Search Results - "Vlachou, Evi P."

A structural classification of the variant surface glycoproteins of the African trypanosome by Dakovic, Sara, Zeelen, Johan P, Gkeka, Anastasia, Chandra, Monica, van Straaten, Monique, Foti, Konstantina, Zhong, Janet, Vlachou, Evi P, Aresta-Branco, Francisco, Verdi, Joseph P, Papavasiliou, F. Nina, Stebbins, C. Erec

“…Long-term immune evasion by the African trypanosome is achieved through repetitive cycles of surface protein replacement with antigenically distinct versions…”
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A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl by Triller, Gianna, Vlachou, Evi P., Hashemi, Hamidreza, van Straaten, Monique, Zeelen, Johan P., Kelemen, Yosip, Baehr, Carly, Marker, Cheryl L., Ruf, Sandra, Svirina, Anna, Chandra, Monica, Urban, Katharina, Gkeka, Anastasia, Kruse, Sebastian, Baumann, Andreas, Miller, Aubry K., Bartel, Marc, Pravetoni, Marco, Stebbins, C. Erec, Papavasiliou, F. Nina, Verdi, Joseph P.

“…Poorly immunogenic small molecules pose challenges for the production of clinically efficacious vaccines and antibodies. To address this, we generate an…”
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Immunodominant surface epitopes power immune evasion in the African trypanosome by Gkeka, Anastasia, Aresta-Branco, Francisco, Triller, Gianna, Vlachou, Evi P., van Straaten, Monique, Lilic, Mirjana, Olinares, Paul Dominic B., Perez, Kathryn, Chait, Brian T., Blatnik, Renata, Ruppert, Thomas, Verdi, Joseph P., Stebbins, C. Erec, Papavasiliou, F. Nina

“…The African trypanosome survives the immune response of its mammalian host by antigenic variation of its major surface antigen (the variant surface…”
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