Search Results - "Vita, Nicole"

Targeting Helicobacter pylori for antibacterial drug discovery with novel therapeutics by Vita, Nicole A, Anderson, Shelby M, LaFleur, Michael D, Lee, Richard E

“…Helicobacter pylori is an important human pathogen with increasing antimicrobial resistance to standard-of-care antibiotics. Treatment generally includes a…”
Get full text

Identification of Inhibitors of Fungal Fatty Acid Biosynthesis by DeJarnette, Christian, Meyer, Chris J., Jenner, Alexander R., Butts, Arielle, Peters, Tracy, Cheramie, Martin N., Phelps, Gregory A., Vita, Nicole A., Loudon-Hossler, Victoria C., Lee, Richard E., Palmer, Glen E.

“…Fungal fatty acid (FA) synthase and desaturase enzymes are essential for the growth and virulence of human fungal pathogens. These enzymes are structurally…”
Get full text

The Discovery and Development of Thienopyrimidines as Inhibitors of Helicobacter pylori That Act through Inhibition of the Respiratory Complex I by Mugengana, Alex K, Vita, Nicole A, Brown Gandt, Autumn, Moran, Kevin, Agyapong, George, Sharma, Lalit K, Griffith, Elizabeth C, Liu, Jiuyu, Yang, Lei, Gavrish, Ekaterina, Hevener, Kirk E, LaFleur, Michael D, Lee, Richard E

“…The successful treatment of Helicobacter pylori infections is becoming increasingly difficult due to the rise of resistance against current broad spectrum…”
Get full text

Nurses’ Perceptions of the Quality of Procedural Sedation in Children Comparing Different Pharmacological Regimens by Curatola, Antonietta, D’Agostin, Martina, Favaretto, Elena, Vittori, Giada, Vidonis, Viviana, Strajn, Tamara, De Vita, Nicole, Saccari, Alessia, Barbi, Egidio, Cortellazzo Wiel, Luisa

“…Nurses play a pivotal role during pediatric procedural sedation and their perspective is an important indicator for the quality of care. The aim of this study…”
Get full text

Impact of Body Mass Index on Outcomes in Pediatric Allogeneic Hematopoietic Stem Cell Transplantation Recipients: A Single-Center Retrospective Study by Braidotti, Stefania, Curci, Debora, Zanon, Davide, Maestro, Alessandra, Longo, Antonella, De Vita, Nicole, Maximova, Natalia

“…Background: Pediatric patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) face several risk factors influencing transplantation…”
Get full text

Nurse-Driven Interventions Reduce Central Line-Associated Bloodstream Infection Close to Zero in One Pediatric Oncologic Facility: A Single-Center Retrospective Observational Study by Turoldo, Federico, Longo, Antonella, Sala, Mariavittoria, Valentini, Denis, De Vita, Nicole, Toniutti, Sara, Zuppel, Loredana, Maximova, Natalia

“…Central line-associated bloodstream infections (CLABSIs) are critical infectious complications among pediatric hematology-oncology patients, and the management…”
Get full text

Computer-Aided Drug Discovery for Helicobacter pylori by Vita, Nicole A

“…Helicobacter pylori is a high-priority drug-resistant pathogen and is currently the only bacteria considered to be a class I carcinogen and there is a critical…”
Get full text

Abstract ND03: Discovery of RMC-9805, an oral, covalent tri-complex KRASG12D(ON) inhibitor by Knox, John E., Burnett, G. Leslie, Weller, Caroline, Jiang, Lingyan, Zhang, Dongyu, Vita, Nicole, Marquez, Abby, Seamon, Kyle J., Gould, Andrea, Menard, Marie, Quintana, Elsa, Chen, Zhe, Wang, Zhican, Wang, Zhengping, Koltun, Elena S., Singh, Malika, Jiang, Jingjing, Wildes, David, Smith, Jacqueline A.M., Gill, Adrian L.

“…RASG12D mutant cancers represent a significant unmet medical need with 55,000 new diagnoses annually in the US. The RASG12D mutation increases the abundance of…”
Get full text