Search Results - "Vivian C. Hecht"

Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells by Hosios, Aaron M., Hecht, Vivian C., Danai, Laura V., Johnson, Marc O., Rathmell, Jeffrey C., Steinhauser, Matthew L., Manalis, Scott R., Vander Heiden, Matthew G.

“…Cells must duplicate their mass in order to proliferate. Glucose and glutamine are the major nutrients consumed by proliferating mammalian cells, but the…”
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Characterizing deformability and surface friction of cancer cells by Byun, Sangwon, Son, Sungmin, Amodei, Dario, Cermak, Nathan, Shaw, Josephine, Kang, Joon Ho, Hecht, Vivian C., Winslow, Monte M., Jacks, Tyler, Mallick, Parag, Manalis, Scott R.

“…Metastasis requires the penetration of cancer cells through tight spaces, which is mediated by the physical properties of the cells as well as their…”
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Intracellular water exchange for measuring the dry mass, water mass and changes in chemical composition of living cells by Feijó Delgado, Francisco, Cermak, Nathan, Hecht, Vivian C, Son, Sungmin, Li, Yingzhong, Knudsen, Scott M, Olcum, Selim, Higgins, John M, Chen, Jianzhu, Grover, William H, Manalis, Scott R

“…We present a method for direct non-optical quantification of dry mass, dry density and water mass of single living cells in suspension. Dry mass and dry…”
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Deformability of Tumor Cells versus Blood Cells by Shaw Bagnall, Josephine, Byun, Sangwon, Begum, Shahinoor, Miyamoto, David T., Hecht, Vivian C., Maheswaran, Shyamala, Stott, Shannon L., Toner, Mehmet, Hynes, Richard O., Manalis, Scott R.

“…The potential for circulating tumor cells (CTCs) to elucidate the process of cancer metastasis and inform clinical decision-making has made their isolation of…”
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Characterizing Cellular Biophysical Responses to Stress by Relating Density, Deformability, and Size by Byun, Sangwon, Hecht, Vivian C., Manalis, Scott R.

“…Cellular physical properties are important indicators of specific cell states. Although changes in individual biophysical parameters, such as cell size,…”
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Microfluidic platform for characterizing TCR–pMHC interactions by Stockslager, Max A., Bagnall, Josephine Shaw, Hecht, Vivian C., Hu, Kevin, Aranda-Michel, Edgar, Payer, Kristofor, Kimmerling, Robert J., Manalis, Scott R.

“…The physical characteristics of the T cell receptor (TCR)–peptide-major histocompatibility complex (pMHC) interaction are known to play a central role in…”
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Measuring single cell mass, volume, and density with dual suspended microchannel resonators by Bryan, Andrea K, Hecht, Vivian C, Shen, Wenjiang, Payer, Kristofor, Grover, William H, Manalis, Scott R

“…Cell size, measured as either volume or mass, is a fundamental indicator of cell state. Far more tightly regulated than size is density, the ratio between mass…”
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Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes by Hecht, Vivian C, Sullivan, Lucas B, Kimmerling, Robert J, Kim, Dong-Hwee, Hosios, Aaron M, Stockslager, Max A, Stevens, Mark M, Kang, Joon Ho, Wirtz, Denis, Vander Heiden, Matthew G, Manalis, Scott R

“…Cytokine regulation of lymphocyte growth and proliferation is essential for matching nutrient consumption with cell state. Here, we examine how cellular…”
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Correction: Intracellular Water Exchange for Measuring the Dry Mass, Water Mass and Changes in Chemical Composition of Living Cells by Feijó Delgado, Francisco, Cermak, Nathan, Hecht, Vivian C., Son, Sungmin, Li, Yingzhong, Knudsen, Scott M., Olcum, Selim, Higgins, John M., Chen, Jianzhu, Grover, William H., Manalis, Scott R.

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Abstract A36: Amino acids rather than glucose accounts for the majority of cell mass in rapidly proliferating mammalian cells by Hosios, Aaron M., Hecht, Vivian C., Johnson, Marc, Rathmell, Jeffrey C., Manalis, Scott R., Heiden, Matthew G. Vander

“…Abstract To facilitate growth and division, proliferating cells must duplicate their mass over the cell cycle. Glucose and glutamine are the most consumed…”
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Biophysical changes reduce energetic demand in growth factor–deprived lymphocytes by Hecht, Vivian C., Sullivan, Lucas B., Kimmerling, Robert J., Kim, Dong-Hwee, Hosios, Aaron M., Stockslager, Max A., Stevens, Mark M., Kang, Joon Ho, Wirtz, Denis, Vander Heiden, Matthew G., Manalis, Scott R.

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Correction: Intracellular Water Exchange for Measuring the Dry Mass, Water Mass and Changes in Chemical Composition of Living Cells by Francisco Feijó Delgado, Nathan Cermak, Vivian C. Hecht, Sungmin Son, Yingzhong Li, Scott M. Knudsen, Selim Olcum, John M. Higgins, Jianzhu Chen, William H. Grover, Scott R. Manalis

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