Search Results - "Visser, W Edward"
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ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of hyperthyroidism and hypothyroidism
Published in European journal of endocrinology (01-07-2020)“…This manuscript provides guidance on the management of thyroid dysfunction during the COVID-19 pandemic. Autoimmune thyroid diseases are not linked to…”
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Thyroid Hormone Transporters
Published in Endocrine reviews (01-04-2020)“…Abstract Thyroid hormone transporters at the plasma membrane govern intracellular bioavailability of thyroid hormone. Monocarboxylate transporter (MCT) 8 and…”
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Triiodothyroacetic acid in health and disease
Published in Journal of endocrinology (01-08-2017)“…Thyroid hormone (TH) is crucial for development and metabolism of many tissues. The physiological relevance and therapeutic potential of TH analogs have gained…”
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Genetic Determination of the Hypothalamic-Pituitary-Thyroid Axis: Where Do We Stand?
Published in Endocrine reviews (01-04-2015)“…For a long time it has been known that both hypo- and hyperthyroidism are associated with an increased risk of morbidity and mortality. In recent years, it has…”
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Minireview: Thyroid Hormone Transporters: The Knowns and the Unknowns
Published in Molecular endocrinology (Baltimore, Md.) (01-01-2011)“…The effects of thyroid hormone (TH) on development and metabolism are exerted at the cellular level. Metabolism and action of TH take place intracellularly,…”
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Interpretation of thyroid function tests during pregnancy
Published in Baillière's best practice & research. Clinical endocrinology & metabolism (01-07-2020)“…Thyroid hormones are crucial for normal pregnancy and fetal development. Large physiological changes occur during pregnancy, posing challenges for the correct…”
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Association between thyroid function and osteoarthritis: A population-based cohort study
Published in Osteoarthritis and cartilage (11-11-2024)“…Previous genetic and animal studies indicated a causal role of thyroid hormones in osteoarthritis (OA), which has not been observed in the general population…”
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Hypothyroxinemia and TPO-Antibody Positivity Are Risk Factors for Premature Delivery: The Generation R Study
Published in The journal of clinical endocrinology and metabolism (01-11-2013)“…Context: Premature delivery is an important risk factor for child mortality and psychiatric, metabolic, and cardiovascular disease later in life. In the…”
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Monocarboxylate transporter 8 deficiency: update on clinical characteristics and treatment
Published in Endocrine (01-03-2021)“…Defective thyroid hormone transport due to deficiency in thyroid hormone transporter monocarboxylate transporter 8 (MCT8) results in severe neurodevelopmental…”
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Thyroid Hormone Transporters in Pregnancy and Fetal Development
Published in International journal of molecular sciences (01-12-2022)“…Thyroid hormone is essential for fetal (brain) development. Plasma membrane transporters control the intracellular bioavailability of thyroid hormone. In the…”
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Comparing the Prognostic Value of the Eighth Edition of the American Joint Committee on Cancer/Tumor Node Metastasis Staging System Between Papillary and Follicular Thyroid Cancer
Published in Thyroid (New York, N.Y.) (01-08-2018)“…Recently, the eighth edition of the American Joint Committee on Cancer (AJCC)/tumor node metastasis (TNM) staging system for differentiated thyroid cancer…”
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The influence of age on disease outcome in 2015 ATA high-risk differentiated thyroid cancer patients
Published in European journal of endocrinology (01-09-2021)“…Objective Recent research suggests that the addition of age improves the 2015 American Thyroid Association (ATA) Risk Stratification System for differentiated…”
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Thyroid Function Within the Normal Range and the Risk of Depression: A Population-Based Cohort Study
Published in The journal of clinical endocrinology and metabolism (01-04-2014)“…Context: Overt hypo- and hyperthyroidism are associated with an increased risk of depression. Little is known about the effects of variation in thyroid…”
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In Vitro and Mouse Studies Supporting Therapeutic Utility of Triiodothyroacetic Acid in MCT8 Deficiency
Published in Molecular endocrinology (Baltimore, Md.) (01-12-2014)“…Monocarboxylate transporter 8 (MCT8) transports thyroid hormone (TH) across the plasma membrane. Mutations in MCT8 result in the Allan-Herndon-Dudley syndrome,…”
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Outward-Open Model of Thyroid Hormone Transporter Monocarboxylate Transporter 8 Provides Novel Structural and Functional Insights
Published in Endocrinology (Philadelphia) (01-10-2017)“…Monocarboxylate transporter 8 (MCT8) facilitates cellular uptake and efflux of thyroid hormone (TH). Mutations in MCT8 result in severe intellectual and motor…”
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A Mass Spectrometry-Based Panel of Nine Thyroid Hormone Metabolites in Human Serum
Published in Clinical chemistry (Baltimore, Md.) (01-04-2020)“…Abstract Background While thyroxine (T4), 3,3’,5-triiodothyronine (T3), and 3,3’,5’-triiodothyronine (rT3) have routine methods available for evaluating…”
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Ethnic Differences in Maternal Thyroid Parameters during Pregnancy: The Generation R Study
Published in The journal of clinical endocrinology and metabolism (01-09-2013)“…Context: Abnormal maternal thyroid function during pregnancy is associated with various complications. International guidelines advocate the use of…”
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Monocarboxylate Transporter 8 Deficiency: From Pathophysiological Understanding to Therapy Development
Published in Frontiers in endocrinology (Lausanne) (01-09-2021)“…Genetic defects in the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) result in MCT8 deficiency. This disorder is characterized by a…”
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A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function
Published in PLoS genetics (01-02-2013)“…Thyroid hormone is essential for normal metabolism and development, and overt abnormalities in thyroid function lead to common endocrine disorders affecting…”
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Triac Treatment Prevents Neurodevelopmental and Locomotor Impairments in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice
Published in International journal of molecular sciences (01-02-2023)“…Patients with inactive thyroid hormone (TH) transporter MCT8 display intellectual disability due to compromised central TH transport and action. As a…”
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