Search Results - "Vitiello, Laura"
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Immunoregulation through extracellular nucleotides
Published in Blood (19-07-2012)“…Extracellular ATP (eATP), the most abundant among nucleotides, can act as a mediator during inflammatory responses by binding to plasmamembrane P2 purinergic…”
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2
Immunological and homeostatic pathways of alpha -1 antitrypsin: a new therapeutic potential
Published in Frontiers in immunology (19-08-2024)“…α -1 antitrypsin (A1AT) is a 52 kDa acute-phase glycoprotein belonging to the serine protease inhibitor superfamily (SERPIN). It is primarily synthesized by…”
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3
Identification of MOR-Positive B Cell as Possible Innovative Biomarker (Mu Lympho-Marker) for Chronic Pain Diagnosis in Patients with Fibromyalgia and Osteoarthritis Diseases
Published in International journal of molecular sciences (22-02-2020)“…Fibromyalgia (FM) diagnosis follows the American College of Rheumatology (ACR) criteria, based on clinical evaluation and written questionnaires without any…”
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4
Very-low-calorie ketogenic diet vs hypocaloric balanced diet in the prevention of high-frequency episodic migraine: the EMIKETO randomized, controlled trial
Published in Journal of translational medicine (04-10-2023)“…Abstract Background Migraine is the second world’s cause of disability. Among non-pharmacological treatments, nutritional intervention, particularly ketogenic…”
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Nicotine in Combination with SARS-CoV-2 Affects Cells Viability, Inflammatory Response and Ultrastructural Integrity
Published in International journal of molecular sciences (22-08-2022)“…The aims of our study are to: (i) investigate the ability of nicotine to modulate the expression level of inflammatory cytokines in A549 cells infected with…”
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6
Daily Vegetables Intake and Response to COPD Rehabilitation. The Role of Oxidative Stress, Inflammation and DNA Damage
Published in Nutrients (01-08-2021)“…Chronic obstructive pulmonary disease (COPD) is a respiratory disease associated with airways inflammation and lung parenchyma fibrosis. The primary goals of…”
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7
Long Lasting Cellular Immune Response Induced by mRNA Vaccination: Implication for Prevention Strategies
Published in Frontiers in immunology (10-03-2022)“…As the COVID19 pandemic continues to spread and vaccinations are administered throughout the world at different rates and with different strategies,…”
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CXCL12 prolongs naive CD4 + T lymphocytes survival via activation of PKA, CREB and Bcl2 and BclXl up-regulation
Published in International journal of cardiology (01-12-2016)“…Abstract Background Naive T lymphocytes recirculate through the body, traveling from secondary lymphoid organs through tissues and via lymphatic vessels and…”
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SIRT5 Activation and Inorganic Phosphate Binding Reduce Cancer Cell Vitality by Modulating Autophagy/Mitophagy and ROS
Published in Antioxidants (01-08-2023)“…Cancer cells show increased glutamine consumption. The glutaminase (GLS) enzyme controls a limiting step in glutamine catabolism. Breast tumors, especially the…”
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10
Altered Tregs Differentiation and Impaired Autophagy Correlate to Atherosclerotic Disease
Published in Frontiers in immunology (13-03-2020)“…Atherosclerosis is a progressive vascular disease representing the primary cause of morbidity and mortality in developed countries. Formerly, atherosclerosis…”
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The Shigella flexneri virulence factor apyrase is released inside eukaryotic cells to hijack host cell fate
Published in Microbiology spectrum (12-12-2023)“…In this paper, we demonstrated that apyrase is released within the host cell cytoplasm during infection to target the intracellular ATP pool. By degrading…”
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Doxorubicin-Induced Cardiac Senescence Is Alleviated Following Treatment with Combined Polyphenols and Micronutrients through Enhancement in Mitophagy
Published in Cells (Basel, Switzerland) (01-11-2023)“…Oxidative stress and impaired mitophagy are the hallmarks of cardiomyocyte senescence. Specifically, a decrease in mitophagic flux leads to the accumulation of…”
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Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery
Published in Cells (Basel, Switzerland) (22-02-2023)“…Life on Earth has evolved in the presence of a gravity constraint. Any change in the value of such a constraint has important physiological effects. Gravity…”
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An Observational Study on Chronic Pain Biomarkers in Fibromyalgia and Osteoarthritis Patients: Which Role for Mu Opioid Receptor's Expression on NK Cells?
Published in Biomedicines (01-03-2023)“…The evaluation of chronic pain is challenging because of the lack of specific biomarkers. We identified the Mu opioid receptor-positive (Mu+) B cell percentage…”
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BNT162b2 mRNA COVID-19 Vaccine Does Not Impact the Honeymoon Phase in Type 1 Diabetes: A Case Report
Published in Vaccines (Basel) (01-07-2022)“…Type 1 diabetes (T1D), which is caused by the autoimmune destruction of insulin-secreting pancreatic beta cells, represents a high-risk category requiring…”
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Central Modulation of Selective Sphingosine-1-Phosphate Receptor 1 Ameliorates Experimental Multiple Sclerosis
Published in Cells (Basel, Switzerland) (22-05-2020)“…Future treatments of multiple sclerosis (MS), a chronic autoimmune neurodegenerative disease of the central nervous system (CNS), aim for simultaneous early…”
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Molecular evidence for a thymus-independent partial T cell development in a FOXN1-/- athymic human fetus
Published in PloS one (09-12-2013)“…The thymus is the primary organ able to support T cell ontogeny, abrogated in FOXN1(-/-) human athymia. Although evidence indicates that in animal models T…”
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Role of the common γ chain in cell cycle progression of human malignant cell lines
Published in International immunology (01-03-2012)“…The γ-chain (γc) is a transducing element shared between several cytokine receptors whose alteration causes X-linked severe combined immunodeficiency…”
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Dendritic cells/natural killer cross-talk: a novel target for human immunodeficiency virus type-1 protease inhibitors
Published in PloS one (10-06-2010)“…HIV-1 Protease Inhibitors, namely PIs, originally designed to inhibit HIV-1 aspartic protease, can modulate the immune response by mechanisms largely unknown,…”
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The Interplay between Chronic Pain, Opioids, and the Immune System
Published in The Neuroscientist (01-12-2022)“…Chronic pain represents one of the most serious worldwide medical problems, in terms of both social and economic costs, often causing severe and intractable…”
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