Search Results - "Vizoso, Francisco J."
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Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
Published in International journal of molecular sciences (25-08-2017)“…Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to their capacity for local engrafting and differentiating into…”
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Mesenchymal Stem Cell-Based Therapy as an Alternative to the Treatment of Acute Respiratory Distress Syndrome: Current Evidence and Future Perspectives
Published in International journal of molecular sciences (01-08-2021)“…Acute respiratory distress syndrome (ARDS) represents a current challenge for medicine due to its incidence, morbidity and mortality and, also, the absence of…”
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Mesenchymal Stem Cells in Homeostasis and Systemic Diseases: Hypothesis, Evidences, and Therapeutic Opportunities
Published in International journal of molecular sciences (31-07-2019)“…Mesenchymal stem cells (MSCs) are present in all organs and tissues, playing a well-known function in tissue regeneration. However, there is also evidence…”
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Mesenchymal Stem Cells as a Cornerstone in a Galaxy of Intercellular Signals: Basis for a New Era of Medicine
Published in International journal of molecular sciences (30-03-2021)“…Around 40% of the population will suffer at some point in their life a disease involving tissue loss or an inflammatory or autoimmune process that cannot be…”
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Mesenchymal (Stem) Stromal Cells Based as New Therapeutic Alternative in Inflammatory Bowel Disease: Basic Mechanisms, Experimental and Clinical Evidence, and Challenges
Published in International journal of molecular sciences (10-08-2022)“…Inflammatory bowel diseases (IBD) are an example of chronic diseases affecting 40% of the population, which involved tissue damage and an inflammatory process…”
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Mesenchymal Stem Cells and Their Derived Products in Ageing and Diseases
Published in International journal of molecular sciences (26-06-2024)“…Despite the enormous efforts of the pharmaceutical industry in the generation of new drugs (55 new ones last year) [...]…”
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Mesenchymal Stem/Stromal Cells and Their Derivates in Acute Diseases: Emergency in the Post-COVID-19 Times
Published in International journal of molecular sciences (05-08-2021)“…The current coronavirus disease-19 (COVID-19) pandemic has strongly revived the pressing need to incorporate new therapeutic alternatives to deal with medical…”
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Aging and Mesenchymal Stem Cells: Basic Concepts, Challenges and Strategies
Published in Biology (Basel, Switzerland) (18-11-2022)“…Aging and frailty are complex processes implicating multifactorial mechanisms, such as replicative senescence, oxidative stress, mitochondrial dysfunction, or…”
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Expression and prognostic significance of fibronectin and matrix metalloproteases in breast cancer metastasis
Published in Histopathology (01-03-2014)“…Aims Fibronectin (FN) has attracted interest in cancer research, owing to its role in tumour progression. The aims of this study were to investigate the…”
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Evaluation of Matrix Metalloproteases by Artificial Intelligence Techniques in Negative Biopsies as New Diagnostic Strategy in Prostate Cancer
Published in International journal of molecular sciences (01-04-2023)“…Usually, after an abnormal level of serum prostate-specific antigen (PSA) or digital rectal exam, men undergo a prostate needle biopsy. However, the…”
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Inflammation and cancer
Published in World journal of gastrointestinal surgery (27-03-2012)“…There is evidence supporting the hypothesis that inflammation participates in providing conditions that lead to cancer.An unresolved inflammation due to any…”
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MMP1 and MMP11 Expression in Peripheral Blood Mononuclear Cells upon Their Interaction with Breast Cancer Cells and Fibroblasts
Published in International journal of molecular sciences (31-12-2020)“…Tumor-infiltrating immune cells phenotype is associated with tumor progression. However, little is known about the phenotype of the peripheral blood…”
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Importance of the origin of mesenchymal (stem) stromal cells in cancer biology: “alliance” or “war” in intercellular signals
Published in Cell & bioscience (10-06-2021)“…Mesenchymal stem cells (MSCs) play a central role in the intercellular signaling within the tumor microenvironment (TME), exchanging signals with cancer cells…”
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Towards a New Concept of Regenerative Endodontics Based on Mesenchymal Stem Cell-Derived Secretomes Products
Published in Bioengineering (Basel) (20-12-2022)“…The teeth, made up of hard and soft tissues, represent complex functioning structures of the oral cavity, which are frequently affected by processes that cause…”
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Study of TLR3, TLR4 and TLR9 in breast carcinomas and their association with metastasis
Published in BMC cancer (03-12-2010)“…Toll-like receptors (TLRs) have garnered an extraordinary amount of interest in cancer research due to their role in tumor progression. By activating the…”
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Synergistic effect of human uterine cervical mesenchymal stem cell secretome and paclitaxel on triple negative breast cancer
Published in Stem cell research & therapy (25-04-2024)“…Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer and, despite its adverse effects, chemotherapy is the standard systemic…”
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Impact of CD68/(CD3+CD20) ratio at the invasive front of primary tumors on distant metastasis development in breast cancer
Published in PloS one (26-12-2012)“…Tumors are infiltrated by macrophages, T and B-lymphocytes, which may favor tumor development by promoting angiogenesis, growth and invasion. The aim of this…”
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Prognostic significance of inflammatory factors expression by stroma from breast carcinomas
Published in Carcinogenesis (New York) (01-08-2016)“…The aim of this work was to evaluate the expression and clinical relevance of some cytokines in breast carcinomas. An immunohistochemical study using tissue…”
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Relationship between the inflammatory molecular profile of breast carcinomas and distant metastasis development
Published in PloS one (08-11-2012)“…Inflammatory conditions may promote tumor progression and aggressiveness. In previous reports, we found a group of breast cancer tumors characterized by…”
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Tailored Hydrogels as Delivery Platforms for Conditioned Medium from Mesenchymal Stem Cells in a Model of Acute Colitis in Mice
Published in Pharmaceutics (23-07-2021)“…Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is increasingly prevalent and current therapies are not…”
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