Search Results - "Vizcay, Gema"

A Moving Source of Matrix Components Is Essential for De Novo Basement Membrane Formation by Matsubayashi, Yutaka, Louani, Adam, Dragu, Anca, Sánchez-Sánchez, Besaiz J., Serna-Morales, Eduardo, Yolland, Lawrence, Gyoergy, Attila, Vizcay, Gema, Fleck, Roland A., Heddleston, John M., Chew, Teng-Leong, Siekhaus, Daria E., Stramer, Brian M.

“…The basement membrane (BM) is a thin layer of extracellular matrix (ECM) beneath nearly all epithelial cell types that is critical for cellular and tissue…”
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Mechanical modelling quantifies the functional importance of outer tissue layers during root elongation and bending by Dyson, Rosemary J, Vizcay‐Barrena, Gema, Band, Leah R, Fernandes, Anwesha N, French, Andrew P, Fozard, John A, Hodgman, T. Charlie, Kenobi, Kim, Pridmore, Tony P, Stout, Michael, Wells, Darren M, Wilson, Michael H, Bennett, Malcolm J, Jensen, Oliver E

“…Root elongation and bending require the coordinated expansion of multiple cells of different types. These processes are regulated by the action of hormones…”
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Phase Diagram for a Lysyl‐Phosphatidylglycerol Analogue in Biomimetic Mixed Monolayers with Phosphatidylglycerol: Insights into the Tunable Properties of Bacterial Membranes by Wölk, Christian, Youssef, Hala, Guttenberg, Thomas, Marbach, Helene, Vizcay‐Barrena, Gema, Shen, Chen, Brezesinski, Gerald, Harvey, Richard D.

“…Ion pairing between the major phospholipids of the Staphylococcus aureus plasma membrane (phosphatidylglycerol – PG and lysyl‐phosphatidylglycerol – LPG)…”
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Glycocalyx sialic acids regulate Nrf2-mediated signaling by fluid shear stress in human endothelial cells by Psefteli, Paraskevi-Maria, Kitscha, Phoebe, Vizcay, Gema, Fleck, Roland, Chapple, Sarah J., Mann, Giovanni E., Fowler, Mark, Siow, Richard C.

“…Activation of the nuclear factor erythroid 2–related factor 2 (Nrf2) pathway is critical for vascular endothelial redox homeostasis in regions of high,…”
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Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3 by Borghesan, Michela, Fafián-Labora, Juan, Eleftheriadou, Olga, Carpintero-Fernández, Paula, Paez-Ribes, Marta, Vizcay-Barrena, Gema, Swisa, Avital, Kolodkin-Gal, Dror, Ximénez-Embún, Pilar, Lowe, Robert, Martín-Martín, Belen, Peinado, Hector, Muñoz, Javier, Fleck, Roland A., Dor, Yuval, Ben-Porath, Ittai, Vossenkamper, Anna, Muñoz-Espin, Daniel, O’Loghlen, Ana

“…Senescence is a cellular phenotype present in health and disease, characterized by a stable cell-cycle arrest and an inflammatory response called…”
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ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43 by Stoica, Radu, De Vos, Kurt J., Paillusson, Sébastien, Mueller, Sarah, Sancho, Rosa M., Lau, Kwok-Fai, Vizcay-Barrena, Gema, Lin, Wen-Lang, Xu, Ya-Fei, Lewis, Jada, Dickson, Dennis W., Petrucelli, Leonard, Mitchell, Jacqueline C., Shaw, Christopher E., Miller, Christopher C. J.

“…Mitochondria and the endoplasmic reticulum (ER) form tight structural associations and these facilitate a number of cellular functions. However, the mechanisms…”
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Arabidopsis MYB26/MALE STERILE35 Regulates Secondary Thickening in the Endothecium and Is Essential for Anther Dehiscence by Yang, Caiyun, Xu, Zhengyao, Song, Jie, Conner, Katie, Barrena, Gema Vizcay, Wilson, Zoe A.

“…The Arabidopsis thaliana MYB26/MALE STERILE35 (MS35) gene is critical for the development of secondary thickening in the anther endothecium and subsequent…”
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XBP1 mRNA Splicing Triggers an Autophagic Response in Endothelial Cells through BECLIN-1 Transcriptional Activation by Margariti, Andriana, Li, Hongling, Chen, Ting, Martin, Daniel, Vizcay-Barrena, Gema, Alam, Saydul, Karamariti, Eirini, Xiao, Qingzhong, Zampetaki, Anna, Zhang, Zhongyi, Wang, Wen, Jiang, Zhixin, Gao, Chan, Ma, Benyu, Chen, Ye-Guang, Cockerill, Gillian, Hu, Yanhua, Xu, Qingbo, Zeng, Lingfang

“…Sustained activation of X-box-binding protein 1 (XBP1) results in endothelial cell (EC) apoptosis and atherosclerosis development. The present study provides…”
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MALE STERILITY1 Is Required for Tapetal Development and Pollen Wall Biosynthesis by Yang, Caiyun, Vizcay-Barrena, Gema, Conner, Katie, Wilson, Zoe A

“…The Arabidopsis thaliana MALE STERILITY1 (MS1) gene is critical for viable pollen formation and has homology to the PHD-finger class of transcription factors;…”
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A Distance-Dependent Distribution of Presynaptic Boutons Tunes Frequency-Dependent Dendritic Integration by Grillo, Federico W., Neves, Guilherme, Walker, Alison, Vizcay-Barrena, Gema, Fleck, Roland A., Branco, Tiago, Burrone, Juan

“…How presynaptic inputs and neurotransmitter release dynamics are distributed along a dendritic tree is not well established. Here, we show that presynaptic…”
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Rapid Homeostatic Turnover of Embryonic ECM during Tissue Morphogenesis by Matsubayashi, Yutaka, Sánchez-Sánchez, Besaiz Jose, Marcotti, Stefania, Serna-Morales, Eduardo, Dragu, Anca, Díaz-de-la-Loza, María-del-Carmen, Vizcay-Barrena, Gema, Fleck, Roland Alexander, Stramer, Brian Marc

“…The extracellular matrix (ECM) is a polymer network hypothesized to form a stable cellular scaffold. While the ECM can undergo acute remodeling during…”
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De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy by Andrejeva, Gabriela, Gowan, Sharon, Lin, Gigin, Wong Te Fong, Anne-Christine LF, Shamsaei, Elham, Parkes, Harry G., Mui, James, Raynaud, Florence I., Asad, Yasmin, Vizcay-Barrena, Gema, Nikitorowicz-Buniak, Joanna, Valenti, Melanie, Howell, Louise, Fleck, Roland A., Martin, Lesley-Ann, Kirkin, Vladimir, Leach, Martin O., Chung, Yuen-Li

“…Macroautophagy/autophagy can enable cancer cells to withstand cellular stress and maintain bioenergetic homeostasis by sequestering cellular components into…”
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Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration by Baron, Olga, Boudi, Adel, Dias, Catarina, Schilling, Michael, Nölle, Anna, Vizcay-Barrena, Gema, Rattray, Ivan, Jungbluth, Heinz, Scheper, Wiep, Fleck, Roland A., Bates, Gillian P., Fanto, Manolis

“…The terminal stages of neuronal degeneration and death in neurodegenerative diseases remain elusive. Autophagy is an essential catabolic process frequently…”
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Sporophytic control of pollen meiotic progression is mediated by tapetum expression of ABORTED MICROSPORES by Tidy, Alison C, Ferjentsikova, Ivana, Vizcay-Barrena, Gema, Liu, Bing, Yin, Wenzhe, Higgins, James D, Xu, Jie, Zhang, Dabing, Geelen, Danny, Wilson, Zoe A

“…Abstract Pollen development is dependent on the tapetum, a sporophytic anther cell layer surrounding the microspores that functions in pollen wall formation…”
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Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis by Lussignol, Marion, Kopp, Martina, Molloy, Kelly, Vizcay-Barrena, Gema, Fleck, Roland A., Dorner, Marcus, Bell, Kierstin L., Chait, Brian T., Rice, Charles M., Catanese, Maria Teresa

“…Hepatitis C virus (HCV) is a unique enveloped virus that assembles as a hybrid lipoviral particle by tightly interacting with host lipoproteins. As a result,…”
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Interaction of amisulpride with GLUT1 at the blood-brain barrier. Relevance to Alzheimer's disease by Boyanova, Sevda T, Lloyd-Morris, Ethlyn, Corpe, Christopher, Rahman, Khondaker Miraz, Farag, Doaa B, Page, Lee K, Wang, Hao, Fleckney, Alice L, Gatt, Ariana, Troakes, Claire, Vizcay-Barrena, Gema, Fleck, Roland, Reeves, Suzanne J, Thomas, Sarah A

“…Blood-brain barrier (BBB) dysfunction may be involved in the increased sensitivity of Alzheimer's disease (AD) patients to antipsychotics, including…”
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Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB) by Sekhar, Gayathri N, Georgian, Ana R, Sanderson, Lisa, Vizcay-Barrena, Gema, Brown, Rachel C, Muresan, Paula, Fleck, Roland A, Thomas, Sarah A

“…Pentamidine is an effective trypanocidal drug used against stage 1 Human African Trypanosomiasis (HAT). At the blood-brain barrier (BBB), it accumulates inside…”
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Multi-synaptic boutons are a feature of CA1 hippocampal connections in the stratum oriens by Rigby, Mark, Grillo, Federico W., Compans, Benjamin, Neves, Guilherme, Gallinaro, Julia, Nashashibi, Sophie, Horton, Sally, Pereira Machado, Pedro M., Carbajal, Maria Alejandra, Vizcay-Barrena, Gema, Levet, Florian, Sibarita, Jean-Baptiste, Kirkland, Angus, Fleck, Roland A., Clopath, Claudia, Burrone, Juan

“…Excitatory synapses are typically described as single synaptic boutons (SSBs), where one presynaptic bouton contacts a single postsynaptic spine. Using serial…”
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Distance-dependent gradient in NMDAR-driven spine calcium signals along tapering dendrites by Walker, Alison S., Neves, Guilherme, Grillo, Federico, Jackson, Rachel E., Rigby, Mark, O’Donnell, Cian, Lowe, Andrew S., Vizcay-Barrena, Gema, Fleck, Roland A., Burrone, Juan

“…Neurons receive a multitude of synaptic inputs along their dendritic arbor, but how this highly heterogeneous population of synaptic compartments is spatially…”
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A novel class of sulphonamides potently block malaria transmission by targeting a Plasmodium vacuole membrane protein by Yahiya, Sabrina, Saunders, Charlie N, Hassan, Sarah, Straschil, Ursula, Fischer, Oliver J, Rueda-Zubiaurre, Ainoa, Haase, Silvia, Vizcay-Barrena, Gema, Famodimu, Mufuliat Toyin, Jordan, Sarah, Delves, Michael J, Tate, Edward W, Barnard, Anna, Fuchter, Matthew J, Baum, Jake

“…Phenotypic cell-based screens are critical tools for discovering candidate drugs for development, yet identification of the cellular target and mode of action…”
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