Search Results - "Vitiello, Gerardo A"
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Targeting the interleukin-17 immune axis for cancer immunotherapy
Published in The Journal of experimental medicine (06-01-2020)“…The role of IL-17 in cancer remains controversial. Emerging evidence suggests that during early oncogenesis IL-17 supports tumor growth, whereas in established…”
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The Role of the Microbiome in Immunologic Development and its Implication For Pancreatic Cancer Immunotherapy
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2019)“…Our understanding of the microbiome and its role in immunity, cancer initiation, and cancer progression has evolved significantly over the past century. The…”
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Mitochondrial Inhibition Augments the Efficacy of Imatinib by Resetting the Metabolic Phenotype of Gastrointestinal Stromal Tumor
Published in Clinical cancer research (15-02-2018)“…Imatinib dramatically reduces gastrointestinal stromal tumor (GIST) F-FDG uptake, providing an early indicator of treatment response. Despite decreased glucose…”
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Genetic Variation in Choline-Metabolizing Enzymes Alters Choline Metabolism in Young Women Consuming Choline Intakes Meeting Current Recommendations
Published in International journal of molecular sciences (01-02-2017)“…Single nucleotide polymorphisms (SNPs) in choline metabolizing genes are associated with disease risk and greater susceptibility to organ dysfunction under…”
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Endovascular Treatment of Spontaneous Renal Artery Dissection After Failure of Medical Management
Published in Vascular and endovascular surgery (01-10-2017)“…Spontaneous renal artery dissection (SRAD) is a rare disease with approximately 200 cases reported in the literature. The severity of renal compromise, the…”
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Acral Lentiginous Melanoma: A United States Multi-Center Substage Survival Analysis
Published in Cancer control (2021)“…Background Acral lentiginous melanoma is associated with worse survival than other subtypes of melanoma. Understanding prognostic factors for survival and…”
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Does the amount of time medical students spend in the operating room during the general surgery core clerkship affect their career decision?
Published in The American journal of surgery (01-07-2015)“…Abstract Background The amount of time medical students (MS) spend in the operating room (OR) during their general surgery core clerkship has not been…”
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Dermatofibrosarcoma Protuberans: What Is This?
Published in The Surgical clinics of North America (01-08-2022)“…Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive dermal-based sarcoma. Metastatic potential is extremely low, primarily in the setting of…”
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Differential immune profiles distinguish the mutational subtypes of gastrointestinal stromal tumor
Published in The Journal of clinical investigation (01-05-2019)“…Gastrointestinal stromal tumor (GIST) is the most common human sarcoma, frequently characterized by an oncogenic mutation in the KIT or platelet-derived growth…”
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Do Medical Students in the Operating Room Affect Patient Care? An Analysis of One Institution’s Experience Over the Past Five Years
Published in Journal of surgical education (01-11-2014)“…Background Medical students are active learners in operating rooms during medical school. This observational study seeks to investigate the effect of medical…”
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Systemic therapy for duodenal adenocarcinoma: An analysis of the National Cancer Database (NCDB)
Published in Surgery (01-07-2022)“…National Comprehensive Cancer Network guidelines recommend resection and adjuvant chemotherapy for patients with locally advanced duodenal adenocarcinoma…”
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Surgical Treatment of Patients with Poorly Differentiated Pancreatic Neuroendocrine Carcinoma: An NCDB Analysis
Published in Annals of surgical oncology (01-06-2022)“…Background Consensus guidelines discourage resection of poorly differentiated pancreatic neuroendocrine carcinoma (panNEC) given its association with poor…”
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Myosin Light-Chain Kinase Inhibition Potentiates the Antitumor Effects of Avapritinib in PDGFRA D842V-Mutant Gastrointestinal Stromal Tumor
Published in Clinical cancer research (01-06-2023)“…To create an in vivo model of PDGFRA D842V-mutant gastrointestinal stromal tumor (GIST) and identify the mechanism of tumor persistence following avapritinib…”
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Oncogenic kinase inhibition limits Batf3-dependent dendritic cell development and antitumor immunity
Published in The Journal of experimental medicine (03-06-2019)“…Gastrointestinal stromal tumor (GIST) is driven by an activating mutation in the proto-oncogene. Using a mouse model of GIST and human specimens, we show that…”
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The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor
Published in Oncogene (03-12-2020)“…Gastrointestinal stromal tumor (GIST) is the most common human sarcoma and arises in the gastrointestinal tract. Most GISTs are caused by activating mutations…”
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ASO Visual Abstract: Surgical Treatment of Patients with Poorly Differentiated Pancreatic Neuroendocrine Carcinoma—An NCDB Analysis
Published in Annals of surgical oncology (01-06-2022)Get full text
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Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis
Published in The FASEB journal (01-10-2016)“…ABSTRACT Although single nucleotide polymorphisms (SNPs) in folate‐mediated pathways predict susceptibility to choline deficiency during severe choline…”
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Patient metabolic profile defined by liver and muscle 18F-FDG PET avidity is independently associated with overall survival in gastric cancer
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-05-2024)“…Background PET–CT-based patient metabolic profiling is a novel concept to incorporate patient-specific metabolism into gastric cancer care. Methods Staging…”
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Surgical resection of early stage hepatocellular carcinoma improves patient survival at safety net hospitals
Published in Journal of surgical oncology (01-03-2021)“…Background and Objectives Surgical resection is indicated for hepatocellular carcinoma (HCC) patients with Child A cirrhosis. We hypothesize that surgical…”
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Utility of Prostate Cancer Screening in Kidney Transplant Candidates
Published in Journal of the American Society of Nephrology (01-07-2016)“…Screening recommendations for prostate cancer remain controversial, and no specific guidelines exist for screening in renal transplant candidates. To examine…”
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