kabilov, M.R., Danilova, L.V., Popova, E.V., Baturina, O.A., Tsareva, E.Y., Baulina, N.M., Kiselev, I.S., Boyko, A.N., Favorov, A.V., Favorova, O.O., Vlassov, V.V.

“…Multiple sclerosis (MS) is a severe neurodegenerative disease of polygenic etiology affecting the central nervous system. In addition to genetic factors,…”
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Complementary addressed reagents carrying EDTA-Fe(II) groups for directed cleavage of single-stranded nucleic acids by Boutorin, A.S., Vlassov, V.V., Kazakov, S.A., Kutiavin, I.V., Podyminogin, M.A.

“…An octathymidylate derivative carrying an EDTA residue at its 5'-terminus was synthesized. In the presence of Fe 2+, O 2 and dithiotreitol, this derivative…”
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Characteristics of exosomes andmicroparticles discovered in human tears by Grigor'eva, A E, Tamkovich, S N, Eremina, A V, Tupikin, A E, Kabilov, M R, Chernykh, V V, Vlassov, V V, Laktionov, P P, Ryabchikova, E I

“…Exosomes represent a sort of extracellular vesicles, which transfer molecular signals in organism and possess markers of producing cells. Our study was aimed…”
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A method for generating selective DNA probes for the analysis of C-negative regions in human chromosomes by Morozkin, E S, Loseva, E M, Karamysheva, T V, Babenko, V N, Laktionov, P P, Vlassov, V V, Rubtsov, N B

“…Linker-adapter polymerase chain reaction (LA-PCR) is among the most efficient techniques for whole genome DNA amplification. The key stage in LA-PCR is the…”
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Analysis of the operational characteristics and limits of a loop heat pipe with porous element in the condenser by Muraoka, I, Ramos, F.M, Vlassov, V.V

“…This paper analyzes the operational characteristics and limits of a loop heat pipe (LHP) with flat porous elements in the condenser and evaporator. A…”
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Cleavage of RNA by an amphiphilic compound lacking traditional catalytic groups by Kovalev, N.A., Medvedeva, D.A., Zenkova, M.A., Vlassov, V.V.

“… Recently, in experiments with combinatorial libraries of amphiphilic compounds lacking groups, known as catalysts of transesterification reaction, we…”
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Tumoricidal Activity of RNase A and DNase I by Patutina, O A, Mironova, N L, Ryabchikova, E I, Popova, N A, Nikolin, V P, Kaledin, V I, Vlassov, V V, Zenkova, M A

“…In our work the antitumor and antimetastatic activities of RNase A and DNase I were studied using two murine models of pulmonary (Lewis lung carcinoma) and…”
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Cleavage of yeast tRNA Phe with complementary oligonucleotide conjugated to a small ribonuclease mimic by Beloglazova, N.G., Sil’nikov, V.N., Zenkova, M.A., Vlassov, V.V.

“…An oligonucleotide conjugate bearing a chemical construct mimicking the catalytic center of ribonuclease A has been designed and studied. The conjugate…”
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New approaches for cancer treatment: antitumor drugs based on gene-targeted nucleic acids by Patutina, O A, Mironova, N L, Vlassov, V V, Zenkova, M A

“…Currently, the main way to fight cancer is still chemotherapy. This method of treatment is at the height of its capacity, so, setting aside the need for…”
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A Comparison of Target Gene Silencing using Synthetically Modified siRNA and shRNA That Express Recombinant Lentiviral Vectors by Spirin, P V, Baskaran, D, Rubtsov, P M, Zenkova, M A, Vlassov, V V, Chernolovskaya, E L, Prassolov, V S

“…RNA-interference is an effective natural mechanism of post-transcriptional modulation of gene expression. RNA-interference mechanism exist as in high…”
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Cleavage of yeast tRNAPhe with complementary oligonucleotide conjugated to a small ribonuclease mimic by Beloglazova, N.G., Sil'nikov, V.N., Zenkova, M.A., Vlassov, V.V.

“…An oligonucleotide conjugate bearing a chemical construct mimicking the catalytic center of ribonuclease A has been designed and studied. The conjugate…”
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Experimental investigation of natural convective heat transfer from a round plate of complex configuration by Vlassov, V.V., Dreitser, G.A.

“…Experimental results of free convective heat transfer on a round plate with additional elements on the surface at ambient air temperatures are presented. The…”
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Synthesis of alkylating oligonucleotide derivatives containing cholesterol or phenazinium residues at their 3′-terminus and their interaction with DNA within mammalian cells by Boutorin, A.S., Gus'kova, L.V., Ivanova, E.M., Kobetz, N.D., Zarytova, V.F., Ryte, A.S., Yurchenko, L.V., Vlassov, V.V.

“…5′-[ 32P]-labelled alkylating decathymidylate [4-( N-2-chloroethyl) N-methylaminobenzyl]-5′-phosphamide derivatives containing cholesterol or phenazinium…”
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Health Care, Medical Practice, and Medical Ethics in Russia Today by Cassileth, Barrie R, Vlassov, Vasily V, Chapman, Christopher C

“…FOR DECADES Russian leaders sacrificed health care to the financial and human resource needs of military and space efforts. Centralized and government…”
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