Search Results - "Vittorio, L"

Exclusive determinations of |Vcb| and R(D∗) through unitarity by Martinelli, G., Simula, S., Vittorio, L.

“…In this work we apply the Dispersive Matrix (DM) method of Di Carlo et al. (Phys Rev D 104:054502, 2021) and Martinelli et al. (Phys Rev D 105:034503, 2022) to…”
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Updates on the determination of |Vcb|,R(D∗) and |Vub|/|Vcb by Martinelli, G., Simula, S., Vittorio, L.

“…We present an updated determination of the values of | V cb | , R ( D ∗ ) and | V ub | / | V cb | based on the new data on semileptonic B → D ∗ ℓ ν ℓ decays by…”
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Updates on the determination of $$\vert V_{cb} \vert ,$$ $$R(D^{})$$ and $$\vert V_{ub} \vert /\vert V_{cb} \vert by Martinelli, G., Simula, S., Vittorio, L.

“…Abstract We present an updated determination of the values of $$\vert V_{cb} \vert ,$$ | V cb | , $$R(D^*)$$ R ( D ∗ ) and $$\vert V_{ub} \vert /\vert V_{cb}…”
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Building Sister Chromatid Cohesion: Smc3 Acetylation Counteracts an Antiestablishment Activity by Rowland, Benjamin D., Roig, Maurici B., Nishino, Tatsuya, Kurze, Alexander, Uluocak, Pelin, Mishra, Ajay, Beckouët, Frédéric, Underwood, Philippa, Metson, Jean, Imre, Richard, Mechtler, Karl, Katis, Vittorio L., Nasmyth, Kim

“…Cohesin's Smc1, Smc3, and Scc1 subunits form a tripartite ring that entraps sister DNAs. Scc3, Pds5, and Rad61 (Wapl) are regulatory subunits that control this…”
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An Smc3 Acetylation Cycle Is Essential for Establishment of Sister Chromatid Cohesion by Beckouët, Frederic, Hu, Bin, Roig, Maurici B., Sutani, Takashi, Komata, Makiko, Uluocak, Pelin, Katis, Vittorio L., Shirahige, Katsuhiko, Nasmyth, Kim

“…Sister chromatid cohesion is thought to involve entrapment of sister DNAs by a tripartite ring composed of the cohesin subunits Smc1, Smc3, and Scc1…”
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Rec8 Phosphorylation by Casein Kinase 1 and Cdc7-Dbf4 Kinase Regulates Cohesin Cleavage by Separase during Meiosis by Katis, Vittorio L., Lipp, Jesse J., Imre, Richard, Bogdanova, Aliona, Okaz, Elwy, Habermann, Bianca, Mechtler, Karl, Nasmyth, Kim, Zachariae, Wolfgang

“…During meiosis, two rounds of chromosome segregation after a single round of DNA replication produce haploid gametes from diploid precursors. At meiosis I,…”
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Learning curve in retroperitoneal sarcoma surgery by Samà, Laura, Kumar, Sonia, Ruspi, Laura, Sicoli, Federico, D'Amato, Vittoria, Mintemur, Ömer, Renne, Salvatore L., Quagliuolo, Vittorio L., Cananzi, Ferdinando CM

“…Retroperitoneal sarcoma (RPS) surgery poses unique challenges. This retrospective study aimed to analyze the learning curve (LC) in RPS surgery, assessing the…”
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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM by Bashore, Frances M, Katis, Vittorio L, Du, Yuhong, Sikdar, Arunima, Wang, Dongxue, Bradshaw, William J, Rygiel, Karolina A, Leisner, Tina M, Chalk, Rod, Mishra, Swati, Williams, C Andrew, Gileadi, Opher, Brennan, Paul E, Wiley, Jesse C, Gockley, Jake, Cary, Gregory A, Carter, Gregory W, Young, Jessica E, Pearce, Kenneth H, Fu, Haian, Axtman, Alison D

“…RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative…”
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Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2 by Bradshaw, William J, Kennedy, Emma C, Moreira, Tiago, Smith, Luke A, Chalk, Rod, Katis, Vittorio L, Benesch, Justin L P, Brennan, Paul E, Murphy, Emma J, Gileadi, Opher

“…SHIP1, an inositol 5-phosphatase, plays a central role in cellular signaling. As such, it has been implicated in many conditions. Exploiting SHIP1 as a drug…”
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Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I by Riedel, C.G, Katis, V.L, Katou, Y, Mori, S, Itoh, T, Helmhart, W, Galova, M, Petronczki, M, Gregan, J, Cetin, B

“…Segregation of homologous maternal and paternal centromeres to opposite poles during meiosis I depends on post-replicative crossing over between homologous…”
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Discovery of FERM domain protein–protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer’s disease by Du, Yuhong, Bradshaw, William J., Leisner, Tina M., Annor-Gyamfi, Joel K., Qian, Kun, Bashore, Frances M., Sikdar, Arunima, Nwogbo, Felix O., Ivanov, Andrey A., Frye, Stephen V., Gileadi, Opher, Brennan, Paul E., Levey, Allan I., Axtman, Alison D., Pearce, Kenneth H., Fu, Haian, Katis, Vittorio L.

“…Proteomic studies have identified moesin (MSN), a protein containing a four-point-one, ezrin, radixin, moesin (FERM) domain, and the receptor CD44 as hub…”
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Development of a time-resolved fluorescence resonance energy transfer ultra-high throughput screening assay targeting SYK and FCER1G interaction by Du, Yuhong, Wang, Dongxue, Katis, Vittorio L., Zoeller, Elizabeth L., Qui, Min, Levey, Allan I., Gileadi, Opher, Fu, Haian

“…The spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) interaction has a major role in the normal innate and…”
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Cdc14 Phosphatase Induces rDNA Condensation and Resolves Cohesin-Independent Cohesion during Budding Yeast Anaphase by Sullivan, Matt, Higuchi, Toru, Katis, Vittorio L, Uhlmann, Frank

“…At anaphase onset, the protease separase triggers chromosome segregation by cleaving the chromosomal cohesin complex. Here, we show that cohesin destruction in…”
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Predictive Value of MRP-1 in Localized High-Risk Soft Tissue Sarcomas: A Translational Research Associated to ISG-STS 1001 Randomized Phase III Trial by Martin-Broto, Javier, Lopez-Alvarez, Maria, Moura, David S, Ramos, Rafael, Collini, Paola, Romagosa, Cleofe, Bagué, Silvia, Renne, Salvatore L, Barisella, Marta, Velasco, Valerie, Coindre, Jean-Michel, Lopez-Lopez, Daniel, Dopazo, Joaquin, Gambarotti, Marco, Braglia, Luca, Merlo, Domenico Franco, Palmerini, Emanuela, Stacchiotti, Silvia, Quagliuolo, Vittorio L, Lopez-Pousa, Antonio, Grignani, Giovanni, Blay, Jean-Yves, Brunello, Antonella, Gutierrez, Antonio, Valverde, Claudia, Hindi, Nadia, Dei Tos, Angelo Paolo, Picci, Piero, Casali, Paolo G, Gronchi, Alessandro

“…MRP-1 is implicated in multidrug resistance and was described as prognostic in high-risk patients with soft-tissue sarcoma (STS) in a previous study. The…”
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Maintenance of Cohesin at Centromeres after Meiosis I in Budding Yeast Requires a Kinetochore-Associated Protein Related to MEI-S332 by Katis, Vittorio L, Galova, Marta, Rabitsch, Kirsten P, Gregan, Juraj, Nasmyth, Kim

“…Background: The halving of chromosome number that occurs during meiosis depends on three factors. First, homologs must pair and recombine. Second, sister…”
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Phase I/II Study of Refametinib (BAY 86-9766) in Combination with Gemcitabine in Advanced Pancreatic cancer by Van Laethem, Jean-Luc, Riess, Hanno, Jassem, Jacek, Haas, Michael, Martens, Uwe M., Weekes, Colin, Peeters, Marc, Ross, Paul, Bridgewater, John, Melichar, Bohuslav, Cascinu, Stefano, Saramak, Piotr, Michl, Patrick, Van Brummelen, David, Zaniboni, Alberto, Schmiegel, Wollf, Dueland, Svein, Giurescu, Marius, Garosi, Vittorio L., Roth, Katrin, Schulz, Anke, Seidel, Henrik, Rajagopalan, Prabhu, Teufel, Michael, Childs, Barrett H.

“…Background Activating KRAS mutations are reported in up to 90% of pancreatic cancers. Refametinib potently inhibits MEK1/2, part of the MAPK signaling pathway…”
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Polo-like kinase Cdc5 promotes chiasmata formation and cosegregation of sister centromeres at meiosis I by Nasmyth, Kim, Clyne, Rosemary K, Katis, Vittorio L, Jessop, Lea, Benjamin, Kirsten R, Herskowitz, Ira, Lichten, Michael

“…During meiosis, two rounds of chromosome segregation occur after a single round of DNA replication, producing haploid progeny from diploid progenitors. Three…”
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strange case of a biofilm-forming strain of Pichia fermentans, which controls Monilinia brown rot on apple but is pathogenic on peach fruit by Giobbe, Sara, Marceddu, Salvatore, Scherm, Barbara, Zara, Giacomo, Mazzarello, Vittorio L, Budroni, Marilena, Migheli, Quirico

“…A biofilm-forming strain of Pichia fermentans proved to be most effective in controlling brown rot on apple fruit when coinoculated into artificial wounds with…”
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FAS2FURIOUS: Moderate-Throughput Secreted Expression of Difficult Recombinant Proteins in Drosophila S2 Cells by Coker, Jesse A, Katis, Vittorio L, Fairhead, Michael, Schwenzer, Anja, Clemmensen, Stine B, Frandsen, Bent U, de Jongh, Willem A, Gileadi, Opher, Burgess-Brown, Nicola A, Marsden, Brian D, Midwood, Kim S, Yue, Wyatt W

“…Recombinant protein expression in eukaryotic insect cells is a powerful approach for producing challenging targets. However, due to incompatibility with…”
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Development of SYK NanoBRET cellular target engagement assays for gain–of–function variants by Jacob L. Capener, James D. Vasta, Vittorio L. Katis, Ani Michaud, Michael T. Beck, Sabrina C. D. Daglish, Sarit Cohen-Kedar, Sarit Cohen-Kedar, Efrat Shaham Barda, Efrat Shaham Barda, Stefanie Howell, Iris Dotan, Iris Dotan, Matthew B. Robers, Alison D. Axtman, Frances M. Bashore

“…Spleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase that is activated by phosphorylation events downstream of FcR, B-cell and T-cell receptors,…”
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