Search Results - "Vladimír Král"

Recent advances in mixed‐mode chromatographic stationary phases by Sýkora, David, Řezanka, Pavel, Záruba, Kamil, Král, Vladimír

“…Mixed‐mode phases have become very popular in the last decade, and the number of new mixed/multi‐mode sorbents is growing fast. Unlike single‐mode stationary…”
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Identification of intramolecular hydrogen bonds as the origin of malfunctioning of multitopic receptors by Dolenský, Bohumil, Konvalinka, Roman, Jakubek, Milan, Král, Vladimír

“…► Identification of intramolecular hydrogen bonds by NMR and IR. ► 1H NMR temperature coefficients of amides. ► 1H NMR temperature coefficients of atoms, which…”
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Application of cyclodextrins in chiral capillary electrophoresis by Rezanka, Pavel, Navrátilová, Klára, Rezanka, Michal, Král, Vladimír, Sýkora, David

“…CE represents a very powerful separation tool in the area of chiral separations. CD‐mediated chiral CE is a continuously flourishing technique within the frame…”
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Influence of fluorophore and linker length on the localization and trafficking of fluorescent sterol probes by Králová, Jarmila, Jurášek, Michal, Mikšátková, Lucie, Marešová, Anna, Fähnrich, Jan, Cihlářová, Petra, Drašar, Pavel, Bartůněk, Petr, Král, Vladimír

“…Fluorescent sterol probes, comprising a fluorophore connected to a sterol backbone by means of a linker, are promising tools for enabling high-resolution…”
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Strategy for improved therapeutic efficiency of curcumin in the treatment of gastric cancer by Jakubek, Milan, Kejík, Zdeněk, Kaplánek, Robert, Hromádka, Róbert, Šandriková, Viera, Sýkora, David, Antonyová, Veronika, Urban, Marian, Dytrych, Petr, Mikula, Ivan, Martásek, Pavel, Král, Vladimír

“…[Display omitted] •Curcumin is multifunctional agents for the treatment of gastric cancer.•Perspective agents for the improve of chemotherapeutic efficacy.•DDS…”
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Interleukin-6: a molecule with complex biological impact in cancer by Lacina, Lukáš, Brábek, Jan, Král, Vladimír, Kodet, Ondřej, Smetana, Jr, Karel

“…Interleukin-6 is a multifaceted cytokine, usually reported as a pro-inflammatory molecule. However, certain anti-inflammatory activities were also attributed…”
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Separation of oligopeptides, nucleobases, nucleosides and nucleotides using capillary electrophoresis/electrochromatography with sol–gel modified inner capillary wall by Svobodová, Jana, Kofroňová, Olga, Benada, Oldřich, Král, Vladimír, Mikšík, Ivan

“…•Sol–gel stationary phase for open- tubular capillary electrochromatography was developed.•Sol–gel containing porphyrin-brucine conjugate system was…”
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Immobilized strychnine as a new chiral stationary phase for HPLC by Sýkora, David, Vozka, Jiří, Tesařová, Eva, Kalíková, Květa, Havlík, Martin, Matějka, Pavel, Král, Vladimír

“…A new ion‐exchanger type chiral stationary phase for high‐performance liquid chromatography was prepared. The synthetic protocol is based on derivatization of…”
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Influence of surface and finite size effects on the structural and magnetic properties of nanocrystalline lanthanum strontium perovskite manganites by Žvátora, Pavel, Veverka, Miroslav, Veverka, Pavel, Knížek, Karel, Závěta, Karel, Pollert, Emil, Král, Vladimír, Goglio, Graziella, Duguet, Etienne, Kaman, Ondřej

“…Syntheses of nanocrystalline perovskite phases of the general formula La1−xSrxMnO3+δ were carried out employing sol–gel technique followed by thermal treatment…”
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On the Solubility and Lipophilicity of Metallacarborane Pharmacophores by Rak, Jakub, Dejlová, Barbora, Lampová, Hana, Kaplánek, Robert, Matějíček, Pavel, Cígler, Petr, Král, Vladimír

“…Metallacarborane moieties have been identified as promising pharmacophores. The pharmaceutical use of such compounds is, however, complicated by their low…”
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Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders by Králová, Jarmila, Jurášek, Michal, Krčová, Lucie, Dolenský, Bohumil, Novotný, Ivan, Dušek, Michal, Rottnerová, Zdeňka, Kahle, Michal, Drašar, Pavel, Bartůněk, Petr, Král, Vladimír

“…The monitoring of intracellular cholesterol homeostasis and trafficking is of great importance because their imbalance leads to many pathologies. Reliable…”
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Nanoparticles functionalized with phenylboronic acid for the potentiometric detection of saccharides by Shishkanova, Tatiana V., Fitl, Přemysl, Král, Vladimír, Barek, Jiří

“…We have proposed a concept for the analytical application of modified gold nanoparticles in potentiometric sensors. The main idea is to embed modified gold…”
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Potentiometric Electronic Tongue for Taste Assessment of Ibuprofen Based Pharmaceuticals by Shishkanova, Tatiana V., Broncová, Gabriela, Skálová, Annemarie, Prokopec, Vadym, Člupek, Martin, Král, Vladimír

“…The flavor aspect of pharmaceutical formulations is very important in terms of their acceptability for the patient. This work is aimed at using of a novel…”
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Application of gold nanoparticles in separation sciences by SYKORA, David, KASICKA, Václav, MIKSIK, Ivan, REZANKA, Pavel, ZARUBA, Kamil, MATEJKA, Pavel, KRAL, Vladimir

“…The review article is devoted mainly to the description of applications of gold nanoparticles (GNPs) in separation sciences, especially in electromigration and…”
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Design of HIV Protease Inhibitors Based on Inorganic Polyhedral Metallacarboranes by Řezáčová, Pavlína, Pokorná, Jana, Brynda, Jiří, Kožíšek, Milan, Cígler, Petr, Lepšík, Martin, Fanfrlík, Jindřich, Řezáč, Jan, Grantz Šašková, Klára, Sieglová, Irena, Plešek, Jaromír, Šícha, Václav, Grüner, Bohumír, Oberwinkler, Heike, Sedláček’, Juraj, Kräusslich, Hans-Georg, Hobza, Pavel, Král, Vladimír, Konvalinka, Jan

“…HIV protease (HIV PR) is a primary target for anti-HIV drug design. We have previously identified and characterized substituted metallacarboranes as a new…”
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Voltammetric Detection of Catecholamine Metabolites Using Tröger's Base Modified Electrode by Shishkanova, Tatiana V., Broncová, Gabriela, Fitl, Přemysl, Král, Vladimír, Barek, Jiří

“…The advantage of surface modification of voltammetric sensor for determination of catecholamine metabolites such as vanillyl mandelic acid (VMA) and…”
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From Nonpeptide toward Noncarbon Protease Inhibitors: Metallacarboranes as Specific and Potent Inhibitors of HIV Protease by Petr Cígler, Milan Kožíšek, Pavlína Řezáčová, Jíří Brynda, Otwinowski, Zbyszek, Jana Pokorná, Jaromír Plešek, Bohumír Grüner, Lucie Dolečková-Marešová, Martin Máša, Juraj Sedláček, Jochen Bodem, Kräusslich, Hans-Georg, Král, Vladimír, Jan Konvalinka

“…HIV protease (PR) represents a prime target for rational drug design, and protease inhibitors (PI) are powerful antiviral drugs. Most of the current PIs are…”
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Inorganic Polyhedral Metallacarborane Inhibitors of HIV Protease: A New Approach to Overcoming Antiviral Resistance by Kožíšek, Milan, Cígler, Petr, Lepšík, Martin, Fanfrlík, Jindřich, Řezáčová, Pavlína, Brynda, Jiří, Pokorná, Jana, Plešek, Jaromír, Grüner, Bohumír, Grantz Šašková, Klára, Václavíková, Jana, Král, Vladimír, Konvalinka, Jan

“…HIV protease (PR) is a prime target for rational anti-HIV drug design. We have previously identified icosahedral metallacarboranes as a novel class of…”
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Enantioseparation of novel psychoactive chiral amines and their mixture by capillary electrophoresis using cyclodextrins as chiral selectors by Řezanková, Klára, Kohoutová, Radka, Kuchař, Martin, Král, Vladimír, Řezanka, Pavel

“…The prevalence of new psychoactive substances (NPS) has been increasing during the last decade as well as their constant growth of availability across the…”
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Gold and silver nanoparticles for biomolecule immobilization and enzymatic catalysis by Petkova, Galina A, Záruba, Кamil, Žvátora, Pavel, Král, Vladimír

“…In this work, a simple method for alcohol synthesis with high enantiomeric purity was proposed. For this, colloidal gold and silver surface modifications with…”
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