Search Results - "Viturino da Silva, José Wellithom"
-
1
Metronidazole thermogel improves retention and decreases permeation through the skin
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2017)“…Metronidazole (MTZ) is widely used as the standard antibiotic for the treatment of rosacea and, more recently, is being used off label in Brazilian hospitals…”
Get full text
Journal Article -
2
Dried Blood Spot Technique-Based Liquid Chromatography-Tandem Mass Spectrometry Method as a Simple Alternative for Benznidazole Pharmacokinetic Assessment
Published in Antimicrobial agents and chemotherapy (01-12-2018)“…Chagas disease (CD) is recognized as one of the major neglected global tropical diseases. Benznidazole (BNZ) is the drug of choice for the treatment of adults,…”
Get full text
Journal Article -
3
Pesticide dermal absorption: Case study x in vitro study
Published in Environmental toxicology and pharmacology (01-04-2020)“…[Display omitted] •In developing countries the use of correct personal protective equipment its use falls short of safe use.•A discussion with the regulatory…”
Get full text
Journal Article -
4
A validated method for simultaneous quantification of four antiretrovirals in dried blood spot and plasma using LC-MS/MS: Application to efavirenz therapeutic drug monitoring in pregnant patients
Published in Clinical biochemistry (01-05-2024)“…•Simultaneous determination of drugs involved in anti-HIV treatment in pregnant women.•DBS represent an alternative sampling method for antiretrovirals TDM…”
Get full text
Journal Article -
5
Development of the stability-indicating method, structural elucidation of new photodegradation products from terconazole by LC-MS TOF, and in vitro toxicity
Published in Journal of pharmaceutical and biomedical analysis (15-07-2022)“…Terconazole (TCZ) was the first triazole antifungal drug launched in the market and has been used in the treatment of vulvovaginal candidiasis. It is also…”
Get full text
Journal Article -
6
Development and validation of a stability‐indicating method, structural elucidation of new degradation products from misoprostol by LC–MS time‐of‐flight, and an ex vivo study of vaginal permeation
Published in Biomedical chromatography (01-08-2024)“…Misoprostol (MSP) is commonly prescribed in obstetrics and gynecology clinical practice for labor induction, cervical ripening, first‐trimester pregnancy…”
Get full text
Journal Article -
7
Structural design, synthesis, and anti-Trypanosomatidae profile of new Pyridyl-thiazolidinones
Published in European journal of medicinal chemistry (05-06-2023)“…The present work reports the synthesis of a novel series of pyridine-thiazolidinones with anti-Trypanosoma cruzi and leishmanicidal activities (compounds…”
Get full text
Journal Article -
8
USO TÓPICO DO CIDOFOVIR PARA TRATAMENTO DAS LESÕES ASSOCIADAS AO PAPILLOMAVÍRUS HUMANO: REVISÃO DA LITERATURA
Published in Infarma (03-04-2017)“…As verrugas genitais são lesões epiteliais induzidas pelo Papillomavirus Humano (HPV). Atualmente, as técnicas utilizadas para tratamento dessas lesões são…”
Get full text
Magazine Article -
9
INFLUÊNCIA DO GÊNERO EM ESTUDOS DE BIOEQUIVALÊNCIA DE MEDICAMENTOS
Published in Infarma (03-04-2017)“…As diferenças anatômicas e fisiológicas entre os gêneros masculino e feminino podem modificar o processo farmacocinético de um fármaco e assim, interferir em…”
Get full text
Magazine Article -
10
Influência do gênero em estudos de bioequivalência de medicamentos
Published in Infarma (01-01-2017)“…As diferenças anatômicas e fisiológicas entre os gêneros masculino e feminino podem modificar o processo farmacocinético de um fármaco e assim, interferir em…”
Get full text
Magazine Article