Search Results - "Vivar, Raúl"

Cardiac fibroblast cytokine profiles induced by proinflammatory or profibrotic stimuli promote monocyte recruitment and modulate macrophage M1/M2 balance in vitro by Humeres, Claudio, Vivar, Raúl, Boza, Pia, Muñoz, Claudia, Bolivar, Samir, Anfossi, Renatto, Osorio, Jose Miguel, Olivares-Silva, Francisco, García, Lorena, Díaz-Araya, Guillermo

“…Abstract Macrophage polarization plays an essential role in cardiac remodeling after injury, evolving from an initial accumulation of proinflammatory M1…”
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Communication Between Cardiomyocytes and Fibroblasts During Cardiac Ischemia/Reperfusion and Remodeling: Roles of TGF-β, CTGF, the Renin Angiotensin Axis, and Non-coding RNA Molecules by Flores-Vergara, Raúl, Olmedo, Ivonne, Aránguiz, Pablo, Riquelme, Jaime Andrés, Vivar, Raúl, Pedrozo, Zully

“…Communication between cells is a foundational concept for understanding the physiology and pathology of biological systems. Paracrine/autocrine signaling,…”
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IFN-β Plays Both Pro- and Anti-inflammatory Roles in the Rat Cardiac Fibroblast Through Differential STAT Protein Activation by Bolívar, Samir, Anfossi, Renatto, Humeres, Claudio, Vivar, Raúl, Boza, Pía, Muñoz, Claudia, Pardo-Jimenez, Viviana, Olivares-Silva, Francisco, Díaz-Araya, Guillermo

“…Cardiac fibroblasts (CFs) contribute to theinflammatory response to tissue damage, secreting both pro- and anti-inflammatory cytokines and chemokines…”
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Antimigratory Effect of Lipophilic Cations Derived from Gallic and Gentisic Acid and Synergistic Effect with 5-Fluorouracil on Metastatic Colorectal Cancer Cells: A New Synthesis Route by Suárez-Rozas, Cristian, Jara, José Antonio, Cortés, Gonzalo, Rojas, Diego, Araya-Valdés, Gabriel, Molina-Berrios, Alfredo, González-Herrera, Fabiola, Fuentes-Retamal, Sebastián, Aránguiz-Urroz, Pablo, Campodónico, Paola Rossana, Maya, Juan Diego, Vivar, Raúl, Catalán, Mabel

“…Colorectal cancer (CRC) is the third leading cause of cancer deaths in the world. Standard drugs currently used for the treatment of advanced CRC-such as…”
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Statins change the cytokine profile in Trypanosoma cruzi -infected U937 macrophages and murine cardiac tissue through Rho-associated kinases inhibition by González-Herrera, Fabiola, Clayton, Natasha S, Guzmán-Rivera, Daniela, Carrillo, Ileana, Castillo, Christian, Catalán, Mabel, Anfossi, Renatto, Quintero-Pertuz, Helena, Quilaqueo, María Elena, Olea-Azar, Claudio, Rivera-Meza, Mario, Kemmerling, Ulrike, Ridley, Anne J, Vivar, Raúl, Maya, Juan Diego

“…Chronic Chagasic cardiomyopathy (CCC), caused by the protozoan Trypanosoma cruzi, is the most severe manifestation of Chagas disease.CCC is characterized by…”
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Elastin degradation products in acute lung injury induced by gastric contents aspiration by Ayala, Pedro, Vivar, Raúl, Montalva, Rebeca, Olmos, Pablo, Meneses, Manuel, Borzone, Gisella R

“…Gastric contents aspiration is a high-risk condition for acute lung injury (ALI). Consequences range from subclinical pneumonitis to respiratory failure,…”
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Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol by Ayala, Pedro, Montenegro, José, Vivar, Raúl, Letelier, Alan, Urroz, Pablo Aránguiz, Copaja, Miguel, Pivet, Deisy, Humeres, Claudio, Troncoso, Rodrigo, Vicencio, José Miguel, Lavandero, Sergio, Díaz-Araya, Guillermo

“…Increasing evidence indicates that endoplasmic reticulum (ER) stress is involved in various diseases. In the human heart, ischemia/reperfusion has been…”
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Interferon-β decreases LPS-induced neutrophil recruitment to cardiac fibroblasts by Anfossi, Renatto, Vivar, Raúl, Ayala, Pedro, González-Herrera, Fabiola, Espinoza-Pérez, Claudio, Osorio, José Miguel, Román-Torres, Mauricio, Bolívar, Samir, Díaz-Araya, Guillermo

“…Introduction: Cardiac fibroblasts (CF) are crucial cells in damaged heart tissues, expressing TLR4, IFN-receptor and responding to lipopolysaccharide (LPS) and…”
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TGF-β1 prevents simulated ischemia/reperfusion-induced cardiac fibroblast apoptosis by activation of both canonical and non-canonical signaling pathways by Vivar, Raúl, Humeres, Claudio, Ayala, Pedro, Olmedo, Ivonne, Catalán, Mabel, García, Lorena, Lavandero, Sergio, Díaz-Araya, Guillermo

“…Ischemia/reperfusion injury is a major cause of myocardial death. In the heart, cardiac fibroblasts play a critical role in healing post myocardial infarction…”
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Acute lung injury by gastric fluid instillation: activation of myofibroblast apoptosis during injury resolution by Ayala, Pedro, Torres, Jorge, Vivar, Raúl, Meneses, Manuel, Olmos, Pablo, San Martin, Tamara, Borzone, Gisella R

“…Gastric contents aspiration in humans has variable consequences depending on the volume of aspirate, ranging from subclinical pneumonitis to respiratory…”
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EPAC expression and function in cardiac fibroblasts and myofibroblasts by Olmedo, Ivonne, Muñoz, Claudia, Guzmán, Nancy, Catalán, Mabel, Vivar, Raúl, Ayala, Pedro, Humeres, Claudio, Aránguiz, Pablo, García, Lorena, Velarde, Victoria, Díaz-Araya, Guillermo

“…In the heart, cardiac fibroblasts (CF) and cardiac myofibroblasts (CMF) are the main cells responsible for wound healing after cardiac insult. Exchange protein…”
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Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts by Copaja, Miguel, Venegas, Daniel, Aránguiz, Pablo, Canales, Jimena, Vivar, Raúl, Catalán, Mabel, Olmedo, Ivonne, Rodríguez, Andrea E., Chiong, Mario, Leyton, Lisette, Lavandero, Sergio, Díaz-Araya, Guillermo

“…Several clinical trials have shown the beneficial effects of statins in the prevention of coronary heart disease. Additionally, statins promote apoptosis in…”
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FoxO1 mediates TGF-beta1-dependent cardiac myofibroblast differentiation by Vivar, Raúl, Humeres, Claudio, Muñoz, Claudia, Boza, Pía, Bolivar, Samir, Tapia, Felipe, Lavandero, Sergio, Chiong, Mario, Diaz-Araya, Guillermo

“…Cardiac fibroblast differentiation to myofibroblast is a crucial process in the development of cardiac fibrosis and is tightly dependent on transforming growth…”
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Resolvin-D1 attenuation of angiotensin II-induced cardiac inflammation in mice is associated with prevention of cardiac remodeling and hypertension by Olivares-Silva, Francisco, De Gregorio, Nicole, Espitia-Corredor, Jenaro, Espinoza, Claudio, Vivar, Raúl, Silva, David, Osorio, José Miguel, Lavandero, Sergio, Peiró, Concepción, Sánchez-Ferrer, Carlos, Díaz-Araya, Guillermo

“…Despite the broad pharmacological arsenal to treat hypertension, chronic patients may develop irreversible cardiac remodeling and fibrosis. Angiotensin II, the…”
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FoxO1 is required for high glucose-dependent cardiac fibroblasts into myofibroblast phenoconversion by Vivar, Raúl, Anfossi, Renatto, Humeres, Claudio, Catalán, Mabel, Reyes, Christopher, Cárdenas, Simone, Contreras, Alejandra, Aránguiz, Pablo, González, Fabiola, Diaz-Araya, Guillermo

“…In the normal heart, cardiac fibroblasts (CFs) maintain extracellular matrix (ECM) homeostasis, whereas in pathological conditions, such as diabetes mellitus…”
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Lipoxin A4 prevents high glucose-induced inflammatory response in cardiac fibroblast through FOXO1 inhibition by González-Herrera, Fabiola, Anfossi, Renatto, Catalán, Mabel, Gutiérrez-Figueroa, Renata, Maya, Juan Diego, Díaz-Araya, Guillermo, Vivar, Raúl

“…Cardiac cells respond to various pathophysiological stimuli, synthesizing inflammatory molecules that allow tissue repair and proper functioning of the heart;…”
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Resolvin D1 and E1 promote resolution of inflammation in rat cardiac fibroblast in vitro by Salas-Hernández, Aimeé, Espinoza-Pérez, Claudio, Vivar, Raúl, Espitia-Corredor, Jenaro, Lillo, José, Parra-Flores, Pablo, Sánchez-Ferrer, Carlos F., Peiró, Concepción, Díaz-Araya, Guillermo

“…Cardiac fibroblasts (CFs) have a key role in the inflammatory response after cardiac injury and are necessary for wound healing. Resolvins are potent agonists…”
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Gallic acid triphenylphosphonium derivatives TPP+-C10 and TPP+-C12 inhibit mitochondrial function in Candida albicans exerting antifungal and antibiofilm effects by Valderrama, Victoria, Sánchez, Paula, Delso, Macarena, Díaz-Dosque, Mario, Escobar, Alejandro, Budini, Mauricio, Catalán, Mabel, Vivar, Raúl, López-Muñoz, Rodrigo, Jara, José A, Molina-Berríos, Alfredo

“…To evaluate the antifungal and antibiofilm activity of gallic acid derivatives TPP+-C10 and TPP+-C12 and their effects on mitochondrial function on two Candida…”
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Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression by Olivares-Silva, Francisco, Landaeta, Rodolfo, Aránguiz, Pablo, Bolivar, Samir, Humeres, Claudio, Anfossi, Renatto, Vivar, Raúl, Boza, Pía, Muñoz, Claudia, Pardo-Jiménez, Viviana, Peiró, Concepción, Sánchez-Ferrer, Carlos F., Díaz-Araya, Guillermo

“…Cardiac fibroblasts (CF) act as sentinel cells responding to chemokines, cytokines and growth factors released in cardiac tissue in cardiac injury events, such…”
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Angiotensin II Triggers NLRP3 Inflammasome Activation by a Ca2+ Signaling-Dependent Pathway in Rat Cardiac Fibroblast Ang-II by a Ca2+-Dependent Mechanism Triggers NLRP3 Inflammasome in CF by Espitia-Corredor, Jenaro Antonio, Boza, Pía, Espinoza-Pérez, Claudio, Lillo, José Miguel, Rimassa-Taré, Constanza, Machuca, Víctor, Osorio-Sandoval, José Miguel, Vivar, Raúl, Bolivar, Samir, Pardo-Jiménez, Viviana, Sánchez-Ferrer, Carlos Félix, Peiró, Concepción, Díaz-Araya, Guillermo

“…Angiotensin II (Ang-II) is a widely studied hypertensive, profibrotic, and pro-inflammatory peptide. In the heart, cardiac fibroblasts (CF) express type 1…”
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