Search Results - "Vizeli, Patrick"
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Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2021)“…Growing interest has been seen in using lysergic acid diethylamide (LSD) in psychiatric research and therapy. However, no modern studies have evaluated…”
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2
Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2020)“…Lysergic acid diethylamide (LSD) is a classic psychedelic, 3,4-methylenedioxymethamphetamine (MDMA) is an empathogen, and D-amphetamine is a classic stimulant…”
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3
Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2022)“…Growing interest has been seen in using lysergic acid diethylamide (LSD) and psilocybin in psychiatric research and therapy. However, no modern studies have…”
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4
Genetic influence of CYP2D6 on pharmacokinetics and acute subjective effects of LSD in a pooled analysis
Published in Scientific reports (25-05-2021)“…Lysergic acid diethylamide (LSD) is a classic psychedelic substance that is used recreationally and investigated in psychiatric research. There are no…”
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5
Prediction of MDMA response in healthy humans: a pooled analysis of placebo-controlled studies
Published in Journal of psychopharmacology (Oxford) (01-05-2021)“…Background: 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) is used both recreationally and therapeutically. Little is known about the factors influencing…”
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6
Oxytocin receptor gene variations and socio-emotional effects of MDMA: A pooled analysis of controlled studies in healthy subjects
Published in PloS one (18-06-2018)“…Methylenedioxymethamphetamine (MDMA) increases oxytocin, empathy, and prosociality. Oxytocin plays a critical role in emotion processing and social behavior…”
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MDMA-induced changes in within-network connectivity contradict the specificity of these alterations for the effects of serotonergic hallucinogens
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2021)“…It has been reported that serotonergic hallucinogens like lysergic acid diethylamide (LSD) induce decreases in functional connectivity within various…”
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8
Correction to: Safety pharmacology of acute LSD administration in healthy subjects
Published in Psychopharmacology (01-02-2022)Get full text
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9
Effects of 3,4-Methylenedioxymethamphetamine on Conditioned Fear Extinction and Retention in a Crossover Study in Healthy Subjects
Published in Frontiers in pharmacology (13-07-2022)“…3,4-Methylenedioxymethamphetamine (MDMA) has shown initial promise as an adjunct in psychotherapy to treat posttraumatic stress disorder (PTSD). Its efficacy…”
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10
No Influence of Dopamine System Gene Variations on Acute Effects of MDMA
Published in Frontiers in psychiatry (24-10-2019)“…3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) is a recreational substance also investigated as medication for posttraumatic stress disorder. Dopamine (DA)…”
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11
Pharmacological and non-pharmacological predictors of the LSD experience in healthy participants
Published in Translational psychiatry (04-09-2024)“…The pharmacodynamic effects of lysergic acid diethylamide (LSD) are diverse and different in different individuals. Effects of other psychoactive substances…”
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12
Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects
Published in Frontiers in pharmacology (07-09-2017)“…Lisdexamfetamine is a prodrug of D-amphetamine used for the treatment of attention-deficit/hyperactivity disorder (ADHD). Lisdexamfetamine is thought to have a…”
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13
In vitro and in vivo metabolism of psilocybin's active metabolite psilocin
Published in Frontiers in pharmacology (29-04-2024)“…, psilocybin is rapidly dephosphorylated to psilocin which induces psychedelic effects by interacting with the 5-HT receptor. Psilocin primarily undergoes…”
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14
Comparative Untargeted Metabolomics Analysis of the Psychostimulants 3,4-Methylenedioxy-Methamphetamine (MDMA), Amphetamine, and the Novel Psychoactive Substance Mephedrone after Controlled Drug Administration to Humans
Published in Metabolites (27-07-2020)“…Psychoactive stimulants are a popular drug class which are used recreationally. Over the last decade, large numbers of new psychoactive substances (NPS) have…”
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15
Safety pharmacology of acute MDMA administration in healthy subjects
Published in Journal of psychopharmacology (Oxford) (01-05-2017)“…3,4-Methylenedioxymethamphetamine (MDMA; ecstasy) is being investigated in MDMA-assisted psychotherapy. The present study characterized the safety pharmacology…”
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16
Safety pharmacology of acute LSD administration in healthy subjects
Published in Psychopharmacology (01-06-2022)“…Rationale Lysergic acid diethylamide (LSD) is used in psychiatric and psychological research and investigated as a potential treatment for medical and…”
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17
Pharmacokinetics and subjective effects of a novel oral LSD formulation in healthy subjects
Published in British journal of clinical pharmacology (01-07-2019)“…Aims The aim of the present study was to characterize the pharmacokinetics and exposure–subjective response relationship of a novel oral solution of lysergic…”
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18
Flashback phenomena after administration of LSD and psilocybin in controlled studies with healthy participants
Published in Psychopharmacology (01-06-2022)“…Background LSD and psilocybin are increasingly used in phase I trials and evaluated as therapeutic agents for mental disorders. The phenomenon of reoccurring…”
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MDMA-assisted psychotherapy for PTSD: Growing evidence for memory effects mediating treatment efficacy
Published in Progress in neuro-psychopharmacology & biological psychiatry (10-01-2024)“…The application of MDMA in conjunction with psychotherapy has in recent years seen a resurgence of clinical, scientific, and public interest in the treatment…”
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The effect of lysergic acid diethylamide (LSD) on whole-brain functional and effective connectivity
Published in Neuropsychopharmacology (New York, N.Y.) (01-07-2023)“…Psychedelics have emerged as promising candidate treatments for various psychiatric conditions, and given their clinical potential, there is a need to identify…”
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