Search Results - "Vlasov, G. P."
-
1
In vitro comparison of complementary interactions between synthetic linear/branched oligo/poly- l-lysines and tissue plasminogen activator by means of high-performance monolithic-disk affinity chromatography
Published in Journal of Chromatography A (11-04-2003)“…The recently discovered serine protease called tissue plasminogen activator (t-PA) enables efficient dissolution of blood clots. t-PA works by converting…”
Get full text
Journal Article Conference Proceeding -
2
Molecular properties of lysine dendrimers and their interactions with Aβ-peptides and neuronal cells
Published in Current medicinal chemistry (2013)“…Prevention of amyloidosis by chemical compounds is a potential therapeutic strategy in Alzheimer's, prion and other neurodegenerative diseases. Regularly…”
Get more information
Journal Article -
3
Hyperbranched poly(L-lysine) modified with histidine residues via lysine terminal amino groups: Synthesis and structure
Published in Polymer science. Series A, Chemistry, physics (01-04-2008)“…A method for preparing hyperbranched poly( L -lysine) via the polymerization of N ɛ -carbobenzoxy- L -lysine- N -carboxyanhydride has been developed in order…”
Get full text
Journal Article -
4
Starlike branched and hyperbranched biodegradable polymer systems as DNA carriers
Published in Russian journal of bioorganic chemistry (01-05-2006)“…The information on the synthesis of new biologically compatible and biologically degradable DNA carriers based on starlike polymer conjugates of proteins…”
Get full text
Journal Article -
5
Optimization of transfection properties of DNA-lysine dendrimer complexes
Published in Russian journal of bioorganic chemistry (01-03-2005)“…We studied the possibility of optimizing the DNA transfection properties of carriers based on lysine dendrimers of the third and the fifth generation,…”
Get full text
Journal Article -
6
Peptides Derived from the Third Cytoplasmic Loop of the Serotonin Subtype 1B Receptor Selectively Inhibit Transmission of Serotoninergic Signals via Their Homologous Receptors
Published in Neuroscience and behavioral physiology (01-03-2012)“…A leading role in the interactions of most serotonin-type hormone receptors with heterotrimeric G proteins is played by their third cytoplasmic loops. Studies…”
Get full text
Journal Article -
7
Studies of the molecular mechanisms of action of relaxin on the adenylyl cyclase signaling system using synthetic peptides derived from the LGR7 relaxin receptor
Published in Neuroscience and behavioral physiology (01-09-2007)“…The peptide hormone relaxin produces dose-dependent stimulation of adenylyl cyclase activity in rat tissues (striatum, cardiac and skeletal muscle) and the…”
Get full text
Journal Article -
8
Cationic oligopeptides modified with lipophilic fragments: Use for DNA delivery to cells
Published in Russian journal of bioorganic chemistry (01-01-2005)“…Cationic oligopeptides, including the amphipathic alpha -helical peptides, are applied to the targeted delivery of DNA to eukaryotic cells due to their…”
Get full text
Journal Article -
9
Molecular mass characteristics and hydrodynamic and conformational properties of hyperbranched poly-L-lysines
Published in Polymer science. Series A, Chemistry, physics (01-03-2009)“…Hydrodynamic and conformational properties of hyperbranched poly(amino acids) based on lysine have been studied by static and dynamic light scattering,…”
Get full text
Journal Article -
10
Peptides derived from the third cytoplasmatic loop of serotonin 1B receptor subtype selectively inhibit serotonin signal transduction via a homologous receptor
Published in Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova (01-11-2010)“…The third intracellular loops of hormonal receptors play the main role in the interaction of majority of the serpentine type receptors with heterotrimeric…”
Get more information
Journal Article -
11
Synthesis of polyglutamine conjugates of lysine dendrimers in solution and polymer gel
Published in Polymer science. Series B (01-12-2009)“…The synthesis of polyglutamine conjugates of lysine dendrimers, in which carboxyl groups of polyglutamine chains are linked via one point to the amino groups…”
Get full text
Journal Article -
12
The application of synthetic peptides to characterize the site-directed antiviral humoral immune response in patients with respiratory syncytial viral infection
Published in Klinicheskaia laboratornaia diagnostika (01-07-2012)“…The article deals with the study of characteristics of epitope-specific humoral immune response to respiratory syncytial viral infection depending on nature of…”
Get more information
Journal Article -
13
Hyperbranched polylysines modified with histidine and arginine: The optimization of their DNA compacting and endosomolytic properties
Published in Bioorganicheskaia khimiia (01-07-2009)“…The DNA compacting and transfection properties of hyperbranched polylysines whose N -terminal amino groups were modified with histidine and arginine were…”
Get full text
Journal Article -
14
Hyperbranched polylysines: Mechanism of formation
Published in Polymer science. Series B (01-08-2009)“…To gain insight into the mechanism treating formation of hyperbranched polylysines through the polymerization of N ɛ -carbobenzoxylysine N -carboxyanhydride…”
Get full text
Journal Article -
15
Regulation of Functional Activity of Adenylyl Cyclase Signal System by Synthetic Coil-Forming Peptides in Mouse Fibroblast Culture of Line L (ISM Subline)
Published in Journal of evolutionary biochemistry and physiology (01-03-2002)“…The signal transduction process via adenylyl cyclase system (ACS) requires coordinated functioning of signal proteins--components of ACS. It is suggested that…”
Get full text
Journal Article -
16
Regulatory Action of Synthetic Cationic Peptides Containing Residues of Glutamic Acid on Functional Activity of Components of the Adenylyl Cyclase Signal System
Published in Journal of evolutionary biochemistry and physiology (01-01-2004)“…One of the most important stages of hormonal signal transduction in cells through the hormone-sensitive adenylyl cyclase signal system (ACS) is functional…”
Get full text
Journal Article -
17
Decrease in functional activity of G-proteins hormone-sensitive adenylate cyclase signaling system, during experimental type II diabetes mellitus
Published in Bulletin of experimental biology and medicine (01-12-2006)“…The development of experimental type II diabetes mellitus in rats was accompanied by dysfunction of inhibitory and stimulatory heterotrimeric G-proteins,…”
Get full text
Journal Article -
18
The receptor of serpentine type and the heterotrimeric G protein as targets of action of the polylysine dendrimers
Published in T͡S︡itologii͡a (2008)“…The molecular mechanisms of action of the polycationic peptides--polylysine homo- and heterodendrimers on functional activity of biogenic amines- and peptide…”
Get more information
Journal Article -
19
Lysine dendrimers as vectors for delivery of genetic constructs to eukaryotic cells
Published in Russian journal of genetics (01-06-2007)“…Asymmetrical lysine dendrimers are promising as vectors for delivering gene expression constructs into mammalian cells. The condensing, protective, and…”
Get full text
Journal Article -
20