Search Results - "Vissers, Johannes P.C."

Application of Predicted Collisional Cross Section to Metabolome Databases to Probabilistically Describe the Current and Future Ion Mobility Mass Spectrometry by Broeckling, Corey D, Yao, Linxing, Isaac, Giorgis, Gioioso, Marisa, Ianchis, Valentin, Vissers, Johannes P.C

“…Metabolomics is a powerful phenotyping platform with potential for high-throughput analyses. The primary technology for metabolite profiling is mass…”
Get full text

Database searching and accounting of multiplexed precursor and product ion spectra from the data independent analysis of simple and complex peptide mixtures by Li, Guo-Zhong, Vissers, Johannes P.C, Silva, Jeffrey C, Golick, Dan, Gorenstein, Marc V, Geromanos, Scott J

“…A novel database search algorithm is presented for the qualitative identification of proteins over a wide dynamic range, both in simple and complex biological…”
Get full text

detection, correlation, and comparison of peptide precursor and product ions from data independent LC-MS with data dependant LC-MS/MS by Geromanos, Scott J, Vissers, Johannes P.C, Silva, Jeffrey C, Dorschel, Craig A, Li, Guo-Zhong, Gorenstein, Marc V, Bateman, Robert H, Langridge, James I

“…The detection, correlation, and comparison of peptide and product ions from a data independent LC-MS acquisition strategy with data dependent LC-MS/MS is…”
Get full text

BASIS: High-performance bioinformatics platform for processing of large-scale mass spectrometry imaging data in chemically augmented histology by Veselkov, Kirill, Sleeman, Jonathan, Claude, Emmanuelle, Vissers, Johannes P. C., Galea, Dieter, Mroz, Anna, Laponogov, Ivan, Towers, Mark, Tonge, Robert, Mirnezami, Reza, Takats, Zoltan, Nicholson, Jeremy K., Langridge, James I.

“…Mass Spectrometry Imaging (MSI) holds significant promise in augmenting digital histopathologic analysis by generating highly robust big data about the…”
Get full text

Specificity of the osmotic stress response in Candida albicans highlighted by quantitative proteomics by Jacobsen, Mette D., Beynon, Robert J., Gethings, Lee A., Claydon, Amy J., Langridge, James I., Vissers, Johannes P. C., Brown, Alistair J. P., Hammond, Dean E.

“…Stress adaptation is critical for the survival of microbes in dynamic environments, and in particular, for fungal pathogens to survive in and colonise host…”
Get full text

Using ion purity scores for enhancing quantitative accuracy and precision in complex proteomics samples by Geromanos, Scott J., Hughes, Chris, Ciavarini, Steven, Vissers, Johannes P. C., Langridge, James I.

“…To accurately determine the quantitative change of peptides and proteins in complex proteomics samples requires knowledge of how well each ion has been…”
Get full text

Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicity by Rodríguez-Suárez, Eva, Gonzalez, Esperanza, Hughes, Chris, Conde-Vancells, Javier, Rudella, Andrea, Royo, Felix, Palomo, Laura, Elortza, Felix, Lu, Shelly C., Mato, Jose M., Vissers, Johannes P.C., Falcón-Pérez, Juan M.

“…Extracellular vesicles have created great interest as possible source of biomarkers for different biological processes and diseases. Although the biological…”
Get full text

Elevation of glycoprotein nonmetastatic melanoma protein B in type 1 Gaucher disease patients and mouse models by Kramer, Gertjan, Wegdam, Wouter, Donker‐Koopman, Wilma, Ottenhoff, Roelof, Gaspar, Paulo, Verhoek, Marri, Nelson, Jessica, Gabriel, Tanit, Kallemeijn, Wouter, Boot, Rolf G., Laman, Jon D., Vissers, Johannes P.C., Cox, Timothy, Pavlova, Elena, Moran, Mary Teresa, Aerts, Johannes M., Eijk, Marco

“…Gaucher disease is caused by inherited deficiency of lysosomal glucocerebrosidase. Proteome analysis of laser‐dissected splenic Gaucher cells revealed…”
Get full text

Nonionic detergent phase extraction for the proteomic analysis of heart membrane proteins using label-free LC-MS by Donoghue, Pamela M, Hughes, Chris, Vissers, Johannes P.C, Langridge, James I, Dunn, Michael J

“…Heart diseases resulting in heart failure are among the leading causes of morbidity and mortality in the Western world and can result from either systemic…”
Get full text

Survey of bacterial proteins released in cheese: a proteomic approach by Gagnaire, Valérie, Piot, Michel, Camier, Bénédicte, Vissers, Johannes P.C, Jan, Gwénaël, Léonil, Joëlle

“…During the ripening of Emmental cheese, the bacterial ecosystem confers its organoleptic characteristics to the evolving curd both by the action of the living…”
Get full text

Microcolumn liquid chromatography: instrumentation, detection and applications by Vissers, Johannes P.C., Claessens, Henk A., Cramers, Carel A.

“…This review discusses many different aspects of microcolumn liquid chromatography (LC) and reflects the areas of microcolumn LC research interest over the past…”
Get full text

Absolute Quantification of Proteins by LCMSE by Silva, Jeffrey C., Gorenstein, Marc V., Li, Guo-Zhong, Vissers, Johannes P.C., Geromanos, Scott J.

“…Relative quantification methods have dominated the quantitative proteomics field. There is a need, however, to conduct absolute quantification studies to…”
Get full text

A novel interface for variable flow nanoscale LC/MS/MS for improved proteome coverage by Vissers, Johannes P.C, Blackburn, R.Kevin, Moseley, M.Arthur

“…A variable flow “peak trapping” liquid chromatography (LC) interface has been developed for the coupling of nanoscale LC to electrospray ionization mass…”
Get full text

Predicting ion mobility collision cross sections and assessing prediction variation by combining conventional and data driven modeling by Bouwmeester, Robbin, Richardson, Keith, Denny, Richard, Wilson, Ian D., Degroeve, Sven, Martens, Lennart, Vissers, Johannes P.C.

“…The use of collision cross section (CCS) values derived from ion mobility studies is proving to be an increasingly important tool in the characterization and…”
Get full text

The Hamaker and the Lifshitz approaches for the Van der Waals interaction between particles of composite materials dispersed in a medium by Laven, Jozua, Vissers, Johannes P.C

“…Based on the superpositional principle of the classical Hamaker–De Boer approach to the Van der Waals interaction, an equation for the interaction energy…”
Get full text

Increasing coverage of the urinary polar metabolome using ultra high-performance hydrophobic interaction liquid chromatography combined with linear and cyclic travelling wave ion mobility and mass spectrometry by King, Adam, Gethings, Lee A., Vissers, Johannes P.C., Plumb, Robert S., Wilson, Ian D.

“…•The metabolic phenotyping of the polar metabolites excreted in urine is challenging.•Urinalysis using HILIC is currently the method of choice for polar…”
Get full text

Use of Cyclic Ion Mobility Spectrometry (cIM)-Mass Spectrometry to Study the Intramolecular Transacylation of Diclofenac Acyl Glucuronide by Higton, David, Palmer, Martin E, Vissers, Johannes P. C, Mullin, Lauren G, Plumb, Robert S, Wilson, Ian D

“…1-β-O-Acyl-glucuronides (AGs) are common metabolites of carboxylic acid-containing xenobiotics, including, e.g., many nonsteroidal anti-inflammatory drugs…”
Get full text

An Analytical Perspective on Protein Analysis and Discovery Proteomics by Ion Mobility-Mass Spectrometry by Vissers, Johannes P C, McCullagh, Michael

“…Ion mobility combined with mass spectrometry (IM-MS) is a powerful technique for the analysis of biomolecules and complex mixtures. This chapter reviews the…”
Get more information

Determination of Protein Haptenation by Chemical Sensitizers Within the Complexity of the Human Skin Proteome by Parkinson, Erika, Aleksic, Maja, Cubberley, Richard, Kaur-Atwal, Gushinder, Vissers, Johannes P C, Skipp, Paul

“…Abstract Skin sensitization associated with the development of allergic contact dermatitis occurs via a number of specific key events at the cellular level…”
Get full text

Ion Mobility Tandem Mass Spectrometry Enhances Performance of Bottom-up Proteomics by Helm, Dominic, Vissers, Johannes P.C., Hughes, Christopher J., Hahne, Hannes, Ruprecht, Benjamin, Pachl, Fiona, Grzyb, Arkadiusz, Richardson, Keith, Wildgoose, Jason, Maier, Stefan K., Marx, Harald, Wilhelm, Mathias, Becher, Isabelle, Lemeer, Simone, Bantscheff, Marcus, Langridge, James I., Kuster, Bernhard

“…One of the limiting factors in determining the sensitivity of tandem mass spectrometry using hybrid quadrupole orthogonal acceleration time-of-flight…”
Get full text