Search Results - "Vivar, N."

Association of female sex and positive rheumatoid factor with low serum infliximab and anti-drug antibodies, related to treatment failure in early rheumatoid arthritis: results from the SWEFOT trial population by Hambardzumyan, K, Hermanrud, C, Marits, P, Vivar, N, Ernestam, S, Wallman, JK, van Vollenhoven, RF, Fogdell-Hahn, A, Saevarsdottir, S

“…Objective: Infliximab-treated patients with rheumatoid arthritis (RA) may respond insufficiently due to low serum infliximab (sIFX) levels, caused by anti-drug…”
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The role of IL‐1β in reduced IL‐7 production by stromal and epithelial cells: a model for impaired T‐cell numbers in the gut during HIV‐1 infection by Thang, P. H., Ruffin, N., Brodin, D., Rethi, B., Cam, P. D., Hien, N. T., Lopalco, L., Vivar, N., Chiodi, F.

“…  Thang PH, Ruffin N, Brodin D, Rethi B, Cam PD, Hien NT, Lopalco L, Vivar N, Chiodi F (Karolinska Institutet, Stockholm, Sweden; National Institute of…”
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Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss by Krishnamurthy, Akilan, Joshua, Vijay, Haj Hensvold, Aase, Jin, Tao, Sun, Meng, Vivar, Nancy, Ytterberg, A Jimmy, Engström, Marianne, Fernandes-Cerqueira, Cátia, Amara, Khaled, Magnusson, Malin, Wigerblad, Gustaf, Kato, Jungo, Jiménez-Andrade, Juan Miguel, Tyson, Kerry, Rapecki, Stephen, Lundberg, Karin, Catrina, Sergiu-Bogdan, Jakobsson, Per-Johan, Svensson, Camilla, Malmström, Vivianne, Klareskog, Lars, Wähämaa, Heidi, Catrina, Anca I

“…Rheumatoid arthritis (RA)-specific anti-citrullinated protein/peptide antibodies (ACPAs) appear before disease onset and are associated with bone destruction…”
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Dendritic cell reprogramming by endogenously produced lactic acid by Nasi, Aikaterini, Fekete, Tünde, Krishnamurthy, Akilan, Snowden, Stuart, Rajnavölgyi, Eva, Catrina, Anca I, Wheelock, Craig E, Vivar, Nancy, Rethi, Bence

“…The demand for controlling T cell responses via dendritic cell (DC) vaccines initiated a quest for reliable and feasible DC modulatory strategies that would…”
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Early prediction of clinical response to anti-TNF treatment using multi-omics and machine learning in rheumatoid arthritis by Yoosuf, Niyaz, Maciejewski, Mateusz, Ziemek, Daniel, Jelinsky, Scott A, Folkersen, Lasse, Müller, Malin, Sahlström, Peter, Vivar, Nancy, Catrina, Anca, Berg, Louise, Klareskog, Lars, Padyukov, Leonid, Brynedal, Boel

“…Abstract Objectives Advances in immunotherapy by blocking TNF have remarkably improved treatment outcomes for Rheumatoid arthritis (RA) patients. Although…”
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Identification of early risk factors for anti-citrullinated-protein-antibody positive rheumatoid arthritis-a prospective cohort study by Cîrciumaru, Alexandra, Kisten, Yogan, Hansson, Monika, Mathsson-Alm, Linda, Joshua, Vijay, Wähämaa, Heidi, Haarhaus, Malena Loberg, Lindqvist, Joakim, Padyukov, Leonid, Catrina, Sergiu-Bogdan, Fei, Guozhong, Vivar, Nancy, Rezaei, Hamed, Af Klint, Erik, Antovic, Aleksandra, Réthi, Bence, Catrina, Anca I, Hensvold, Aase

“…Individuals positive for anti-cyclic-peptide-antibodies (anti-CCP) and musculoskeletal complaints (MSK-C) are at risk for developing rheumatoid arthritis (RA)…”
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The effects of taxol, a potent platelet antiaggregant, may be due to its microtubular stabilization activity by Canizares, N. Vivar, M. Herdoiza, C.

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Advances in the treatment of rheumatoid arthritis by Vivar, Nancy, Van Vollenhoven, Ronald F

“…The intense pursuit of novel therapies in rheumatoid arthritis has provided physicians with an assorted set of biologic drugs to treat patients with moderate…”
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Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study by Folkersen, Lasse, Brynedal, Boel, Diaz-Gallo, Lina Marcela, Ramsköld, Daniel, Shchetynsky, Klementy, Westerlind, Helga, Sundström, Yvonne, Schepis, Danika, Hensvold, Aase, Vivar, Nancy, Eloranta, Maija-Leena, Rönnblom, Lars, Brunak, Søren, Malmström, Vivianne, Catrina, Anca, Moerch, Ulrik Gw, Klareskog, Lars, Padyukov, Leonid, Berg, Louise

“…In rheumatoid arthritis (RA) several recent efforts have sought to discover means of predicting which patients would benefit from treatment. However, results…”
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Infliximab Versus Conventional Combination Treatment and Seven‐Year Work Loss in Early Rheumatoid Arthritis: Results of a Randomized Swedish Trial by Eriksson, Jonas K., Wallman, Johan K., Miller, Heather, Petersson, Ingemar F., Ernestam, Sofia, Vivar, Nancy, van Vollenhoven, Ronald F., Neovius, Martin

“…Objective To compare long‐term work loss in methotrexate‐refractory early rheumatoid arthritis (RA) patients randomized to the addition of infliximab or…”
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Presence of Ultrasound Imaging Biomarkers Are Good Predictors of Arthritis Development in a Population at Risk for Rheumatoid Arthritis by Kisten, Y, Circiumaru, A, Loberg-Haarhaus, M, Vivar, N, Antovic, A, Rezaei, H, Af Klint, E, Hensvold, A, Catrina, A

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Survival and Proliferation of CD28⁻ T Cells During HIV-1 Infection Relate to the Amplitude of Viral Replication by Vivar, Nancy, Ruffin, Nicolas, Sammicheli, Stefano, Hejdeman, Bo, Rethi, Bence, Chiodi, Francesca

“…Background. CD28⁻ T lymphocytes progressively increase during aging, autoimmunity, and HIV-1 infection. Expansion of these cells stands in contrast with their…”
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Role of the microtubular system in platelet aggregation by Cañizares, C, Vivar, N, Herdoiza, M

“…1. Four structural systems are involved in the process of platelet activation that leads to aggregation: 1) the membrane system, i.e., the cytoplasmic…”
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IL-7 modulates B cells survival and activation by inducing BAFF and CD70 expression in T cells by Sammicheli, Stefano, Ruffin, Nicolas, Lantto, Rebecka, Vivar, Nancy, Chiodi, Francesca, Rethi, Bence

“…Abstract Interleukin-7 (IL-7) promotes the maintenance and activation of peripheral T cells, whereas it does not act directly on mature B cells due to the lack…”
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Development of Ultrasound Detectable Arthritis Among ACPA Positive Subjects with Musculoskeletal Symptoms: The Risk RA Prospective Study by Hensvold, A, Kisten, Y, Circiumaru, A, Hansson, M, Sun, M, Fei, GZ, Vivar, N, af Klint, E, Rezaei, H, Klareskog, L, Antovic, A, Catrina, A

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Limited efficiency of endogenous interleukin-7 levels in T cell reconstitution during HIV-1 infection : will exogenous interleukin-7 therapy work? by RETHI, Bence, VIVAR, Nancy, SAMMICHELI, Stefano, CHIODI, Francesca

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Constraints for monocyte‐derived dendritic cell functions under inflammatory conditions by Fekete, Tünde, Szabo, Attila, Beltrame, Luca, Vivar, Nancy, Pivarcsi, Andor, Lanyi, Arpad, Cavalieri, Duccio, Rajnavölgyi, Eva, Rethi, Bence

“…The activation of TLRs expressed by macrophages or DCs, in the long run, leads to persistently impaired functionality. TLR signals activate a wide range of…”
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IL-7 promotes CD95-induced apoptosis in B cells via the IFN-γ/STAT1 pathway by Sammicheli, Stefano, Dang, Vu Phuong Linh, Ruffin, Nicolas, Pham, Hong Thang, Lantto, Rebecka, Vivar, Nancy, Chiodi, Francesca, Rethi, Bence

“…Interleukin-7 (IL-7) concentrations are increased in the blood of CD4+ T cell depleted individuals, including HIV-1 infected patients. High IL-7 levels might…”
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Antibody Mediated Immunity Drives Response to Methotrexate Treatment in Rheumatoid Arthritis Patients by Brynedal, B, Westerlind, H, Folkersen, L, Padyukov, L, Vivar, N, Catrina, AI, Klareskog, L, Berg, L

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Potential Role for IL-7 in Fas-Mediated T Cell Apoptosis During HIV Infection by Fluur, Caroline, De Milito, Angelo, Fry, Terry J, Vivar, Nancy, Eidsmo, Liv, Atlas, Ann, Federici, Cristina, Matarrese, Paola, Logozzi, Mariantonia, Rajnavolgyi, Eva, Mackall, Crystal L, Fais, Stefano, Chiodi, Francesca, Rethi, Bence

“…IL-7 promotes survival of resting T lymphocytes and induces T cell proliferation in lymphopenic conditions. As elevated IL-7 levels occur in HIV-infected…”
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